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Abinaya Chandrasekaran
Abinaya Chandrasekaran
Geverifieerd e-mailadres voor sund.ku.dk
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Neurons derived from sporadic Alzheimer’s disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation
A Ochalek, B Mihalik, HX Avci, A Chandrasekaran, A Téglási, I Bock, ...
Alzheimer's research & therapy 9, 1-19, 2017
1922017
Astrocyte differentiation of human pluripotent stem cells: new tools for neurological disorder research
A Chandrasekaran, HX Avci, M Leist, J Kobolák, A Dinnyés
Frontiers in cellular neuroscience 10, 215, 2016
1722016
Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells
A Chandrasekaran, HX Avci, A Ochalek, LN Rösingh, K Molnár, L László, ...
Stem cell research 25, 139-151, 2017
1222017
Neurosphere based differentiation of human iPSC improves astrocyte differentiation
S Zhou, K Szczesna, A Ochalek, J Kobolák, E Varga, C Nemes, ...
Stem Cells International 2016, 2016
702016
Modeling neurodegenerative diseases with patient-derived induced pluripotent cells: Possibilities and challenges
A Poon, Y Zhang, A Chandrasekaran, P Phanthong, B Schmid, ...
New biotechnology 39, 190-198, 2017
572017
Glutamate-glutamine homeostasis is perturbed in neurons and astrocytes derived from patient iPSC models of frontotemporal dementia
BI Aldana, Y Zhang, P Jensen, A Chandrasekaran, SK Christensen, ...
Molecular Brain 13, 1-17, 2020
482020
Altered neurite morphology and cholinergic function of induced pluripotent stem cell-derived neurons from a patient with Kleefstra syndrome and autism
J Nagy, J Kobolak, S Berzsenyi, Z Abraham, HX Avci, I Bock, Z Bekes, ...
Translational psychiatry 7 (7), e1179-e1179, 2017
372017
Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3
A Chandrasekaran, KS Dittlau, GI Corsi, H Haukedal, NT Doncheva, ...
Stem cell reports 16 (11), 2736-2751, 2021
282021
Golgi fragmentation–One of the earliest organelle phenotypes in Alzheimer’s disease neurons
H Haukedal, GI Corsi, VP Gadekar, NT Doncheva, S Kedia, N de Haan, ...
Frontiers in neuroscience 17, 1120086, 2023
202023
Establishment of induced pluripotent stem cell (iPSC) line from a 63-year old patient with late onset Alzheimer's disease (LOAD)
A Chandrasekaran, E Varga, C Nemes, Z Táncos, J Kobolák, A Dinnyés
Stem Cell Research 17 (1), 78-80, 2016
82016
Neural derivates of canine induced pluripotent stem cells-like cells from a mild cognitive impairment dog
A Chandrasekaran, BB Thomsen, JS Agerholm, LVF Pessôa, ...
Frontiers in veterinary science 8, 725386, 2021
32021
Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3
H Haukedal, SS Lorenzen, EW Westi, GI Corsi, VP Gadekar, A McQuade, ...
Brain, Behavior, and Immunity 113, 353-373, 2023
22023
Generation of three isogenic gene-edited Huntington’s disease human embryonic stem cell lines with DOX-inducible NGN2 expression cassette in the AAVS1 safe locus
LD Villegas, A Chandrasekaran, SAF Andersen, A Nørremølle, B Schmid, ...
Stem Cell Research 77, 103408, 2024
2024
Generation of two patient specific GABRD variants and their isogenic controls for modeling epilepsy
M Kamand, R Taleb, M Wathikthinnakon, FA Mohamed, SP Ghazanfari, ...
Stem Cell Research, 103372, 2024
2024
Generation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Astrocytes for Amyotrophic Lateral Sclerosis and Other Neurodegenerative Disease Studies
KS Dittlau, A Chandrasekaran, K Freude, L Van Den Bosch
Bio-protocol 14 (4), 2024
2024
IDENTIFYING THE ROLE OF DIFFERENTIALLY EXPRESSED MICRORNAS IN SCHIZOPHRENIA DURING NEURODEVELOPMENT
F Mohamed, A Chandrasekaran, M Larsen, K Freude
IBRO Neuroscience Reports 15, S189, 2023
2023
EARLY PATHOLOGICAL CHANGES IN ALZHEIMER’S DISEASE MEDIATED BY ABERRANT MICROGLIA ACTIVITY
M Kadlecova, H Haukedal, A Chandrasekaran, M Larsen, K Freude
IBRO Neuroscience Reports 15, S182, 2023
2023
Generation of eight hiPSCs lines from two pathogenic variants in CACNA1A using the CRISPR-Cas9 gene editing technology
P Rivera-Sánchez, L Søndergaard, M Wathikthinnakon, HBD Magnusson, ...
Stem Cell Research 71, 103193, 2023
2023
Golgi fragmentation–One of the earliest organelle phenotypes in Alzheimer’s disease neurons
Y Liu, JC François, Q Tuo, K Freude, H Haukedal, GI Corsi, VP Gadekar, ...
2023
A protein-centric view of in vitro biological model systems for schizophrenia
A Chandrasekaran, P Jensen, FA Mohamed, M Lancaster, ME Benros, ...
Stem Cells 39 (12), 1569-1578, 2021
2021
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