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Daniel J. McGrail
Daniel J. McGrail
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High tumor mutation burden fails to predict immune checkpoint blockade response across all cancer types
DJ McGrail, PG Pilié, NU Rashid, L Voorwerk, M Slagter, M Kok, ...
Annals of Oncology 32 (5), 661-672, 2021
6782021
Sequential therapy with PARP and WEE1 inhibitors minimizes toxicity while maintaining efficacy
Y Fang, DJ McGrail, C Sun, M Labrie, X Chen, D Zhang, Z Ju, CP Vellano, ...
Cancer cell 35 (6), 851-867. e7, 2019
1802019
Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates
DJ McGrail, J Dai, KM McAndrews, R Kalluri
PloS one 15 (7), e0236619, 2020
1502020
PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma
XD Liu, W Kong, CB Peterson, DJ McGrail, A Hoang, X Zhang, T Lam, ...
Nature communications 11 (1), 2135, 2020
1422020
The malignancy of metastatic ovarian cancer cells is increased on soft matrices through a mechanosensitive Rho–ROCK pathway
DJ McGrail, QMN Kieu, MR Dawson
Journal of cell science 127 (12), 2621-2626, 2014
1282014
Mesenchymal stem cells induce directional migration of invasive breast cancer cells through TGF-β
KM McAndrews, DJ McGrail, N Ravikumar, MR Dawson
Scientific reports 5 (1), 16941, 2015
1042015
Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers
DJ McGrail, L Federico, Y Li, H Dai, Y Lu, GB Mills, S Yi, SY Lin, N Sahni
Nature communications 9 (1), 1317, 2018
982018
Protection against SARS-CoV-2 by BCG vaccination is not supported by epidemiological analyses
J Hensel, KM McAndrews, DJ McGrail, DP Dowlatshahi, VS LeBleu, ...
Scientific reports 10 (1), 1-9, 2020
822020
Proteome instability is a therapeutic vulnerability in mismatch repair-deficient cancer
DJ McGrail, J Garnett, J Yin, H Dai, DJH Shih, TNA Lam, Y Li, C Sun, Y Li, ...
Cancer cell 37 (3), 371-386. e12, 2020
782020
Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets
R Ferrarotto, Y Mitani, DJ McGrail, K Li, TV Karpinets, D Bell, SJ Frank, ...
Clinical Cancer Research, 2020
762020
Alterations in ovarian cancer cell adhesion drive taxol resistance by increasing microtubule dynamics in a FAK-dependent manner
DJ McGrail, NN Khambhati, MX Qi, KS Patel, N Ravikumar, ...
Scientific reports 5 (1), 9529, 2015
762015
Characterization of the immune landscape of EGFR-mutant NSCLC identifies CD73/adenosine pathway as a potential therapeutic target
X Le, MV Negrao, A Reuben, L Federico, L Diao, D McGrail, M Nilsson, ...
Journal of thoracic oncology 16 (4), 583-600, 2021
722021
SNAIL‐induced epithelial‐to‐mesenchymal transition produces concerted biophysical changes from altered cytoskeletal gene expression
DJ McGrail, R Mezencev, QMN Kieu, JF McDonald, MR Dawson
The FASEB Journal 29 (4), 1280-1289, 2015
712015
Distinct tumor-infiltrating lymphocyte landscapes are associated with clinical outcomes in localized non-small-cell lung cancer
L Federico, DJ McGrail, SE Bentebibel, C Haymaker, A Ravelli, MA Forget, ...
Annals of Oncology 33 (1), 42-56, 2022
632022
Neoadjuvant chemotherapy increases cytotoxic T cell, tissue resident memory T cell, and B cell infiltration in resectable NSCLC
PO Gaudreau, MV Negrao, KG Mitchell, A Reuben, EM Corsini, J Li, ...
Journal of Thoracic Oncology 16 (1), 127-139, 2021
632021
Poldip2 controls vascular smooth muscle cell migration by regulating focal adhesion turnover and force polarization
SR Datla, DJ McGrail, S Vukelic, LP Huff, AN Lyle, L Pounkova, M Lee, ...
American Journal of Physiology-Heart and Circulatory Physiology 307 (7 …, 2014
622014
Differential mechanical response of mesenchymal stem cells and fibroblasts to tumor-secreted soluble factors
DJ McGrail, D Ghosh, ND Quach, MR Dawson
PLoS One 7 (3), e33248, 2012
582012
Improved prediction of PARP inhibitor response and identification of synergizing agents through use of a novel gene expression signature generation algorithm
DJ McGrail, CCJ Lin, J Garnett, Q Liu, W Mo, H Dai, Y Lu, Q Yu, Z Ju, J Yin, ...
NPJ systems biology and applications 3 (1), 8, 2017
572017
Revealing the determinants of widespread alternative splicing perturbation in cancer
Y Li, N Sahni, R Pancsa, DJ McGrail, J Xu, X Hua, ...
Cell reports 21 (3), 798-812, 2017
532017
Osmotic regulation is required for cancer cell survival under solid stress
DJ McGrail, KM McAndrews, CP Brandenburg, N Ravikumar, QMN Kieu, ...
Biophysical journal 109 (7), 1334-1337, 2015
522015
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Artikelen 1–20