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Sebastiaan Engelborghs
Sebastiaan Engelborghs
Full Professor Vrije Universiteit Brussel & University of Antwerp
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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ...
Nature genetics 41 (10), 1088-1093, 2009
4296*2009
Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria
B Dubois, HH Feldman, C Jacova, H Hampel, JL Molinuevo, K Blennow, ...
The Lancet Neurology 13 (6), 614-629, 2014
37812014
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
24822019
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ...
Nature genetics 43 (5), 429-435, 2011
22552011
Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21
M Cruts, I Gijselinck, J Van Der Zee, S Engelborghs, H Wils, D Pirici, ...
Nature 442 (7105), 920-924, 2006
17342006
Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis
WJ Jansen, R Ossenkoppele, DL Knol, BM Tijms, P Scheltens, ...
Jama 313 (19), 1924-1938, 2015
16312015
New insights into the genetic etiology of Alzheimer’s disease and related dementias
C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ...
Nature genetics 54 (4), 412-436, 2022
13592022
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373-1384, 2017
9622017
APOE and Alzheimer disease: a major gene with semi-dominant inheritance
E Genin, D Hannequin, D Wallon, K Sleegers, M Hiltunen, O Combarros, ...
Molecular psychiatry 16 (9), 903-907, 2011
8082011
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
G Kleinberger, Y Yamanishi, M Suárez-Calvet, E Czirr, E Lohmann, ...
Science translational medicine 6 (243), 243ra86-243ra86, 2014
7972014
A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene …
I Gijselinck, T Van Langenhove, J van der Zee, K Sleegers, S Philtjens, ...
The Lancet Neurology 11 (1), 54-65, 2012
7912012
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy
GU Höglinger, NM Melhem, DW Dickson, PMA Sleiman, LS Wang, L Klei, ...
Nature genetics 43 (7), 699-705, 2011
6512011
Diagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly people
G De Meyer, F Shapiro, H Vanderstichele, E Vanmechelen, ...
Archives of neurology 67 (8), 949-956, 2010
5352010
A practical guide to immunoassay method validation
U Andreasson, A Perret-Liaudet, LJC van Waalwijk van Doorn, ...
Frontiers in neurology 6, 179, 2015
5222015
A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies
MA Nalls, R Duran, G Lopez, M Kurzawa-Akanbi, IG McKeith, ...
JAMA neurology 70 (6), 727-735, 2013
5042013
sTREM 2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers
M Suárez‐Calvet, G Kleinberger, MÁ Araque Caballero, M Brendel, ...
EMBO molecular medicine 8 (5), 466-476, 2016
4962016
The lateralized linguistic cerebellum: a review and a new hypothesis
P Marien, S Engelborghs, F Fabbro, PP De Deyn
Brain and language 79 (3), 580-600, 2001
4462001
Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology
J Chapuis, F Hansmannel, M Gistelinck, A Mounier, ...
Molecular psychiatry 18 (11), 1225-1234, 2013
4312013
CSF biomarker variability in the Alzheimer's Association quality control program
N Mattsson, U Andreasson, S Persson, MC Carrillo, S Collins, S Chalbot, ...
Alzheimer's & Dementia 9 (3), 251-261, 2013
4062013
Prevalence and prognosis of Alzheimer’s disease at the mild cognitive impairment stage
SJB Vos, F Verhey, L Frölich, J Kornhuber, J Wiltfang, W Maier, O Peters, ...
Brain 138 (5), 1327-1338, 2015
4032015
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Artikelen 1–20