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Paul Johnson
Paul Johnson
Professor of Paediatric Surgery, University of Oxford; Director of Oxford Islet Transplant Programme
Geverifieerd e-mailadres voor nds.ox.ac.uk
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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ...
Nature genetics 42 (2), 105-116, 2010
24962010
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
BF Voight, LJ Scott, V Steinthorsdottir, AP Morris, C Dina, RP Welch, ...
Nature genetics 42 (7), 579-589, 2010
21612010
Parental origin of sequence variants associated with complex diseases
A Kong, V Steinthorsdottir, G Masson, G Thorleifsson, P Sulem, ...
Nature 462 (7275), 868-874, 2009
6562009
Voltage-gated ion channels in human pancreatic β-cells: electrophysiological characterization and role in insulin secretion
M Braun, R Ramracheya, M Bengtsson, Q Zhang, J Karanauskaite, ...
Diabetes 57 (6), 1618-1628, 2008
5052008
Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes
I Morán, I Akerman, M Van De Bunt, R Xie, M Benazra, T Nammo, L Arnes, ...
Cell metabolism 16 (4), 435-448, 2012
4812012
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes
RJ Strawbridge, J Dupuis, I Prokopenko, A Barker, E Ahlqvist, D Rybin, ...
Diabetes 60 (10), 2624-2634, 2011
4512011
Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes–associated variants
TJ Nicolson, EA Bellomo, N Wijesekara, MK Loder, JM Baldwin, ...
Diabetes 58 (9), 2070-2083, 2009
4442009
The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in …
NL Beer, ND Tribble, LJ McCulloch, C Roos, PRV Johnson, ...
Human molecular genetics 18 (21), 4081-4088, 2009
4302009
A KATP Channel-Dependent Pathway within α Cells Regulates Glucagon Release from Both Rodent and Human Islets of Langerhans
PE MacDonald, YZD Marinis, R Ramracheya, A Salehi, X Ma, ...
PLoS biology 5 (6), e143, 2007
3132007
Spatiotemporal analysis of human intestinal development at single-cell resolution
D Fawkner-Corbett, A Antanaviciute, K Parikh, M Jagielowicz, AS Gerós, ...
Cell 184 (3), 810-826. e23, 2021
2942021
Familial persistent hyperinsulinemic hypoglycemia of infancy and mutations in the sulfonylurea receptor
MJ Dunne, C Kane, RM Shepherd, JA Sanchez, RFL James, ...
New England Journal of Medicine 336 (10), 703-706, 1997
2941997
Loss of functional KATP channels in pancreatic β–cells causes persistent hyperinsulinemic hypoglycemia of infancy
C Kane, RM Shepherd, PE Squires, PRV Johnson, RFL James, PJ Milla, ...
Nature medicine 2 (12), 1344-1347, 1996
2831996
Observations on radioactivity from the Chernobyl accident
RS Cambray, PA Cawse, JA Garland, JAB Gibson, P Johnson, GNJ Lewis, ...
Nucl. Energy 26 (2), 77-101, 1987
2761987
Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes
AH Rosengren, M Braun, T Mahdi, SA Andersson, ME Travers, M Shigeto, ...
Diabetes 61 (7), 1726-1733, 2012
2682012
γ-Aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic β-cells
M Braun, R Ramracheya, M Bengtsson, A Clark, JN Walker, PR Johnson, ...
Diabetes 59 (7), 1694-1701, 2010
2612010
Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes
Q Zhang, R Ramracheya, C Lahmann, A Tarasov, M Bengtsson, O Braha, ...
Cell metabolism 18 (6), 871-882, 2013
2522013
The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation
M Cnop, SJ Hughes, M Igoillo-Esteve, MB Hoppa, F Sayyed, ...
Diabetologia 53, 321-330, 2010
2502010
Lipotoxicity disrupts incretin-regulated human β cell connectivity
DJ Hodson, RK Mitchell, EA Bellomo, G Sun, L Vinet, P Meda, D Li, WH Li, ...
The Journal of clinical investigation 123 (10), 4182-4194, 2013
2322013
The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis
M van de Bunt, KJ Gaulton, L Parts, I Moran, PR Johnson, CM Lindgren, ...
PloS one 8 (1), e55272, 2013
2312013
Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?
JN Walker, R Ramracheya, Q Zhang, PRV Johnson, M Braun, P Rorsman
Diabetes, Obesity and Metabolism 13, 95-105, 2011
2102011
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Artikelen 1–20