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Khalil Abou-El-Ardat
Khalil Abou-El-Ardat
University Hospital Frankfurt and German Cancer Research Center
Geverifieerd e-mailadres voor dkfz-heidelberg.de
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Association of mutations contributing to clonal hematopoiesis with prognosis in chronic ischemic heart failure
L Dorsheimer, B Assmus, T Rasper, CA Ortmann, A Ecke, ...
JAMA cardiology 4 (1), 25-33, 2019
2202019
Gravity‐sensitive signaling drives 3‐dimensional formation of multicellular thyroid cancer spheroids
J Grosse, M Wehland, J Pietsch, H Schulz, K Saar, N Hübner, C Elles, ...
The FASEB Journal 26 (12), 5124-5140, 2012
972012
Comprehensive molecular characterization of multifocal glioblastoma proves its monoclonal origin and reveals novel insights into clonal evolution and heterogeneity of glioblastomas
K Abou-El-Ardat, M Seifert, K Becker, S Eisenreich, M Lehmann, ...
Neuro-oncology 19 (4), 546-557, 2017
842017
Pooled in vitro and in vivo CRISPR-Cas9 screening identifies tumor suppressors in human colon organoids
BE Michels, MH Mosa, BI Streibl, T Zhan, C Menche, K Abou-El-Ardat, ...
Cell Stem Cell 26 (5), 782-792. e7, 2020
702020
LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU. 1 target genes and induces differentiation in AML
J Barth, K Abou-El-Ardat, D Dalic, N Kurrle, AM Maier, S Mohr, J Schütte, ...
Leukemia 33 (6), 1411-1426, 2019
492019
Epigallocatechin-3-gallate induces apoptosis and cell cycle arrest in HTLV-1-positive and-negative leukemia cells
S Harakeh, K Abu-El-Ardat, M Diab-Assaf, A Niedzwiecki, M El-Sabban, ...
Medical Oncology 25 (1), 30-39, 2008
492008
Ascorbic acid induces apoptosis in adult T-cell leukemia
S Harakeh, M Diab-Assaf, JC Khalife, KA Abu-El-Ardat, E Baydoun, ...
Anticancer research 27 (1A), 289-298, 2007
462007
Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells
S Zielke, N Meyer, M Mari, K Abou-El-Ardat, F Reggiori, SJL van Wijk, ...
Cell death & disease 9 (10), 1-16, 2018
362018
Clonal haematopoiesis in chronic ischaemic heart failure: prognostic role of clone size for DNMT3A- and TET2-driver gene mutations
B Assmus, S Cremer, K Kirschbaum, D Culmann, K Kiefer, L Dorsheimer, ...
European Heart Journal 42 (3), 257-265, 2021
332021
Chronic exposure to simulated space conditions predominantly affects cytoskeleton remodeling and oxidative stress response in mouse fetal fibroblasts
M Beck, M Moreels, R Quintens, K Abou-El-Ardat, H El-Saghire, K Tabury, ...
International Journal of Molecular Medicine 34 (2), 606-615, 2014
322014
Functional dominance of CHIP-mutated hematopoietic stem cells in patients undergoing autologous transplantation
CA Ortmann, L Dorsheimer, K Abou-El-Ardat, J Hoffrichter, B Assmus, ...
Cell reports 27 (7), 2022-2028. e3, 2019
282019
Low dose irradiation of thyroid cells reveals a unique transcriptomic and epigenetic signature in RET/PTC-positive cells
K Abou-El-Ardat, P Monsieurs, N Anastasov, M Atkinson, H Derradji, ...
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 731 (1 …, 2012
282012
Iodine-deficiency-induced long lasting angiogenic reaction in thyroid cancers occurs via a vascular endothelial growth factor–hypoxia inducible factor-1–dependent, but not a …
AC Gérard, K Humblet, C Wilvers, S Poncin, H Derradji, ...
Thyroid 22 (7), 699-708, 2012
262012
Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects
H Derradji, S Bekaert, T De Meyer, P Jacquet, K Abou-El-Ardat, M Ghardi, ...
Developmental Biology 322 (2), 302-313, 2008
242008
Autoregressive higher-order hidden Markov models: exploiting local chromosomal dependencies in the analysis of tumor expression profiles
M Seifert, K Abou-El-Ardat, B Friedrich, B Klink, A Deutsch
PloS one 9 (6), e100295, 2014
232014
Apoptosis induction by Epican Forte in HTLV-1 positive and negative malignant T-cells
S Harakeh, M Diab-Assaf, A Niedzwiecki, J Khalife, K Abu-El-Ardat, ...
Leukemia Research 30 (7), 869-881, 2006
232006
Novel CIC Point Mutations and an Exon-Spanning, Homozygous Deletion Identified in Oligodendroglial Tumors by a Comprehensive Genomic Approach Including …
S Eisenreich, K Abou-El-Ardat, K Szafranski, JA Campos Valenzuela, ...
PloS one 8 (9), e76623, 2013
222013
Epigallocatechin-3-gallate inhibits tax-dependent activation of nuclear factor kappa B and of matrix metalloproteinase 9 in human T-cell lymphotropic virus-1 positive leukemia …
S Harakeh, M Diab-Assaf, R Azar, HMA Hassan, S Tayeb, ...
Asian Pacific Journal of Cancer Prevention 15 (3), 1219-1225, 2014
212014
Multiple somatic mutations for clonal hematopoiesis are associated with increased mortality in patients with chronic heart failure
S Cremer, K Kirschbaum, A Berkowitsch, D John, K Kiefer, L Dorsheimer, ...
Circulation: Genomic and Precision Medicine 13 (4), e003003, 2020
182020
Hematopoietic alterations in chronic heart failure patients by somatic mutations leading to clonal hematopoiesis
L Dorsheimer, B Assmus, T Rasper, CA Ortmann, K Abou-El-Ardat, ...
Haematologica 105 (7), e328, 2020
172020
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