mTOR: a protein kinase switching between life and death L Asnaghi, P Bruno, M Priulla, A Nicolin Pharmacological research 50 (6), 545-549, 2004 | 366 | 2004 |
Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activities X Qian, G Li, HK Asmussen, L Asnaghi, WC Vass, R Braverman, ... Proceedings of the National Academy of Sciences 104 (21), 9012-9017, 2007 | 176 | 2007 |
Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt L Asnaghi, A Calastretti, A Bevilacqua, I D'Agnano, G Gatti, G Canti, ... Oncogene 23 (34), 5781-5791, 2004 | 160 | 2004 |
Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma K Hu, S Babapoor-Farrokhran, M Rodrigues, M Deshpande, B Puchner, ... Oncotarget 7 (7), 7816, 2016 | 120 | 2016 |
E-cadherin negatively regulates neoplastic growth in non-small cell lung cancer: role of Rho GTPases L Asnaghi, WC Vass, R Quadri, PM Day, X Qian, R Braverman, ... Oncogene 29 (19), 2760-2771, 2010 | 106 | 2010 |
The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis X Qian, G Li, WC Vass, A Papageorge, RC Walker, L Asnaghi, ... Cancer cell 16 (3), 246-258, 2009 | 105 | 2009 |
Induced pluripotent stem cells from familial Alzheimer's disease patients differentiate into mature neurons with amyloidogenic properties V Mahairaki, J Ryu, A Peters, Q Chang, T Li, TS Park, PW Burridge, ... Stem cells and development 23 (24), 2996-3010, 2014 | 93 | 2014 |
Nerve growth factor cooperates with p185 HER2 in activating growth of human breast carcinoma cells E Tagliabue, F Castiglioni, C Ghirelli, M Modugno, L Asnaghi, G Somenzi, ... Journal of Biological Chemistry 275 (8), 5388-5394, 2000 | 85 | 2000 |
Notch signaling promotes growth and invasion in uveal melanoma L Asnaghi, KB Ebrahimi, KC Schreck, EE Bar, ML Coonfield, WR Bell, ... Clinical cancer research 18 (3), 654-665, 2012 | 76 | 2012 |
HIF-1α-targeting acriflavine provides long term survival and radiological tumor response in brain cancer therapy A Mangraviti, T Raghavan, F Volpin, N Skuli, D Gullotti, J Zhou, L Asnaghi, ... Scientific reports 7 (1), 14978, 2017 | 68 | 2017 |
Hypoxia promotes uveal melanoma invasion through enhanced Notch and MAPK activation L Asnaghi, MH Lin, KS Lim, KJ Lim, A Tripathy, M Wendeborn, SL Merbs, ... PloS one 9 (8), e105372, 2014 | 64 | 2014 |
Identifying corneal infections in formalin-fixed specimens using next generation sequencing Z Li, FP Breitwieser, J Lu, AS Jun, L Asnaghi, SL Salzberg, CG Eberhart Investigative ophthalmology & visual science 59 (1), 280-288, 2018 | 62 | 2018 |
The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma H Miyahara, S Yadavilli, M Natsumeda, JA Rubens, L Rodgers, ... Cancer letters 400, 110-116, 2017 | 61 | 2017 |
Rapamycin increases the cellular concentration of the BCL-2 protein and exerts an anti-apoptotic effect A Calastretti, F Rancati, MC Ceriani, L Asnaghi, G Canti, A Nicolin European Journal of Cancer 37 (16), 2121-2128, 2001 | 53 | 2001 |
EMT-associated factors promote invasive properties of uveal melanoma cells L Asnaghi, G Gezgin, A Tripathy, JT Handa, SL Merbs, PA van der Velden, ... Molecular vision 21, 919, 2015 | 50 | 2015 |
βA3/A1-Crystallin controls anoikis-mediated cell death in astrocytes by modulating PI3K/AKT/mTOR and ERK survival pathways through the PKD/Bit1-signaling axis B Ma, T Sen, L Asnaghi, M Valapala, F Yang, S Hose, DS McLeod, Y Lu, ... Cell death & disease 2 (10), e217-e217, 2011 | 43 | 2011 |
ACVR1C/SMAD2 signaling promotes invasion and growth in retinoblastoma L Asnaghi, DT White, N Key, J Choi, A Mahale, H Alkatan, DP Edward, ... Oncogene 38 (12), 2056-2075, 2019 | 42 | 2019 |
Notch3 activation promotes invasive glioma formation in a tissue site-specific manner TJ Pierfelice, KC Schreck, L Dang, L Asnaghi, N Gaiano, CG Eberhart Cancer research 71 (3), 1115-1125, 2011 | 42 | 2011 |
A developmental defect in astrocytes inhibits programmed regression of the hyaloid vasculature in the mammalian eye C Zhang, L Asnaghi, C Gongora, B Patek, S Hose, B Ma, MA Fard, ... European journal of cell biology 90 (5), 440-448, 2011 | 35 | 2011 |
A role for Jag2 in promoting uveal melanoma dissemination and growth L Asnaghi, JT Handa, SL Merbs, JW Harbour, CG Eberhart Investigative ophthalmology & visual science 54 (1), 295-306, 2013 | 34 | 2013 |