Allostery: absence of a change in shape does not imply that allostery is not at play CJ Tsai, A Del Sol, R Nussinov Journal of molecular biology 378 (1), 1-11, 2008 | 501 | 2008 |
Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): a prospective, multicentre, cohort study T van der Hulle, WY Cheung, S Kooij, LFM Beenen, T van Bemmel, ... The Lancet 390 (10091), 289-297, 2017 | 497 | 2017 |
The origin of allosteric functional modulation: multiple pre-existing pathways A Del Sol, CJ Tsai, B Ma, R Nussinov Structure 17 (8), 1042-1050, 2009 | 416 | 2009 |
Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms CJ Tsai, A Del Sol, R Nussinov Molecular Biosystems 5 (3), 207-216, 2009 | 401 | 2009 |
Stemness of the hybrid epithelial/mesenchymal state in breast cancer and its association with poor survival A Grosse-Wilde, A Fouquier d’Hérouël, E McIntosh, G Ertaylan, A Skupin, ... PloS one 10 (5), e0126522, 2015 | 367 | 2015 |
Residues crucial for maintaining short paths in network communication mediate signaling in proteins A del Sol, H Fujihashi, D Amoros, R Nussinov Molecular systems biology 2 (1), 2006.0019, 2006 | 367 | 2006 |
Quiescence modulates stem cell maintenance and regenerative capacity in the aging brain G Kalamakis, D Brüne, S Ravichandran, J Bolz, W Fan, F Ziebell, T Stiehl, ... Cell 176 (6), 1407-1419. e14, 2019 | 312 | 2019 |
Integrating pathways of Parkinson's disease in a molecular interaction map KA Fujita, M Ostaszewski, Y Matsuoka, S Ghosh, E Glaab, C Trefois, ... Molecular neurobiology 49, 88-102, 2014 | 267 | 2014 |
Automatic methods for predicting functionally important residues A del Sol Mesa, F Pazos, A Valencia Journal of molecular biology 326 (4), 1289-1302, 2003 | 249 | 2003 |
Assessment of network module identification across complex diseases S Choobdar, ME Ahsen, J Crawford, M Tomasoni, T Fang, D Lamparter, ... Nature methods 16 (9), 843-852, 2019 | 243 | 2019 |
Diseases as network perturbations A Del Sol, R Balling, L Hood, D Galas Current opinion in biotechnology 21 (4), 566-571, 2010 | 239 | 2010 |
Identification of amino acid residues crucial for chemokine receptor dimerization P Hernanz-Falcon, JM Rodríguez-Frade, A Serrano, D Juan, A Del Sol, ... Nature immunology 5 (2), 216-223, 2004 | 232 | 2004 |
Small‐world network approach to identify key residues in protein–protein interaction A Del Sol, P O'Meara Proteins: Structure, Function, and Bioinformatics 58 (3), 672-682, 2005 | 216 | 2005 |
Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects TY de Soysa, SS Ranade, S Okawa, S Ravichandran, Y Huang, ... Nature 572 (7767), 120-124, 2019 | 215 | 2019 |
A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition M Moes, A Le Béchec, I Crespo, C Laurini, A Halavatyi, G Vetter, ... PloS one 7 (4), e35440, 2012 | 204 | 2012 |
Residue centrality, functionally important residues, and active site shape: analysis of enzyme and non‐enzyme families A del Sol, H Fujihashi, D Amoros, R Nussinov Protein Science 15 (9), 2120-2128, 2006 | 187 | 2006 |
Topology of small-world networks of protein–protein complex structures A Del Sol, H Fujihashi, P O'Meara Bioinformatics 21 (8), 1311-1315, 2005 | 166 | 2005 |
Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells CW Van Den Berg, S Okawa, SM Chuva de Sousa Lopes, L Van Iperen, ... Development 142 (18), 3231-3238, 2015 | 156 | 2015 |
Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs. Nature Communications, 2014 | 133 | 2014 |
Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration MCP Moiseeva V, Cisneros A, Sica V, Deryagin O, Lai Y, Jung S, Andrés E, An ... Nature 613 (7942), 169-178, 2023 | 114 | 2023 |