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Elena Sotillo
Elena Sotillo
Stanford Cancer Institute
Geverifieerd e-mailadres voor stanford.edu
Titel
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Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy
E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ...
Cancer discovery 5 (12), 1282-1295, 2015
11802015
c-Jun overexpression in CAR T cells induces exhaustion resistance
RC Lynn, EW Weber, E Sotillo, D Gennert, P Xu, Z Good, H Anbunathan, ...
Nature 576 (7786), 293-300, 2019
5512019
CAR T cells targeting B7-H3, a pan-cancer antigen, demonstrate potent preclinical activity against pediatric solid tumors and brain tumors
RG Majzner, JL Theruvath, A Nellan, S Heitzeneder, Y Cui, CW Mount, ...
Clinical Cancer Research 25 (8), 2560-2574, 2019
4282019
Tuning the antigen density requirement for CAR T-cell activity
RG Majzner, SP Rietberg, E Sotillo, R Dong, VT Vachharajani, ...
Cancer discovery 10 (5), 702-723, 2020
3402020
Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling
EW Weber, KR Parker, E Sotillo, RC Lynn, H Anbunathan, J Lattin, ...
Science 372 (6537), eaba1786, 2021
3372021
Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors
J Theruvath, E Sotillo, CW Mount, CM Graef, A Delaidelli, S Heitzeneder, ...
Nature medicine 26 (5), 712-719, 2020
1962020
Pharmacologic control of CAR-T cell function using dasatinib
EW Weber, RC Lynn, E Sotillo, J Lattin, P Xu, CL Mackall
Blood advances 3 (5), 711-717, 2019
1732019
Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells
DB Rivadeneira, CN Mayhew, C Thangavel, E Sotillo, CA Reed, X Graña, ...
Gastroenterology 138 (5), 1920-1930. e2, 2010
1482010
CAR T cell therapy for neuroblastoma
RM Richards, E Sotillo, RG Majzner
Frontiers in immunology 9, 417699, 2018
1422018
Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication
J Theruvath, M Menard, BAH Smith, MH Linde, GL Coles, GN Dalton, ...
Nature medicine 28 (2), 333-344, 2022
1142022
G1 cyclin/cyclin-dependent kinase-coordinated phosphorylation of endogenous pocket proteins differentially regulates their interactions with E2F4 and E2F1 and gene expression
J Calbó, M Parreno, E Sotillo, T Yong, A Mazo, J Garriga, X Grana
Journal of Biological Chemistry 277 (52), 50263-50274, 2002
1142002
Repeated loss of target surface antigen after immunotherapy in primary mediastinal large B cell lymphoma
H Yu, E Sotillo, C Harrington, G Wertheim, M Paessler, SL Maude, ...
American journal of hematology 92 (1), E11, 2017
1012017
Myc overexpression brings out unexpected antiapoptotic effects of miR-34a
E Sotillo, T Laver, H Mellert, JM Schelter, MA Cleary, S McMahon, ...
Oncogene 30 (22), 2587-2594, 2011
1012011
Enhanced safety and efficacy of protease-regulated CAR-T cell receptors
L Labanieh, RG Majzner, D Klysz, E Sotillo, CJ Fisher, JG Vilches-Moure, ...
Cell 185 (10), 1745-1763. e22, 2022
972022
Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery
SH Chiou, D Tseng, A Reuben, V Mallajosyula, IS Molina, S Conley, ...
Immunity 54 (3), 586-602. e8, 2021
862021
GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity
S Heitzeneder, KR Bosse, Z Zhu, D Zhelev, RG Majzner, MT Radosevich, ...
Cancer Cell 40 (1), 53-69. e9, 2022
822022
Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19
M Asnani, KE Hayer, AS Naqvi, S Zheng, SY Yang, D Oldridge, F Ibrahim, ...
Leukemia 34 (4), 1202-1207, 2020
732020
Shielding the messenger (RNA): microRNA-based anticancer therapies
E Sotillo, A Thomas-Tikhonenko
Pharmacology & therapeutics 131 (1), 18-32, 2011
732011
Co-opting signalling molecules enables logic-gated control of CAR T cells
AM Tousley, MC Rotiroti, L Labanieh, LW Rysavy, WJ Kim, C Lareau, ...
Nature 615 (7952), 507-516, 2023
682023
Genetic and epigenetic alterations of the cell cycle regulators and tumor suppressor genes in pediatric osteosarcomas
A Patiño-García, ES Piñeiro, MZ Díez, LG Iturriagagoitia, FA Klüssmann, ...
Journal of Pediatric Hematology/Oncology 25 (5), 362-367, 2003
672003
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Artikelen 1–20