Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ... Nature genetics 41 (10), 1088-1093, 2009 | 4240* | 2009 |
Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria B Dubois, HH Feldman, C Jacova, H Hampel, JL Molinuevo, K Blennow, ... The Lancet Neurology 13 (6), 614-629, 2014 | 3734 | 2014 |
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2402 | 2019 |
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ... Nature genetics 43 (5), 429-435, 2011 | 2232 | 2011 |
Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21 M Cruts, I Gijselinck, J Van Der Zee, S Engelborghs, H Wils, D Pirici, ... Nature 442 (7105), 920-924, 2006 | 1719 | 2006 |
Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis WJ Jansen, R Ossenkoppele, DL Knol, BM Tijms, P Scheltens, ... Jama 313 (19), 1924-1938, 2015 | 1587 | 2015 |
New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 1218 | 2022 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 950 | 2017 |
APOE and Alzheimer disease: a major gene with semi-dominant inheritance E Genin, D Hannequin, D Wallon, K Sleegers, M Hiltunen, O Combarros, ... Molecular psychiatry 16 (9), 903-907, 2011 | 802 | 2011 |
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis G Kleinberger, Y Yamanishi, M Suárez-Calvet, E Czirr, E Lohmann, ... Science translational medicine 6 (243), 243ra86-243ra86, 2014 | 787 | 2014 |
A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene … I Gijselinck, T Van Langenhove, J van der Zee, K Sleegers, S Philtjens, ... The Lancet Neurology 11 (1), 54-65, 2012 | 785 | 2012 |
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy GU Höglinger, NM Melhem, DW Dickson, PMA Sleiman, LS Wang, L Klei, ... Nature genetics 43 (7), 699-705, 2011 | 645 | 2011 |
Diagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly people G De Meyer, F Shapiro, H Vanderstichele, E Vanmechelen, ... Archives of neurology 67 (8), 949-956, 2010 | 536 | 2010 |
A practical guide to immunoassay method validation U Andreasson, A Perret-Liaudet, LJC van Waalwijk van Doorn, ... Frontiers in neurology 6, 179, 2015 | 509 | 2015 |
A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies MA Nalls, R Duran, G Lopez, M Kurzawa-Akanbi, IG McKeith, ... JAMA neurology 70 (6), 727-735, 2013 | 496 | 2013 |
sTREM 2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers M Suárez‐Calvet, G Kleinberger, MÁ Araque Caballero, M Brendel, ... EMBO molecular medicine 8 (5), 466-476, 2016 | 482 | 2016 |
The lateralized linguistic cerebellum: a review and a new hypothesis P Marien, S Engelborghs, F Fabbro, PP De Deyn Brain and language 79 (3), 580-600, 2001 | 444 | 2001 |
Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology J Chapuis, F Hansmannel, M Gistelinck, A Mounier, ... Molecular psychiatry 18 (11), 1225-1234, 2013 | 425 | 2013 |
CSF biomarker variability in the Alzheimer's Association quality control program N Mattsson, U Andreasson, S Persson, MC Carrillo, S Collins, S Chalbot, ... Alzheimer's & Dementia 9 (3), 251-261, 2013 | 399 | 2013 |
Prevalence and prognosis of Alzheimer’s disease at the mild cognitive impairment stage SJB Vos, F Verhey, L Frölich, J Kornhuber, J Wiltfang, W Maier, O Peters, ... Brain 138 (5), 1327-1338, 2015 | 394 | 2015 |