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Iris Eke
Iris Eke
Stanford Medicine
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Focal adhesion signaling and therapy resistance in cancer
I Eke, N Cordes
Seminars in cancer biology 31, 65-75, 2015
3212015
β1 Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy
I Eke, Y Deuse, S Hehlgans, K Gurtner, M Krause, M Baumann, ...
The Journal of clinical investigation 122 (4), 1529-1540, 2012
2322012
Three-dimensional cell growth confers radioresistance by chromatin density modification
K Storch, I Eke, K Borgmann, M Krause, C Richter, K Becker, E Schröck, ...
Cancer research 70 (10), 3925-3934, 2010
2132010
Radiobiology goes 3D: how ECM and cell morphology impact on cell survival after irradiation
I Eke, N Cordes
Radiotherapy and Oncology 99 (3), 271-278, 2011
1432011
PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1α
I Eke, U Koch, S Hehlgans, V Sandfort, F Stanchi, D Zips, M Baumann, ...
The Journal of clinical investigation 120 (7), 2516-2527, 2010
1102010
Caveolin-1 mediated radioresistance of 3D grown pancreatic cancer cells
S Hehlgans, I Eke, K Storch, M Haase, GB Baretton, N Cordes
Radiotherapy and Oncology 92 (3), 362-370, 2009
1092009
The future of radiobiology
DG Kirsch, M Diehn, AH Kesarwala, A Maity, MA Morgan, JK Schwarz, ...
JNCI: Journal of the National Cancer Institute 110 (4), 329-340, 2018
962018
Simultaneous β1 integrin-EGFR targeting and radiosensitization of human head and neck cancer
I Eke, K Zscheppang, E Dickreuter, L Hickmann, E Mazzeo, K Unger, ...
Journal of the National Cancer Institute 107 (2), dju419, 2015
912015
EGFR/JIP-4/JNK2 signaling attenuates cetuximab-mediated radiosensitization of squamous cell carcinoma cells
I Eke, L Schneider, C Förster, D Zips, LA Kunz-Schughart, N Cordes
Cancer research 73 (1), 297-306, 2013
892013
3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226
S Hehlgans, I Lange, I Eke, N Cordes
Radiotherapy and oncology 92 (3), 371-378, 2009
892009
Targeting of β1 integrins impairs DNA repair for radiosensitization of head and neck cancer cells
E Dickreuter, I Eke, M Krause, K Borgmann, MA Van Vugt, N Cordes
Oncogene 35 (11), 1353-1362, 2016
792016
Radiation-induced fibrosis: mechanisms and opportunities to mitigate. Report of an NCI workshop, September 19, 2016.
DE Citrin, PGS Prasanna, AJ Walker, ML Freeman, I Eke, ...
Radiation research 188 (1), 1-20, 2017
752017
The small molecule inhibitor QLT0267 Radiosensitizes squamous cell carcinoma cells of the head and neck
I Eke, F Leonhardt, K Storch, S Hehlgans, N Cordes
PLoS One 4 (7), e6434, 2009
702009
Cetuximab attenuates its cytotoxic and radiosensitizing potential by inducing fibronectin biosynthesis
I Eke, K Storch, M Krause, N Cordes
Cancer research 73 (19), 5869-5879, 2013
632013
LIM-only protein FHL2 critically determines survival and radioresistance of pancreatic cancer cells
E Zienert, I Eke, D Aust, N Cordes
Cancer letters 364 (1), 17-24, 2015
582015
Targeting FAK radiosensitizes 3-dimensional grown human HNSCC cells through reduced Akt1 and MEK1/2 signaling
S Hehlgans, I Eke, N Cordes
International Journal of Radiation Oncology* Biology* Physics 83 (5), e669-e676, 2012
572012
Dual targeting of EGFR and focal adhesion kinase in 3D grown HNSCC cell cultures
I Eke, N Cordes
Radiotherapy and Oncology 99 (3), 279-286, 2011
562011
3D matrix-based cell cultures: Automated analysis of tumor cell survival and proliferation
I Eke, S Hehlgans, V Sandfort, N Cordes
International journal of oncology 48 (1), 313-321, 2016
532016
Three-dimensional invasion of human glioblastoma cells remains unchanged by X-ray and carbon ion irradiation in vitro
I Eke, K Storch, I Kästner, A Vehlow, C Faethe, W Mueller-Klieser, ...
International Journal of Radiation Oncology* Biology* Physics 84 (4), e515-e523, 2012
532012
Antiproliferative effects of EGFR tyrosine kinase inhibition and radiation-induced genotoxic injury are attenuated by adhesion to fibronectin
I Eke, V Sandfort, A Mischkus, M Baumann, N Cordes
Radiotherapy and Oncology 80 (2), 178-184, 2006
522006
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Artikelen 1–20