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Sophie Brachat
Sophie Brachat
Data Science Investigator, Musculoskeletal disease, Novartis Institutes for Biomedical Research
Geverifieerd e-mailadres voor novartis.com
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Functional profiling of the Saccharomyces cerevisiae genome
G Giaever, AM Chu, L Ni, C Connelly, L Riles, S Véronneau, S Dow, ...
nature 418 (6896), 387-391, 2002
50462002
The Ashbya gossypii Genome as a Tool for Mapping the Ancient Saccharomyces cerevisiae Genome
FS Dietrich, S Voegeli, S Brachat, A Lerch, K Gates, S Steiner, C Mohr, ...
Science 304 (5668), 304-307, 2004
7482004
GDF11 increases with age and inhibits skeletal muscle regeneration
MA Egerman, SM Cadena, JA Gilbert, A Meyer, HN Nelson, SE Swalley, ...
Cell metabolism 22 (1), 164-174, 2015
5732015
An antibody blocking activin type II receptors induces strong skeletal muscle hypertrophy and protects from atrophy
E Lach-Trifilieff, GC Minetti, KA Sheppard, C Ibebunjo, JN Feige, ...
Molecular and cellular biology, 2014
3212014
Genomic and proteomic profiling reveals reduced mitochondrial function and disruption of the neuromuscular junction driving rat sarcopenia
C Ibebunjo, JM Chick, T Kendall, JK Eash, C Li, Y Zhang, C Vickers, Z Wu, ...
Molecular and cellular biology 33 (2), 194-212, 2013
3022013
Contribution of Horizontal Gene Transfer to the Evolution of Saccharomyces cerevisiae
C Hall, S Brachat, FS Dietrich
Eukaryotic cell 4 (6), 1102-1115, 2005
2942005
A long non-coding RNA, LncMyoD, regulates skeletal muscle differentiation by blocking IMP2-mediated mRNA translation
C Gong, Z Li, K Ramanujan, I Clay, Y Zhang, S Lemire-Brachat, DJ Glass
Developmental cell 34 (2), 181-191, 2015
2602015
High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions
D Hoepfner, SB Helliwell, H Sadlish, S Schuierer, I Filipuzzi, S Brachat, ...
Microbiological research 169 (2-3), 107-120, 2014
1632014
Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii
S Brachat, FS Dietrich, S Voegeli, Z Zhang, L Stuart, A Lerch, K Gates, ...
Genome biology 4, 1-13, 2003
1402003
Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolism
B Fournier, B Murray, S Gutzwiller, S Marcaletti, D Marcellin, S Bergling, ...
Molecular and cellular biology 32 (14), 2871-2879, 2012
1182012
Expansion of human mesenchymal stromal cells from fresh bone marrow in a 3D scaffold-based system under direct perfusion
A Papadimitropoulos, E Piccinini, S Brachat, A Braccini, D Wendt, ...
PloS one 9 (7), e102359, 2014
1172014
Genomic profiling reveals that transient adipogenic activation is a hallmark of mouse models of skeletal muscle regeneration
L Lukjanenko, S Brachat, E Pierrel, E Lach-Trifilieff, JN Feige
PloS one 8 (8), e71084, 2013
792013
Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space
SM Cadena, Y Zhang, J Fang, S Brachat, P Kuss, E Giorgetti, LS Stodieck, ...
Scientific reports 9 (1), 9397, 2019
472019
Modulation of microglia by voluntary exercise or CSF1R inhibition prevents age-related loss of functional motor units
E Giorgetti, M Panesar, Y Zhang, S Joller, M Ronco, M Obrecht, ...
Cell reports 29 (6), 1539-1554. e7, 2019
462019
Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy
A Sen, DN Dimlich, KG Guruharsha, MW Kankel, K Hori, T Yokokura, ...
Proceedings of the National Academy of Sciences 110 (26), E2371-E2380, 2013
442013
Continuous digital monitoring of walking speed in frail elderly patients: noninterventional validation study and longitudinal clinical trial
A Mueller, HA Hoefling, A Muaremi, J Praestgaard, LC Walsh, O Bunte, ...
JMIR mHealth and uHealth 7 (11), e15191, 2019
432019
The Ashbya Genome Database (AGD)—a tool for the yeast community and genome biologists
L Hermida, S Brachat, S Voegeli, P Philippsen, M Primig
Nucleic acids research 33 (suppl_1), D348-D352, 2005
282005
GermOnline, a cross‐species community knowledgebase on germ cell differentiation
C Wiederkehr, R Basavaraj, C Sarrauste de Menthiere, L Hermida, ...
Nucleic acids research 32 (suppl_1), D560-D567, 2004
252004
Angiopoietin-like 3-derivative LNA043 for cartilage regeneration in osteoarthritis: a randomized phase 1 trial
N Gerwin, C Scotti, C Halleux, M Fornaro, J Elliott, Y Zhang, K Johnson, ...
Nature Medicine 28 (12), 2633-2645, 2022
222022
Ten simple rules to power drug discovery with data science
E Ferrero, S Brachat, JL Jenkins, P Marc, P Skewes-Cox, RC Altshuler, ...
PLoS computational biology 16 (8), e1008126, 2020
222020
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Artikelen 1–20