| The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization MCL Wu, FH Brennan, JPL Lynch, S Mantovani, S Phipps, RA Wetsel, ... Proceedings of the National Academy of Sciences 110 (23), 9439-9444, 2013 | 166 | 2013 |
| Complement activation in the injured central nervous system: another dual-edged sword? FH Brennan, AJ Anderson, SM Taylor, TM Woodruff, MJ Ruitenberg Journal of neuroinflammation 9, 1-13, 2012 | 146 | 2012 |
| The complement receptor C5aR controls acute inflammation and astrogliosis following spinal cord injury FH Brennan, R Gordon, HW Lao, PJ Biggins, SM Taylor, RJM Franklin, ... Journal of Neuroscience 35 (16), 6517-6531, 2015 | 118 | 2015 |
| Mobilisation of the splenic monocyte reservoir and peripheral CX3CR1 deficiency adversely affects recovery from spinal cord injury LV Blomster, FH Brennan, HW Lao, DW Harle, AR Harvey, MJ Ruitenberg Experimental neurology 247, 226-240, 2013 | 109 | 2013 |
| Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2 FH Brennan, T Jogia, ER Gillespie, LV Blomster, XX Li, B Nowlan, ... JCI insight 4 (9), 2019 | 79 | 2019 |
| Microglia coordinate cellular interactions during spinal cord repair in mice FH Brennan, Y Li, C Wang, A Ma, Q Guo, Y Li, N Pukos, WA Campbell, ... Nature communications 13 (1), 4096, 2022 | 72 | 2022 |
| Therapeutic targeting of complement to modify disease course and improve outcomes in neurological conditions FH Brennan, JD Lee, MJ Ruitenberg, TM Woodruff Seminars in Immunology 28 (3), 292-308, 2016 | 72 | 2016 |
| The spleen as a neuroimmune interface after spinal cord injury BT Noble, FH Brennan, PG Popovich Journal of neuroimmunology 321, 1-11, 2018 | 66 | 2018 |
| Emerging targets for reprograming the immune response to promote repair and recovery of function after spinal cord injury FH Brennan, PG Popovich Current opinion in neurology 31 (3), 334-344, 2018 | 66 | 2018 |
| Longitudinal assessment of white matter pathology in the injured mouse spinal cord through ultra-high field (16.4 T) in vivo diffusion tensor imaging FH Brennan, GJ Cowin, ND Kurniawan, MJ Ruitenberg Neuroimage 82, 574-585, 2013 | 63 | 2013 |
| PI3Kδ inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model PC Low, S Manzanero, N Mohannak, VK Narayana, TH Nguyen, ... Nature communications 5 (1), 1-12, 2014 | 62 | 2014 |
| The alternative receptor for complement component 5a, C5aR2, conveys neuroprotection in traumatic spinal cord injury PJC Biggins, FH Brennan, SM Taylor, TM Woodruff, MJ Ruitenberg Journal of Neurotrauma 34 (12), 2075-2085, 2017 | 40 | 2017 |
| Spinal cord injury causes chronic bone marrow failure RS Carpenter, JM Marbourg, FH Brennan, KA Mifflin, JCE Hall, RR Jiang, ... Nature communications 11 (1), 3702, 2020 | 39 | 2020 |
| IRIS3: integrated cell-type-specific regulon inference server from single-cell RNA-Seq A Ma, C Wang, Y Chang, FH Brennan, A McDermaid, B Liu, C Zhang, ... Nucleic acids research 48 (W1), W275-W286, 2020 | 35 | 2020 |
| Microglia maintain the normal structure and function of the hippocampal astrocyte network Y Du, FH Brennan, PG Popovich, M Zhou Glia 70 (7), 1359-1379, 2022 | 32 | 2022 |
| IVIg attenuates complement and improves spinal cord injury outcomes in mice FH Brennan, ND Kurniawan, J Vukovic, PF Bartlett, F Käsermann, ... Annals of Clinical and Translational Neurology 3 (7), 495-511, 2016 | 31 | 2016 |
| Acute post-injury blockade of α2δ-1 calcium channel subunits prevents pathological autonomic plasticity after spinal cord injury FH Brennan, BT Noble, Y Wang, Z Guan, H Davis, X Mo, C Harris, ... Cell reports 34 (4), 2021 | 29 | 2021 |
| Serial systemic injections of endotoxin (LPS) elicit neuroprotective spinal cord microglia through IL-1-dependent cross talk with endothelial cells CM Freria, FH Brennan, DR Sweet, Z Guan, JC Hall, KA Kigerl, ... Journal of Neuroscience 40 (47), 9103-9120, 2020 | 23 | 2020 |
| Human immune cells infiltrate the spinal cord and impair recovery after spinal cord injury in humanized mice RS Carpenter, RR Jiang, FH Brennan, JCE Hall, MK Gottipati, S Niewiesk, ... Scientific Reports 9 (1), 19105, 2019 | 17 | 2019 |
| Microglia limit lesion expansion and promote functional recovery after spinal cord injury in mice FH Brennan, JCE Hall, Z Guan, PG Popovich bioRxiv, 410258, 2018 | 16 | 2018 |
