Constitutive signaling from an engineered IL7 receptor promotes durable tumor elimination by tumor-redirected T cells T Shum, B Omer, H Tashiro, RL Kruse, DL Wagner, K Parikh, Z Yi, ... Cancer discovery 7 (11), 1238-1247, 2017 | 235 | 2017 |
Treatment of acute myeloid leukemia with T cells expressing chimeric antigen receptors directed to C-type lectin-like molecule 1 H Tashiro, T Sauer, T Shum, K Parikh, M Mamonkin, B Omer, RH Rouce, ... Molecular Therapy 25 (9), 2202-2213, 2017 | 129 | 2017 |
Determinants of chest radiography sensitivity for COVID-19: a multi-institutional study in the United States S Stephanie, T Shum, H Cleveland, SR Challa, A Herring, FL Jacobson, ... Radiology: Cardiothoracic Imaging 2 (5), e200337, 2020 | 85 | 2020 |
Enhanced detection of olefins using ambient ionization mass spectrometry: Ag+ adducts of biologically relevant alkenes AU Jackson, T Shum, E Sokol, A Dill, RG Cooks Analytical and bioanalytical chemistry 399, 367-376, 2011 | 84 | 2011 |
HBsAg-redirected T cells exhibit antiviral activity in HBV-infected human liver chimeric mice RL Kruse, T Shum, H Tashiro, M Barzi, Z Yi, C Whitten-Bauer, X Legras, ... Cytotherapy 20 (5), 697-705, 2018 | 80 | 2018 |
Comprehensive approach for identifying the T cell subset origin of CD3 and CD28 antibody–activated chimeric antigen receptor–modified T cells M Schmueck-Henneresse, B Omer, T Shum, H Tashiro, M Mamonkin, ... The Journal of Immunology 199 (1), 348-362, 2017 | 52 | 2017 |
A homing system targets therapeutic T cells to brain cancer H Samaha, A Pignata, K Fousek, J Ren, FW Lam, F Stossi, J Dubrulle, ... Nature 561 (7723), 331-337, 2018 | 44 | 2018 |
Strategies for enhancing adoptive T-cell immunotherapy against solid tumors using engineered cytokine signaling and other modalities T Shum, RL Kruse, CM Rooney Expert opinion on biological therapy 18 (6), 653-664, 2018 | 34 | 2018 |
Adult and cord blood-derived high-affinity gB-CAR-T cells effectively react against human cytomegalovirus infections H Olbrich, SJ Theobald, C Slabik, L Gerasch, A Schneider, M Mach, ... Human Gene Therapy 31 (7-8), 423-439, 2020 | 30 | 2020 |
In situ liver expression of HBsAg/CD3-bispecific antibodies for HBV immunotherapy RL Kruse, T Shum, X Legras, M Barzi, FP Pankowicz, S Gottschalk, ... Molecular therapy Methods & clinical development 7, 32-41, 2017 | 16 | 2017 |
Chimeric antigen receptor signaling domains differentially regulate proliferation and native T cell receptor function in virus-specific T cells B Omer, PA Castillo, H Tashiro, T Shum, MTA Huynh, M Cardenas, ... Frontiers in medicine 5, 343, 2018 | 15 | 2018 |
A costimulatory CAR improves TCR-based cancer immunotherapy B Omer, MG Cardenas, T Pfeiffer, R Daum, M Huynh, S Sharma, ... Cancer immunology research 10 (4), 512-524, 2022 | 14 | 2022 |
Endoscopic-mediated, biliary hydrodynamic injection mediating clinically relevant levels of gene delivery in pig liver RL Kruse, Y Huang, T Shum, L Bai, H Ding, ZZ Wang, FM Selaru, ... Gastrointestinal endoscopy 94 (6), 1119-1130. e4, 2021 | 5 | 2021 |
A backpack revs up T-cell activity T Shum, HE Heslop Nature Biotechnology 36 (8), 702-703, 2018 | 5 | 2018 |
CAR T cells targeted with a high affinity scFv against the HCMV glycoprotein Gb as adoptive T cell therapy after hematopoietic stem cell transplantation R Stripecke, L Gerasch, S Theobald, BS Sundarasetty, M Mamonkin, ... Blood 128 (22), 5721, 2016 | 4 | 2016 |
Determinants of chest X-Ray sensitivity for COVID-19 S Stephanie, T Shum, H Cleveland, SR Challa, A Herring, FL Jacobson A multi-institutional study in the United States Radiol Cardiothorac Imaging …, 0 | 3 | |
Chimeric antigen receptor therapy with reduced cytotoxicity for viral disease RL Kruse, K Bissig, SMG Gottschalk, TCT Shum US Patent 11,219,646, 2022 | 2 | 2022 |
ESGCT XXV anniversary congress in collaboration with the German Society for Gene Therapy, October 17–20, 2017 Berlin, Germany S Maffioletti Human Gene Therapy 28 (12), A1-A125, 2017 | 2 | 2017 |
Sa1504 SAFETY PROFILE OF LIVER-DIRECTED, NON-VIRAL GENE DELIVERY BY ENDOSCOPIC-MEDIATED HYDRODYNAMIC INJECTION OF THE BILIARY TRACT IN PIGS Y Huang, R Kruse, T Shum, H Ding, C Simsek, J Izzi, Z Wang, ... Gastroenterology 158 (6), S-1314, 2020 | 1 | 2020 |
Retraction note: a homing system targets therapeutic T cells to brain cancer H Samaha, A Pignata, K Fousek, J Ren, FW Lam, F Stossi, J Dubrulle, ... Nature 567 (7746), 132-132, 2019 | 1 | 2019 |