CSF-1R inhibition alters macrophage polarization and blocks glioma progression SM Pyonteck, L Akkari, AJ Schuhmacher, RL Bowman, L Sevenich, ... Nature medicine 19 (10), 1264-1272, 2013 | 2280 | 2013 |
Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites D Betel, A Koppal, P Agius, C Sander, C Leslie Genome biology 11, 1-14, 2010 | 1821 | 2010 |
The spectrum kernel: A string kernel for SVM protein classification C Leslie, E Eskin, WS Noble Biocomputing 2002, 564-575, 2001 | 1518 | 2001 |
Mismatch string kernels for SVM protein classification E Eskin, J Weston, W Noble, C Leslie Advances in neural information processing systems 15, 2002 | 1162 | 2002 |
Chromatin states define tumour-specific T cell dysfunction and reprogramming M Philip, L Fairchild, L Sun, EL Horste, S Camara, M Shakiba, AC Scott, ... Nature 545 (7655), 452-456, 2017 | 858 | 2017 |
Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism M Peng, N Yin, S Chhangawala, K Xu, CS Leslie, MO Li Science 354 (6311), 481-484, 2016 | 720 | 2016 |
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs AA Khan, D Betel, ML Miller, C Sander, CS Leslie, DS Marks Nature biotechnology 27 (6), 549-555, 2009 | 661 | 2009 |
Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification RM Samstein, A Arvey, SZ Josefowicz, X Peng, A Reynolds, R Sandstrom, ... Cell 151 (1), 153-166, 2012 | 520 | 2012 |
Transcription factor Foxp3 and its protein partners form a complex regulatory network D Rudra, P Deroos, A Chaudhry, RE Niec, A Arvey, RM Samstein, ... Nature immunology 13 (10), 1010-1019, 2012 | 497 | 2012 |
Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression S Lianoglou, V Garg, JL Yang, CS Leslie, C Mayr Genes & development 27 (21), 2380-2396, 2013 | 475 | 2013 |
Transcriptional basis of mouse and human dendritic cell heterogeneity CC Brown, H Gudjonson, Y Pritykin, D Deep, VP Lavallée, A Mendoza, ... Cell 179 (4), 846-863. e24, 2019 | 468 | 2019 |
Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia KJ Mavrakis, AL Wolfe, E Oricchio, T Palomero, K De Keersmaecker, ... Nature cell biology 12 (4), 372-379, 2010 | 428 | 2010 |
ILC1 confer early host protection at initial sites of viral infection OE Weizman, NM Adams, IS Schuster, C Krishna, Y Pritykin, C Lau, ... Cell 171 (4), 795-808. e12, 2017 | 411 | 2017 |
Evaluation of methods for modeling transcription factor sequence specificity MT Weirauch, A Cote, R Norel, M Annala, Y Zhao, TR Riley, ... Nature biotechnology 31 (2), 126-134, 2013 | 409 | 2013 |
Target mRNA abundance dilutes microRNA and siRNA activity A Arvey, E Larsson, C Sander, CS Leslie, DS Marks Molecular systems biology 6 (1), 363, 2010 | 402 | 2010 |
Analysis of tumour-and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S L Sevenich, RL Bowman, SD Mason, DF Quail, F Rapaport, BT Elie, ... Nature cell biology 16 (9), 876-888, 2014 | 390 | 2014 |
Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting GB Loeb, AA Khan, D Canner, JB Hiatt, J Shendure, RB Darnell, ... Molecular cell 48 (5), 760-770, 2012 | 384 | 2012 |
Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells EP Papapetrou, G Lee, N Malani, M Setty, I Riviere, LMS Tirunagari, ... Nature biotechnology 29 (1), 73-78, 2011 | 372 | 2011 |
Cancer immunosurveillance by tissue-resident innate lymphoid cells and innate-like T cells S Dadi, S Chhangawala, BM Whitlock, RA Franklin, CT Luo, SA Oh, ... Cell 164 (3), 365-377, 2016 | 368 | 2016 |
Ibrutinib resistance in chronic lymphocytic leukemia RR Furman, S Cheng, P Lu, M Setty, AR Perez, A Guo, J Racchumi, G Xu, ... New England Journal of Medicine 370 (24), 2352-2354, 2014 | 367 | 2014 |