| Lenvatinib plus anti-PD-1 antibody combination treatment activates CD8+ T cells through reduction of tumor-associated macrophage and activation of the interferon … YU Kato, K Tabata, T Kimura, A Yachie-Kinoshita, Y Ozawa, K Yamada, ... PloS one 14 (2), e0212513, 2019 | 347 | 2019 |
| Paradoxical ATP elevation in ischemic penumbra revealed by quantitative imaging mass spectrometry K Hattori, M Kajimura, T Hishiki, T Nakanishi, A Kubo, Y Nagahata, ... Antioxidants & redox signaling 13 (8), 1157-1167, 2010 | 121 | 2010 |
| Roles of hemoglobin Allostery in hypoxia-induced metabolic alterations in erythrocytes: simulation and its verification by metabolome analysis A Kinoshita, K Tsukada, T Soga, T Hishiki, Y Ueno, Y Nakayama, ... Journal of Biological Chemistry 282 (14), 10731-10741, 2007 | 117 | 2007 |
| Simulation study of methemoglobin reduction in erythrocytes: differential contributions of two pathways to tolerance to oxidative stress A Kinoshita, Y Nakayama, T Kitayama, M Tomita The FEBS journal 274 (6), 1449-1458, 2007 | 93 | 2007 |
| CD24 tracks divergent pluripotent states in mouse and human cells N Shakiba, CA White, YY Lipsitz, A Yachie-Kinoshita, PD Tonge, ... Nature communications 6 (1), 7329, 2015 | 91 | 2015 |
| Dynamic simulation of red blood cell metabolism and its application to the analysis of a pathological condition Y Nakayama, A Kinoshita, M Tomita Theoretical Biology and Medical Modelling 2, 1-11, 2005 | 76 | 2005 |
| In silico modeling and metabolome analysis of long-stored erythrocytes to improve blood storage methods T Nishino, A Yachie-Kinoshita, A Hirayama, T Soga, M Suematsu, ... Journal of biotechnology 144 (3), 212-223, 2009 | 62 | 2009 |
| Modeling signaling‐dependent pluripotency with Boolean logic to predict cell fate transitions A Yachie‐Kinoshita, K Onishi, J Ostblom, MA Langley, E Posfai, J Rossant, ... Molecular systems biology 14 (1), e7952, 2018 | 58 | 2018 |
| Hybrid dynamic/static method for large-scale simulation of metabolism K Yugi, Y Nakayama, A Kinoshita, M Tomita Theoretical Biology and Medical Modelling 2, 1-11, 2005 | 45 | 2005 |
| Dynamic simulation and metabolome analysis of long-term erythrocyte storage in adenine–guanosine solution T Nishino, A Yachie-Kinoshita, A Hirayama, T Soga, M Suematsu, ... PLoS One 8 (8), e71060, 2013 | 42 | 2013 |
| Hypotaurine is an energy-saving hepatoprotective compound against ischemia-reperfusion injury of the rat liver T Sakuragawa, T Hishiki, Y Ueno, S Ikeda, T Soga, A Yachie-Kinoshita, ... Journal of clinical biochemistry and nutrition 46 (2), 126-134, 2010 | 40 | 2010 |
| A metabolic model of human erythrocytes: practical application of the E-Cell Simulation Environment A Yachie-Kinoshita, T Nishino, H Shimo, M Suematsu, M Tomita BioMed Research International 2010, 2010 | 40 | 2010 |
| Artificial intelligence-based computational framework for drug-target prioritization and inference of novel repositionable drugs for Alzheimer’s disease S Tsuji, T Hase, A Yachie-Kinoshita, T Nishino, S Ghosh, M Kikuchi, ... Alzheimer's Research & Therapy 13 (1), 92, 2021 | 38 | 2021 |
| A simplified method for power-law modelling of metabolic pathways from time-course data and steady-state flux profiles T Kitayama, A Kinoshita, M Sugimoto, Y Nakayama, M Tomita Theoretical Biology and Medical Modelling 3, 1-9, 2006 | 28 | 2006 |
| IQCELL: A platform for predicting the effect of gene perturbations on developmental trajectories using single-cell RNA-seq data T Heydari, M A. Langley, CL Fisher, D Aguilar-Hidalgo, S Shukla, ... PLoS computational biology 18 (2), e1009907, 2022 | 15 | 2022 |
| Disease-related cellular protein networks differentially affected under different EGFR mutations in lung adenocarcinoma T Nishimura, H Nakamura, A Yachie, T Hase, K Fujii, H Koizumi, S Naruki, ... Scientific reports 10 (1), 10881, 2020 | 14 | 2020 |
| LimeMap: a comprehensive map of lipid mediator metabolic pathways A Nishi, K Ohbuchi, N Kaifuchi, C Shimobori, H Kushida, M Yamamoto, ... npj Systems Biology and Applications 7 (1), 6, 2021 | 11 | 2021 |
| Effects of maoto (ma-huang-tang) on host lipid mediator and transcriptome signature in influenza virus infection A Nishi, N Kaifuchi, C Shimobori, K Ohbuchi, S Iizuka, A Sugiyama, ... Scientific reports 11 (1), 4232, 2021 | 8 | 2021 |
| Computational systems biology SK Palaniappan, A Yachie-Kinoshita, S Ghosh Academic Press, 2019 | 7 | 2019 |
| Biomarker results and preclinical rationale for combination lenvatinib and pembrolizumab in advanced endometrial carcinoma. V Makker, AL Cohn, MH Taylor, Y Minoshima, Y Kato, R Dairiki, ... Journal of Clinical Oncology 36 (15_suppl), 5597-5597, 2018 | 7 | 2018 |
