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Parin Shah
Parin Shah
Columbia University, MD Anderson Cancer Center, Harvard University, DFCI
Geverifieerd e-mailadres voor dfci.harvard.edu
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Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ...
Science 352 (6282), 189-196, 2016
38382016
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade
L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ...
Cell 175 (4), 984-997. e24, 2018
10162018
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes
JR Lin, B Izar, S Mei, S Wang, P Shah, PK Sorger
elife, 2018
5152018
Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids
RW Jenkins, AR Aref, PH Lizotte, E Ivanova, S Stinson, CW Zhou, ...
Cancer discovery 8 (2), 196-215, 2018
4352018
A single-cell landscape of high-grade serous ovarian cancer
B Izar, I Tirosh, EH Stover, I Wakiro, MS Cuoco, I Alter, C Rodman, ...
Nature medicine 26 (8), 1271-1279, 2020
3072020
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de‐differentiated state
M Fallahi‐Sichani, V Becker, B Izar, GJ Baker, JR Lin, SA Boswell, P Shah, ...
Molecular systems biology 13 (1), 905, 2017
2392017
Transcriptional mediators of treatment resistance in lethal prostate cancer
MX He, MS Cuoco, J Crowdis, A Bosma-Moody, Z Zhang, K Bi, A Kanodia, ...
Nature medicine 27 (3), 426-433, 2021
1122021
Modification of tumor cell exosome content by transfection with wt-p53 and microRNA-125b expressing plasmid DNA and its effect on macrophage polarization
M Trivedi, M Talekar, P Shah, Q Ouyang, M Amiji
Oncogenesis 5 (8), e250-e250, 2016
772016
Combination wt-p53 and MicroRNA-125b transfection in a genetically engineered lung cancer model using dual CD44/EGFR-targeting nanoparticles
M Talekar, M Trivedi, P Shah, Q Ouyang, A Oka, S Gandham, MM Amiji
Molecular Therapy 24 (4), 759-769, 2016
572016
Bidirectional cross talk between patient‐derived melanoma and cancer‐associated fibroblasts promotes invasion and proliferation
B Izar, CE Joyce, S Goff, NL Cho, PM Shah, G Sharma, J Li, N Ibrahim, ...
Pigment cell & melanoma research 29 (6), 656-668, 2016
402016
Long-chain acyl-CoA synthetase 1 role in sepsis and immunity: perspectives from a parallel review of public transcriptome datasets and of the literature
J Roelands, M Garand, E Hinchcliff, Y Ma, P Shah, M Toufiq, M Alfaki, ...
Frontiers in immunology 10, 2410, 2019
322019
MicroRNA-34a encapsulated in hyaluronic acid nanoparticles induces epigenetic changes with altered mitochondrial bioenergetics and apoptosis in non-small-cell lung cancer cells
M Trivedi, A Singh, M Talekar, G Pawar, P Shah, M Amiji
Scientific Reports 7 (1), 3636, 2017
322017
The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity
P Ho, JC Melms, M Rogava, CJ Frangieh, J Poźniak, SB Shah, Z Walsh, ...
Cancer Cell 41 (7), 1207-1221. e12, 2023
162023
Combined IL-2, agonistic CD3 and 4-1BB stimulation preserve clonotype hierarchy in propagated non-small cell lung cancer tumor-infiltrating lymphocytes
P Shah, MA Forget, ML Frank, P Jiang, D Sakellariou-Thompson, ...
Journal for immunotherapy of cancer 10 (2), 2022
102022
Widespread expression of GDNF throughout rat brain after intranasal delivery of hGDNF plasmid nanoparticles
AEE Aly, BT Harmon, P Shah, O Sesenoglu-Laird, L Padegimas, ...
CELL TRANSPLANTATION 24 (4), 752-753, 2015
3*2015
A cancer cell program promotes T-cell exclusion and resistance to checkpoint blockade.
P Shah, M Cuoco, MJ Su, J Melms, R Leeson, A Kanodia, S Mei, JR Lin, ...
CANCER RESEARCH 80 (19), 43-43, 2020
22020
Single-cell RNA-sequencing and-imaging of melanoma ecosystems reveals sources of resistance to immune checkpoint blockade.
B Izar, L Jerby-Arnon, A Rotem, P Shah, D Liu, G Zhang, B Schilling, ...
Journal of Clinical Oncology 36 (15_suppl), 3074-3074, 2018
22018
Abstract AP19: single–cell rna–sequencing of patient–derived ovarian cancer cells and patient–derived xenograft models
B Izar, E Stover, I Tirosh, A Rotem, P Shah, C Rodman, S Prakadan, ...
Clinical Cancer Research 23 (11_Supplement), AP19-AP19, 2017
22017
Dissecting treatment resistance in patients with ovarian cancer and PDX-models using single-cell RNA-sequencing
B Izar, I Tirosh, E Stover, A Rotem, P Shah, M Cuoco, C Rodman, J Liu, ...
Cancer Research 77 (13_Supplement), 3037-3037, 2017
12017
Abstract CT137: Efficacy and immunological outcomes of non-fucosylated anti-CTLA-4 (BMS-986218)+ degarelix acetate vs. degarelix acetate alone in men with high-risk localized …
PJ McCann, CR Ager, AZ Obradovic, MG Chaimowitz, S Pan, CJ Laplaca, ...
Cancer Research 84 (7_Supplement), CT137-CT137, 2024
2024
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