SOX2 promotes tumor metastasis by stimulating epithelial-to-mesenchymal transition via regulation of WNT/β-catenin signal network X Li, Y Xu, Y Chen, S Chen, X Jia, T Sun, Y Liu, X Li, R Xiang, N Li Cancer letters 336 (2), 379-389, 2013 | 212 | 2013 |
CD44 antibody-targeted liposomal nanoparticles for molecular imaging and therapy of hepatocellular carcinoma L Wang, W Su, Z Liu, M Zhou, S Chen, Y Chen, D Lu, Y Liu, Y Fan, ... Biomaterials 33 (20), 5107-5114, 2012 | 206 | 2012 |
SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells S Chen, Y Xu, Y Chen, X Li, W Mou, L Wang, Y Liu, RA Reisfeld, R Xiang, ... PloS one 7 (5), e36326, 2012 | 187 | 2012 |
Legumain: a biomarker for diagnosis and prognosis of human ovarian cancer L Wang, S Chen, M Zhang, N Li, Y Chen, W Su, Y Liu, D Lu, S Li, Y Yang, ... Journal of cellular biochemistry 113 (8), 2679-2686, 2012 | 112 | 2012 |
SOX2 regulates apoptosis through MAP4K4-survivin signaling pathway in human lung cancer cells S Chen, X Li, D Lu, Y Xu, W Mou, L Wang, Y Chen, Y Liu, X Li, LY Li, L Liu, ... Carcinogenesis 35 (3), 613-623, 2014 | 105 | 2014 |
Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity J Xuan, S Chen, B Ning, WH Tolleson, L Guo Chemico-biological interactions 255, 63-73, 2016 | 85 | 2016 |
microRNAs as pharmacogenomic biomarkers for drug efficacy and drug safety assessment I Koturbash, WH Tolleson, L Guo, D Yu, S Chen, H Hong, W Mattes, ... Biomarkers in medicine 9 (11), 1153-1176, 2015 | 78 | 2015 |
Sertraline, an antidepressant, induces apoptosis in hepatic cells through the mitogen-activated protein kinase pathway S Chen, J Xuan, L Wan, H Lin, L Couch, N Mei, VN Dobrovolsky, L Guo Toxicological sciences 137 (2), 404-415, 2014 | 70 | 2014 |
Regulation of cytochrome P450 expression by microRNAs and long noncoding RNAs: Epigenetic mechanisms in environmental toxicology and carcinogenesis D Li, WH Tolleson, D Yu, S Chen, L Guo, W Xiao, W Tong, B Ning Journal of Environmental Science and Health, Part C 37 (3), 180-214, 2019 | 64 | 2019 |
Ginkgo biloba leaf extract induces DNA damage by inhibiting topoisomerase II activity in human hepatic cells Z Zhang, S Chen, H Mei, J Xuan, X Guo, L Couch, VN Dobrovolsky, L Guo, ... Scientific reports 5 (1), 14633, 2015 | 64 | 2015 |
Sertraline induces endoplasmic reticulum stress in hepatic cells S Chen, J Xuan, L Couch, A Iyer, Y Wu, QZ Li, L Guo Toxicology 322, 78-88, 2014 | 64 | 2014 |
MicroRNA hsa-miR-370-3p suppresses the expression and induction of CYP2D6 by facilitating mRNA degradation L Zeng, Y Chen, Y Wang, LR Yu, B Knox, J Chen, T Shi, S Chen, Z Ren, ... Biochemical pharmacology 140, 139-149, 2017 | 63 | 2017 |
Expression of Sox2 in breast cancer cells promotes the recruitment of M2 macrophages to tumor microenvironment W Mou, Y Xu, Y Ye, S Chen, X Li, K Gong, Y Liu, Y Chen, X Li, Y Tian, ... Cancer letters 358 (2), 115-123, 2015 | 61 | 2015 |
Endoplasmic reticulum stress in drug-and environmental toxicant-induced liver toxicity S Chen, WB Melchior Jr, L Guo Journal of Environmental Science and Health, Part C 32 (1), 83-104, 2014 | 59 | 2014 |
STIM1 accelerates cell senescence in a remodeled microenvironment but enhances the epithelial-to-mesenchymal transition in prostate cancer Y Xu, S Zhang, H Niu, Y Ye, F Hu, S Chen, X Li, X Luo, S Jiang, Y Liu, ... Scientific reports 5 (1), 11754, 2015 | 58 | 2015 |
The expression, induction and pharmacological activity of CYP1A2 are post-transcriptionally regulated by microRNA hsa-miR-132-5p Y Chen, L Zeng, Y Wang, WH Tolleson, B Knox, S Chen, Z Ren, L Guo, ... Biochemical pharmacology 145, 178-191, 2017 | 57 | 2017 |
Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans D Yu, L Wu, P Gill, WH Tolleson, S Chen, J Sun, B Knox, Y Jin, W Xiao, ... Archives of toxicology 92, 845-858, 2018 | 53 | 2018 |
Mechanism study of goldenseal-associated DNA damage S Chen, L Wan, L Couch, H Lin, Y Li, VN Dobrovolsky, N Mei, L Guo Toxicology letters 221 (1), 64-72, 2013 | 51 | 2013 |
MicroRNA hsa-miR-25-3p suppresses the expression and drug induction of CYP2B6 in human hepatocytes Y Jin, D Yu, WH Tolleson, B Knox, Y Wang, S Chen, Z Ren, H Deng, ... Biochemical pharmacology 113, 88-96, 2016 | 49 | 2016 |
ROS generation and JNK activation contribute to 4-methoxy-TEMPO-induced cytotoxicity, autophagy, and DNA damage in HepG2 cells Z Zhang, Z Ren, S Chen, X Guo, F Liu, L Guo, N Mei Archives of toxicology 92, 717-728, 2018 | 48 | 2018 |