Jens Luebeck
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Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions
JP Shen, D Zhao, R Sasik, J Luebeck, A Birmingham, ...
Nature methods 14 (6), 573-576, 2017
2132017
Quantitative missense variant effect prediction using large-scale mutagenesis data
VE Gray, RJ Hause, J Luebeck, J Shendure, DM Fowler
Cell systems 6 (1), 116-124. e3, 2018
672018
Circular ecDNA promotes accessible chromatin and high oncogene expression
S Wu, KM Turner, N Nguyen, R Raviram, M Erb, J Santini, J Luebeck, ...
Nature 575 (7784), 699-703, 2019
612019
Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis
D Zhao, MG Badur, J Luebeck, JH Magaņa, A Birmingham, R Sasik, ...
Molecular cell 69 (4), 699-708. e7, 2018
402018
Exploring the landscape of focal amplifications in cancer using AmpliconArchitect
V Deshpande, J Luebeck, NPD Nguyen, M Bakhtiari, KM Turner, ...
Nature communications 10 (1), 1-14, 2019
282019
Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers
H Kim, NP Nguyen, K Turner, S Wu, AD Gujar, J Luebeck, J Liu, ...
Nature Genetics 52 (9), 891-897, 2020
13*2020
ViFi: accurate detection of viral integration and mRNA fusion reveals indiscriminate and unregulated transcription in proximal genomic regions in cervical cancer
ND Nguyen, V Deshpande, J Luebeck, PS Mischel, V Bafna
Nucleic acids research 46 (7), 3309-3325, 2018
132018
EcSeg: Semantic Segmentation of Metaphase Images Containing Extrachromosomal DNA
U Rajkumar, K Turner, J Luebeck, V Deshpande, M Chandraker, ...
iScience 21, 428-435, 2019
42019
AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications
J Luebeck, C Coruh, SR Dehkordi, JT Lange, KM Turner, V Deshpande, ...
Nature Communications 11 (1), 1-14, 2020
2*2020
CRISPR/Cas9 gene editing of hematopoietic stem cells from patients with Friedreich’s ataxia
CJ Rocca, JN Rainaldi, J Sharma, Y Shi, JH Haquang, J Luebeck, P Mali, ...
Molecular Therapy-Methods & Clinical Development, 2020
2020
Alignment Methods for Optical Maps
JC Luebeck
UC San Diego, 2019
2019
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Artikelen 1–11