APP mouse models for Alzheimer's disease preclinical studies H Sasaguri, P Nilsson, S Hashimoto, K Nagata, T Saito, B De Strooper, ... The EMBO journal 36 (17), 2473-2487, 2017 | 698 | 2017 |
Altered CpG methylation in sporadic Alzheimer's disease is associated with APP and MAPT dysregulation A Iwata, K Nagata, H Hatsuta, H Takuma, M Bundo, K Iwamoto, ... Human molecular genetics 23 (3), 648-656, 2014 | 147 | 2014 |
Neuronal injury-inducible gene is synergistically regulated by ATF3, c-Jun, and STAT3 through the interaction with Sp1 in damaged neurons S Kiryu-Seo, R Kato, T Ogawa, S Nakagomi, K Nagata, H Kiyama Journal of biological chemistry 283 (11), 6988-6996, 2008 | 92 | 2008 |
Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer’s disease T Mano, K Nagata, T Nonaka, A Tarutani, T Imamura, T Hashimoto, ... Proceedings of the National Academy of Sciences 114 (45), E9645-E9654, 2017 | 86 | 2017 |
Introduction of pathogenic mutations into the mouse Psen1 gene by Base Editor and Target-AID H Sasaguri, K Nagata, M Sekiguchi, R Fujioka, Y Matsuba, S Hashimoto, ... Nature communications 9 (1), 1-8, 2018 | 59 | 2018 |
Generation of App knock-in mice reveals deletion mutations protective against Alzheimer’s disease-like pathology K Nagata, M Takahashi, Y Matsuba, F Okuyama-Uchimura, K Sato, ... Nature communications 9 (1), 1-7, 2018 | 44 | 2018 |
microRNA-124 is down regulated in nerve-injured motor neurons and it potentially targets mRNAs for KLF6 and STAT3 K Nagata, I Hama, S Kiryu-Seo, H Kiyama Neuroscience 256, 426-432, 2014 | 42 | 2014 |
Damage-induced neuronal endopeptidase is critical for presynaptic formation of neuromuscular junctions K Nagata, S Kiryu-Seo, M Maeda, K Yoshida, T Morita, H Kiyama Journal of Neuroscience 30 (20), 6954-6962, 2010 | 38 | 2010 |
Localization and ontogeny of damage-induced neuronal endopeptidase mRNA-expressing neurons in the rat nervous system K Nagata, S Kiryu-Seo, H Kiyama Neuroscience 141 (1), 299-310, 2006 | 22 | 2006 |
ECEL1 mutation implicates impaired axonal arborization of motor nerves in the pathogenesis of distal arthrogryposis K Nagata, S Kiryu-Seo, H Tamada, F Okuyama-Uchimura, H Kiyama, ... Acta neuropathologica 132 (1), 111-126, 2016 | 18 | 2016 |
New Insights of a Neuronal Peptidase DINE/ECEL1: Nerve Development, Nerve Regeneration and Neurogenic Pathogenesis S Kiryu-Seo, K Nagata, TC Saido, H Kiyama Neurochemical research 44 (6), 1279-1288, 2019 | 15 | 2019 |
DNA methylation level of the neprilysin promoter in Alzheimer's disease brains K Nagata, T Mano, S Murayama, TC Saido, A Iwata Neuroscience letters 670, 8-13, 2018 | 13 | 2018 |
Distinct functional consequences of ECEL1/DINE missense mutations in the pathogenesis of congenital contracture disorders K Nagata, M Takahashi, S Kiryu-Seo, H Kiyama, TC Saido Acta neuropathologica communications 5 (1), 83, 2017 | 12 | 2017 |
Methylation changes and aberrant expression of FGFR3 in Lewy body disease neurons T Tsuchida, T Mano, K Koshi-Mano, T Bannai, T Matsubara, S Yamashita, ... Brain research 1697, 59-66, 2018 | 10 | 2018 |
Biology of splicing in Alzheimer's disease research. K Nagata, T Saito, TC Saido, T Morihara Progress in molecular biology and translational science 168, 79-84, 2019 | | 2019 |