Role of astrocytes in brain function and disease M Sidoryk-Wegrzynowicz, M Wegrzynowicz, E Lee, AB Bowman, ... Toxicologic pathology 39 (1), 115-123, 2011 | 288 | 2011 |
Synaptic failure and α‐synuclein L Calo, M Wegrzynowicz, J Santivañez‐Perez, M Grazia Spillantini Movement Disorders 31 (2), 169-177, 2016 | 180 | 2016 |
Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson’s disease model M Wegrzynowicz, D Bar-On, L Calo’, O Anichtchik, M Iovino, J Xia, ... Acta Neuropathologica 138, 575-595, 2019 | 99 | 2019 |
Alpha-synuclein produces early behavioral alterations via striatal cholinergic synaptic dysfunction by interacting with GluN2D N-methyl-D-aspartate receptor subunit A Tozzi, A de Iure, V Bagetta, M Tantucci, V Durante, A Quiroga-Varela, ... Biological Psychiatry 79 (5), 402-414, 2016 | 99 | 2016 |
Disease‐toxicant screen reveals a neuroprotective interaction between Huntington’s disease and manganese exposure BB Williams, D Li, M Wegrzynowicz, BK Vadodaria, JG Anderson, ... Journal of neurochemistry 112 (1), 227-237, 2010 | 75 | 2010 |
Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system BB Williams, GF Kwakye, M Wegrzynowicz, D Li, M Aschner, KM Erikson, ... Toxicological Sciences 117 (1), 169-179, 2010 | 72 | 2010 |
Mechanisms of ammonia-induced cell death in rat cortical neurons: roles of NMDA receptors and glutathione A Klejman, M Węgrzynowicz, EM Szatmari, B Mioduszewska, M Hetman, ... Neurochemistry international 47 (1-2), 51-57, 2005 | 70 | 2005 |
The L444P Gba1 mutation enhances alpha-synuclein induced loss of nigral dopaminergic neurons in mice A Migdalska-Richards, M Wegrzynowicz, R Rusconi, G Deangeli, ... Brain 140 (10), 2706-2721, 2017 | 62 | 2017 |
Disease-toxicant interactions in manganese exposed Huntington disease mice: early changes in striatal neuron morphology and dopamine metabolism JL Madison, M Wegrzynowicz, M Aschner, AB Bowman PloS one 7 (2), e31024, 2012 | 48 | 2012 |
Diabetes-induced changes in glucose synthesis, intracellular glutathione status and hydroxyl free radical generation in rabbit kidney-cortex tubules K Winiarska, J Drozak, M Wegrzynowicz, T Fraczyk, J Bryla Molecular and cellular biochemistry 261, 91-98, 2004 | 42 | 2004 |
Relationship between gluconeogenesis and glutathione redox state in rabbit kidney-cortex tubules K Winiarska, M Węgrzynowicz, AK Jagielski, J Bryła Metabolism 52 (6), 739-746, 2003 | 42 | 2003 |
Gender and manganese exposure interactions on mouse striatal neuron morphology JL Madison, M Wegrzynowicz, M Aschner, AB Bowman Neurotoxicology 32 (6), 896-906, 2011 | 41 | 2011 |
Differential effects of vanadium, tungsten and molybdenum on inhibition of glucose formation in renal tubules and hepatocytes of control and diabetic rabbits: beneficial action … A Kiersztan, K Winiarska, J Drozak, M Przedlacka, M Wegrzynowicz, ... Molecular and cellular biochemistry 261, 9-21, 2004 | 41 | 2004 |
Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model TJV Bichell, M Wegrzynowicz, KG Tipps, EM Bradley, MA Uhouse, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (6 …, 2017 | 39 | 2017 |
Upregulation of cerebral cortical glutathione synthesis by ammonia in vivo and in cultured glial cells: the role of cystine uptake M Węgrzynowicz, W Hilgier, A Dybel, SS Oja, P Saransaari, J Albrecht Neurochemistry international 50 (7-8), 883-889, 2007 | 32 | 2007 |
Endogenous neuroprotectants in ammonia toxicity in the central nervous system: facts and hypotheses J Albrecht, M Wegrzynowicz Metabolic brain disease 20, 253-263, 2005 | 32 | 2005 |
Direct exposure to ammonia and hyperammonemia increase the extracellular accumulation and degradation of astroglia-derived glutathione in the rat prefrontal cortex W Hilgier, M Węgrzynowicz, J Ruszkiewicz, SS Oja, P Saransaari, ... Toxicological Sciences 117 (1), 163-168, 2010 | 29 | 2010 |
Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised … J Levin, N Sing, S Melbourne, A Morgan, C Mariner, MG Spillantini, ... EBioMedicine 80, 2022 | 28 | 2022 |
Changes in the striatal proteome of YAC128Q mice exhibit gene–environment interactions between mutant huntingtin and manganese M Wegrzynowicz, HK Holt, DB Friedman, AB Bowman Journal of proteome research 11 (2), 1118-1132, 2012 | 27 | 2012 |
L444P Gba1 mutation increases formation and spread of α-synuclein deposits in mice injected with mouse α-synuclein pre-formed fibrils A Migdalska‐Richards, M Wegrzynowicz, IF Harrison, G Verona, V Bellotti, ... PLoS One 15 (8), e0238075, 2020 | 26 | 2020 |