Epigenetic balance of gene expression by Polycomb and COMPASS families A Piunti, A Shilatifard Science 352 (6290), 2016 | 243 | 2016 |
Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas A Piunti, R Hashizume, MA Morgan, ET Bartom, CM Horbinski, ... Nature medicine 23 (4), 493-500, 2017 | 188 | 2017 |
Epigenetic factors in cancer development: polycomb group proteins A Piunti, D Pasini Future oncology 7 (1), 57-75, 2011 | 87 | 2011 |
Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability R Rickels, HM Herz, CC Sze, K Cao, MA Morgan, CK Collings, M Gause, ... Nature genetics 49 (11), 1647, 2017 | 85 | 2017 |
Detection of Histone H3 mutations in cerebrospinal fluid-derived tumor DNA from children with diffuse midline glioma TY Huang, A Piunti, RR Lulla, J Qi, CM Horbinski, T Tomita, CD James, ... Acta neuropathologica communications 5 (1), 28, 2017 | 82 | 2017 |
Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication A Piunti, A Rossi, A Cerutti, M Albert, S Jammula, A Scelfo, L Cedrone, ... Nature communications 5 (1), 1-14, 2014 | 69 | 2014 |
Polycomb complex PRC1 preserves intestinal stem cell identity by sustaining Wnt/β-catenin transcriptional activity F Chiacchiera, A Rossi, SG Jammula, A Piunti, A Scelfo, ... Cell stem cell 18 (1), 91-103, 2016 | 65 | 2016 |
The controversial role of the Polycomb group proteins in transcription and cancer: how much do we not understand Polycomb proteins? A Scelfo, A Piunti, D Pasini The FEBS journal 282 (9), 1703-1722, 2015 | 57 | 2015 |
An evolutionary conserved epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS R Rickels, D Hu, CK Collings, AR Woodfin, A Piunti, M Mohan, HM Herz, ... Molecular cell 63 (2), 318-328, 2016 | 44 | 2016 |
TET2 coactivates gene expression through demethylation of enhancers L Wang, PA Ozark, ER Smith, Z Zhao, SA Marshall, EJ Rendleman, ... Science advances 4 (11), eaau6986, 2018 | 43 | 2018 |
Isolation of chromatin from dysfunctional telomeres reveals an important role for Ring1b in NHEJ-mediated chromosome fusions C Bartocci, JK Diedrich, I Ouzounov, J Li, A Piunti, D Pasini, JR Yates III, ... Cell reports 7 (4), 1320-1332, 2014 | 41 | 2014 |
A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation MAJ Morgan, RA Rickels, CK Collings, X He, K Cao, HM Herz, ... Genes & development 31 (19), 2003-2014, 2017 | 29 | 2017 |
Epigenetic methylations and their connections with metabolism F Chiacchiera, A Piunti, D Pasini Cellular and Molecular Life Sciences 70 (9), 1495-1508, 2013 | 28 | 2013 |
CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism A Piunti, ER Smith, MAJ Morgan, M Ugarenko, N Khaltyan, KA Helmin, ... Science advances 5 (7), eaax2887, 2019 | 23 | 2019 |
PML promotes metastasis of triple-negative breast cancer through transcriptional regulation of HIF1A target genes M Ponente, L Campanini, R Cuttano, A Piunti, GA Delledonne, N Coltella, ... JCI insight 2 (4), 2017 | 23 | 2017 |
Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice A Rossi, KJ Ferrari, A Piunti, SG Jammula, F Chiacchiera, L Mazzarella, ... Science advances 2 (10), e1600972, 2016 | 13 | 2016 |
Radiosensitization by histone H3 demethylase inhibition in diffuse intrinsic pontine glioma H Katagi, N Louis, D Unruh, T Sasaki, X He, A Zhang, Q Ma, A Piunti, ... Clinical Cancer Research 25 (18), 5572-5583, 2019 | 9 | 2019 |
Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation D Douillet, CC Sze, C Ryan, A Piunti, AP Shah, M Ugarenko, SA Marshall, ... Nature Genetics 52 (6), 615-625, 2020 | 8 | 2020 |
Epigenetic mechanisms drive the progression of neurofibromas to malignant peripheral nerve sheath tumors K Suresh, T Kliot, A Piunti, M Kliot Surgical Neurology International 7 (Suppl 33), S797, 2016 | 4 | 2016 |
PDTM-28. TARGETED INHIBITION OF EZH2 AND BET BROMODOMAIN PROTEINS FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMAS A Piunti, M Morgan, E Bartom, N Louis, X He, A Zhang, C Horbinski, ... Neuro-oncology 19 (suppl_6), vi196-vi196, 2017 | 2 | 2017 |