Becky Saunders
Becky Saunders
GSK
Geverifieerd e-mailadres voor crick.ac.uk
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Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress
ZT Schug, B Peck, DT Jones, Q Zhang, S Grosskurth, IS Alam, ...
Cancer cell 27 (1), 57-71, 2015
4872015
Deletion of Lys224 in regulatory domain 4 of Factor H reveals a novel pathomechanism for dense deposit disease (MPGN II)
C Licht, S Heinen, M Józsi, I Löschmann, RE Saunders, SJ Perkins, ...
Kidney international 70 (1), 42-50, 2006
2282006
The interactive Factor H–atypical hemolytic uremic syndrome mutation database and website: update and integration of membrane cofactor protein and Factor I mutations with …
RE Saunders, C Abarrategui‐Garrido, V Frémeaux‐Bacchi, ...
Human mutation 28 (3), 222-234, 2007
1802007
Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies
M Steckel, M Molina-Arcas, B Weigelt, M Marani, PH Warne, H Kuznetsov, ...
Cell research 22 (8), 1227-1245, 2012
1742012
Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer
EC de Bruin, C Cowell, PH Warne, M Jiang, RE Saunders, MA Melnick, ...
Cancer discovery 4 (5), 606-619, 2014
1652014
Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments
B Peck, ZT Schug, Q Zhang, B Dankworth, DT Jones, E Smethurst, ...
Cancer & metabolism 4 (1), 1-18, 2016
1602016
Factor H and atypical hemolytic uremic syndrome: mutations in the C-terminus cause structural changes and defective recognition functions
M Józsi, S Heinen, A Hartmann, CW Ostrowicz, S Hälbich, H Richter, ...
Journal of the American Society of Nephrology 17 (1), 170-177, 2006
1502006
Genome‐wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target
M Gerlinger, CR Santos, B Spencer‐Dene, P Martinez, D Endesfelder, ...
The Journal of pathology 227 (2), 146-156, 2012
1142012
Multiomic analysis of the UV-induced DNA damage response
S Boeing, L Williamson, V Encheva, I Gori, RE Saunders, R Instrell, ...
Cell reports 15 (7), 1597-1610, 2016
1072016
The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma
H Miess, B Dankworth, AM Gouw, M Rosenfeldt, W Schmitz, M Jiang, ...
Oncogene 37 (40), 5435-5450, 2018
1052018
An interactive web database of factor H‐associated hemolytic uremic syndrome mutations: insights into the structural consequences of disease‐associated mutations
RE Saunders, THJ Goodship, PF Zipfel, SJ Perkins
Human mutation 27 (1), 21-30, 2006
103*2006
Genome‐wide siRNA screen reveals amino acid starvation‐induced autophagy requires SCOC and WAC
NC McKnight, HBJ Jefferies, EA Alemu, RE Saunders, M Howell, ...
The EMBO journal 31 (8), 1931-1946, 2012
1022012
Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila
MC Wehr, MV Holder, I Gailite, RE Saunders, TM Maile, E Ciirdaeva, ...
Nature cell biology 15 (1), 61-71, 2013
1002013
Factor XI deficiency database: an interactive web database of mutations, phenotypes, and structural analysis tools
RE Saunders, NM O'Connell, CA Lee, DJ Perry, SJ Perkins
Human mutation 26 (3), 192-198, 2005
682005
Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival
F Baenke, S Dubuis, C Brault, B Weigelt, B Dankworth, B Griffiths, M Jiang, ...
The Journal of pathology 237 (2), 152-165, 2015
642015
Charge environments around phosphorylation sites in proteins
J Kitchen, RE Saunders, J Warwicker
BMC structural biology 8 (1), 1-11, 2008
372008
Association of a factor H mutation with hemolytic uremic syndrome following a diarrheal illness
MM Edey, PA Mead, RE Saunders, L Strain, SJ Perkins, THJ Goodship, ...
American journal of kidney diseases 51 (3), 487-490, 2008
312008
Structural analysis of eight novel and 112 previously reported missense mutations in the interactive FXI mutation database reveals new insight on FXI deficiency
RE Saunders, N Shiltagh, K Gomez, G Mellars, C Cooper, DJ Perry, ...
Thrombosis and haemostasis 102 (08), 287-301, 2009
292009
A CRISPR platform for targeted in vivo screens identifies Toxoplasma gondii virulence factors in mice
J Young, C Dominicus, J Wagener, S Butterworth, X Ye, G Kelly, M Ordan, ...
Nature communications 10 (1), 1-11, 2019
222019
CoagMDB: a database analysis of missense mutations within four conserved domains in five vitamin K–dependent coagulation serine proteases using a text‐mining tool
RE Saunders, SJ Perkins
Human mutation 29 (3), 333-344, 2008
212008
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Artikelen 1–20