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SI CHEN
SI CHEN
National Center for Toxicological Research
Verified email at fda.hhs.gov
Title
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Cited by
Year
SOX2 promotes tumor metastasis by stimulating epithelial-to-mesenchymal transition via regulation of WNT/β-catenin signal network
X Li, Y Xu, Y Chen, S Chen, X Jia, T Sun, Y Liu, X Li, R Xiang, N Li
Cancer letters 336 (2), 379-389, 2013
2122013
CD44 antibody-targeted liposomal nanoparticles for molecular imaging and therapy of hepatocellular carcinoma
L Wang, W Su, Z Liu, M Zhou, S Chen, Y Chen, D Lu, Y Liu, Y Fan, ...
Biomaterials 33 (20), 5107-5114, 2012
2062012
SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells
S Chen, Y Xu, Y Chen, X Li, W Mou, L Wang, Y Liu, RA Reisfeld, R Xiang, ...
PloS one 7 (5), e36326, 2012
1872012
Legumain: a biomarker for diagnosis and prognosis of human ovarian cancer
L Wang, S Chen, M Zhang, N Li, Y Chen, W Su, Y Liu, D Lu, S Li, Y Yang, ...
Journal of cellular biochemistry 113 (8), 2679-2686, 2012
1122012
SOX2 regulates apoptosis through MAP4K4-survivin signaling pathway in human lung cancer cells
S Chen, X Li, D Lu, Y Xu, W Mou, L Wang, Y Chen, Y Liu, X Li, LY Li, L Liu, ...
Carcinogenesis 35 (3), 613-623, 2014
1052014
Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity
J Xuan, S Chen, B Ning, WH Tolleson, L Guo
Chemico-biological interactions 255, 63-73, 2016
852016
microRNAs as pharmacogenomic biomarkers for drug efficacy and drug safety assessment
I Koturbash, WH Tolleson, L Guo, D Yu, S Chen, H Hong, W Mattes, ...
Biomarkers in medicine 9 (11), 1153-1176, 2015
782015
Sertraline, an antidepressant, induces apoptosis in hepatic cells through the mitogen-activated protein kinase pathway
S Chen, J Xuan, L Wan, H Lin, L Couch, N Mei, VN Dobrovolsky, L Guo
Toxicological sciences 137 (2), 404-415, 2014
702014
Regulation of cytochrome P450 expression by microRNAs and long noncoding RNAs: Epigenetic mechanisms in environmental toxicology and carcinogenesis
D Li, WH Tolleson, D Yu, S Chen, L Guo, W Xiao, W Tong, B Ning
Journal of Environmental Science and Health, Part C 37 (3), 180-214, 2019
642019
Ginkgo biloba leaf extract induces DNA damage by inhibiting topoisomerase II activity in human hepatic cells
Z Zhang, S Chen, H Mei, J Xuan, X Guo, L Couch, VN Dobrovolsky, L Guo, ...
Scientific reports 5 (1), 14633, 2015
642015
Sertraline induces endoplasmic reticulum stress in hepatic cells
S Chen, J Xuan, L Couch, A Iyer, Y Wu, QZ Li, L Guo
Toxicology 322, 78-88, 2014
642014
MicroRNA hsa-miR-370-3p suppresses the expression and induction of CYP2D6 by facilitating mRNA degradation
L Zeng, Y Chen, Y Wang, LR Yu, B Knox, J Chen, T Shi, S Chen, Z Ren, ...
Biochemical pharmacology 140, 139-149, 2017
632017
Expression of Sox2 in breast cancer cells promotes the recruitment of M2 macrophages to tumor microenvironment
W Mou, Y Xu, Y Ye, S Chen, X Li, K Gong, Y Liu, Y Chen, X Li, Y Tian, ...
Cancer letters 358 (2), 115-123, 2015
612015
Endoplasmic reticulum stress in drug-and environmental toxicant-induced liver toxicity
S Chen, WB Melchior Jr, L Guo
Journal of Environmental Science and Health, Part C 32 (1), 83-104, 2014
592014
STIM1 accelerates cell senescence in a remodeled microenvironment but enhances the epithelial-to-mesenchymal transition in prostate cancer
Y Xu, S Zhang, H Niu, Y Ye, F Hu, S Chen, X Li, X Luo, S Jiang, Y Liu, ...
Scientific reports 5 (1), 11754, 2015
582015
The expression, induction and pharmacological activity of CYP1A2 are post-transcriptionally regulated by microRNA hsa-miR-132-5p
Y Chen, L Zeng, Y Wang, WH Tolleson, B Knox, S Chen, Z Ren, L Guo, ...
Biochemical pharmacology 145, 178-191, 2017
572017
Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans
D Yu, L Wu, P Gill, WH Tolleson, S Chen, J Sun, B Knox, Y Jin, W Xiao, ...
Archives of toxicology 92, 845-858, 2018
532018
Mechanism study of goldenseal-associated DNA damage
S Chen, L Wan, L Couch, H Lin, Y Li, VN Dobrovolsky, N Mei, L Guo
Toxicology letters 221 (1), 64-72, 2013
512013
MicroRNA hsa-miR-25-3p suppresses the expression and drug induction of CYP2B6 in human hepatocytes
Y Jin, D Yu, WH Tolleson, B Knox, Y Wang, S Chen, Z Ren, H Deng, ...
Biochemical pharmacology 113, 88-96, 2016
492016
ROS generation and JNK activation contribute to 4-methoxy-TEMPO-induced cytotoxicity, autophagy, and DNA damage in HepG2 cells
Z Zhang, Z Ren, S Chen, X Guo, F Liu, L Guo, N Mei
Archives of toxicology 92, 717-728, 2018
482018
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