| Chapter 4: A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-orphanization E van der Horst, J Peironcely, A IJzerman, M Beukers, J Lane, ... Drugs, Structures, Fragments 1, 113, 2012 | 48* | 2012 |
| Combining aggregation with Pareto optimization: a case study in evolutionary molecular design JW Kruisselbrink, MTM Emmerich, T Bäck, A Bender, AP IJzerman, ... International Conference on Evolutionary Multi-Criterion Optimization, 453-467, 2009 | 37 | 2009 |
| Substructure mining of GPCR ligands reveals activity-class specific functional groups in an unbiased manner E van der Horst, Y Okuno, A Bender, AP Ijzerman Journal of chemical information and modeling 49 (2), 348-360, 2009 | 36 | 2009 |
| From peer-reviewed to peer-reproduced in scholarly publishing: the complementary roles of data models and workflows in bioinformatics A González-Beltrán, P Li, J Zhao, MS Avila-Garcia, M Roos, M Thompson, ... PLOS one 10 (7), e0127612, 2015 | 30 | 2015 |
| A prospective cross-screening study on G-protein-coupled receptors: lessons learned in virtual compound library design MPA Sanders, L Roumen, E Van der Horst, JR Lane, HF Vischer, ... Journal of Medicinal Chemistry 55 (11), 5311-5325, 2012 | 30 | 2012 |
| Substructure‐Based Virtual Screening for Adenosine A2A Receptor Ligands E van der Horst, R van der Pijl, T Mulder‐Krieger, A Bender, AP IJzerman ChemMedChem 6 (12), 2302-2311, 2011 | 28 | 2011 |
| Chemogenomics approaches for receptor deorphanization and extensions of the chemogenomics concept to phenotypic space E van der Horst, J E Peironcely, G JP van Westen, O O van den Hoven, ... Current topics in medicinal chemistry 11 (15), 1964-1977, 2011 | 24 | 2011 |
| Multi-objective evolutionary design of adenosine receptor ligands E van der Horst, P Marqués-Gallego, T Mulder-Krieger, J van Veldhoven, ... Journal of chemical information and modeling 52 (7), 1713-1721, 2012 | 23 | 2012 |
| The implicitome: a resource for rationalizing gene-disease associations KM Hettne, M Thompson, HH van Haagen, E Van Der Horst, ... PLoS one 11 (2), e0149621, 2016 | 21 | 2016 |
| Recognition of chemical entities: combining dictionary-based and grammar-based approaches SA Akhondi, KM Hettne, E Van Der Horst, EM Van Mulligen, JA Kors Journal of Cheminformatics 7 (S1), S10, 2015 | 21 | 2015 |
| Chemogenomics: Looking at biology through the lens of chemistry MR Doddareddy, GJP van Westen, E van der Horst, JE Peironcely, ... Statistical Analysis and Data Mining: The ASA Data Science Journal 2 (3 …, 2009 | 20 | 2009 |
| Enhancing search space diversity in multi-objective evolutionary drug molecule design using niching JW Kruisselbrink, A Aleman, MTM Emmerich, AP IJzerman, A Bender, ... Proceedings of the 11th Annual conference on Genetic and evolutionary …, 2009 | 20 | 2009 |
| Nanopublications for exposing experimental data in the life-sciences: a Huntington’s Disease case study E Mina, M Thompson, R Kaliyaperumal, J Zhao, Z Tatum, KM Hettne, ... Journal of biomedical semantics 6 (1), 5, 2015 | 14 | 2015 |
| Evolutionary algorithms for automated drug design towards target molecule properties JW Kruisselbrink, T Bäck, AP IJzerman, E van der Horst Proceedings of the 10th annual conference on Genetic and evolutionary …, 2008 | 12 | 2008 |
| A nanopublishing architecture for biomedical data P Sernadela, E van der Horst, M Thompson, P Lopes, M Roos, JL Oliveira 8th International Conference on Practical Applications of Computational …, 2014 | 10 | 2014 |
| Computational approaches to fragment and substructure discovery and evaluation E van der Horst, AP Ijzerman Fragment-Based Drug Discovery: A Practical Approach, 2008 | 9 | 2008 |
| Linked registries: Connecting rare diseases patient registries through a semantic web layer P Sernadela, L González-Castro, C Carta, E Van Der Horst, P Lopes, ... BioMed research international 2017, 2017 | 7 | 2017 |
| Explain your data by Concept Profile Analysis Web Services K Hettne, R van Schouwen, E Mina, E van der Horst, M Thompson, ... F1000Research 3 (173), 173, 2014 | 6 | 2014 |
| Multidisciplinary Collaboration to Facilitate Hypotheses Generation in Huntington's Disease E Mina, M Thompson, KM Hettne, W van Roon-Mom, R Kaliyaperumal, ... 2015 IEEE 11th International Conference on e-Science, 118-125, 2015 | 4 | 2015 |
| Analyzing molecular landscapes using random walks and information theory M Emmerich, BVY Lee, A Bender, E Faddiev, J Kruisselbrink, AH Deutz, ... Chemistry Central Journal 3 (S1), P20, 2009 | 4 | 2009 |
Andreas BenderReader, University of Cambridge; Team Leader, AstraZenecaVerified email at cam.ac.uk
