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Zheng Sun
Zheng Sun
Baylor College of Medicine
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Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2
XJ Wang, Z Sun, NF Villeneuve, S Zhang, F Zhao, Y Li, W Chen, X Yi, ...
Carcinogenesis 29 (6), 1235-1243, 2008
9302008
A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62
A Lau, XJ Wang, F Zhao, NF Villeneuve, T Wu, T Jiang, Z Sun, E White, ...
Molecular and cellular biology 30 (13), 3275-3285, 2010
8532010
Dual roles of Nrf2 in cancer
A Lau, NF Villeneuve, Z Sun, PK Wong, DD Zhang
Pharmacological research 58 (5-6), 262-270, 2008
7822008
A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism
D Feng, T Liu, Z Sun, A Bugge, SE Mullican, T Alenghat, XS Liu, MA Lazar
Science's STKE 331 (6022), 1315, 2011
7242011
Direct interaction between Nrf2 and p21Cip1/WAF1 upregulates the Nrf2-mediated antioxidant response
W Chen, Z Sun, XJ Wang, T Jiang, Z Huang, D Fang, DD Zhang
Molecular cell 34 (6), 663-673, 2009
6942009
Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response
Z Sun, YE Chin, DD Zhang
Molecular and cellular biology 29 (10), 2658-2672, 2009
4232009
Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response
Z Sun, Z Huang, DD Zhang
PloS one 4 (8), e6588, 2009
3842009
Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2
Z Sun, S Zhang, JY Chan, DD Zhang
Molecular and cellular biology 27 (18), 6334-6349, 2007
3742007
Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway
DD Zhang, SC Lo, Z Sun, GM Habib, MW Lieberman, M Hannink
Journal of Biological Chemistry 280 (34), 30091-30099, 2005
3472005
Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration
Z Sun, RA Miller, RT Patel, J Chen, R Dhir, H Wang, D Zhang, MJ Graham, ...
Nature Medicine 18 (6), 934-942, 2012
3322012
Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock
Y Zhang, B Fang, MJ Emmett, M Damle, Z Sun, D Feng, SM Armour, ...
Science 348 (6242), 1488-1492, 2015
3022015
Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor
Z Sun, D Feng, B Fang, SE Mullican, SH You, HW Lim, LJ Everett, ...
Molecular cell 52 (6), 769-782, 2013
2442013
Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo
B Fang, LJ Everett, J Jager, E Briggs, SM Armour, D Feng, A Roy, ...
Cell 159 (5), 1140-1152, 2014
2182014
Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo
SH You, HW Lim, Z Sun, M Broache, KJ Won, MA Lazar
Nature structural & molecular biology 20 (2), 182-187, 2013
2142013
Genome-nuclear lamina interactions regulate cardiac stem cell lineage restriction
A Poleshko, PP Shah, M Gupta, A Babu, MP Morley, LJ Manderfield, ...
Cell 171 (3), 573-587. e14, 2017
1852017
Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer
NA Zhao, J Cao, L Xu, Q Tang, LE Dobrolecki, X Lv, M Talukdar, Y Lu, ...
The Journal of clinical investigation 128 (4), 1283-1299, 2018
1762018
Dissociating fatty liver and diabetes
Z Sun, MA Lazar
Trends in endocrinology & metabolism 24 (1), 4-12, 2013
1692013
Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1–Cul3 interaction
XJ Wang, Z Sun, W Chen, Y Li, NF Villeneuve, DD Zhang
Toxicology and applied pharmacology 230 (3), 383-389, 2008
1572008
KPNA6 (Importin α7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response
Z Sun, T Wu, F Zhao, A Lau, CM Birch, DD Zhang
Molecular and cellular biology 31 (9), 1800-1811, 2011
1252011
USP15 negatively regulates Nrf2 through deubiquitination of Keap1
NF Villeneuve, W Tian, T Wu, Z Sun, A Lau, E Chapman, D Fang, ...
Molecular cell 51 (1), 68-79, 2013
1142013
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