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Thomas Shum
Thomas Shum
The Brigham and Women's Hospital, Harvard Medical School
Verified email at bwh.harvard.edu
Title
Cited by
Cited by
Year
Constitutive signaling from an engineered IL7 receptor promotes durable tumor elimination by tumor-redirected T cells
T Shum, B Omer, H Tashiro, RL Kruse, DL Wagner, K Parikh, Z Yi, ...
Cancer discovery 7 (11), 1238-1247, 2017
2352017
Treatment of acute myeloid leukemia with T cells expressing chimeric antigen receptors directed to C-type lectin-like molecule 1
H Tashiro, T Sauer, T Shum, K Parikh, M Mamonkin, B Omer, RH Rouce, ...
Molecular Therapy 25 (9), 2202-2213, 2017
1292017
Determinants of chest radiography sensitivity for COVID-19: a multi-institutional study in the United States
S Stephanie, T Shum, H Cleveland, SR Challa, A Herring, FL Jacobson, ...
Radiology: Cardiothoracic Imaging 2 (5), e200337, 2020
852020
Enhanced detection of olefins using ambient ionization mass spectrometry: Ag+ adducts of biologically relevant alkenes
AU Jackson, T Shum, E Sokol, A Dill, RG Cooks
Analytical and bioanalytical chemistry 399, 367-376, 2011
842011
HBsAg-redirected T cells exhibit antiviral activity in HBV-infected human liver chimeric mice
RL Kruse, T Shum, H Tashiro, M Barzi, Z Yi, C Whitten-Bauer, X Legras, ...
Cytotherapy 20 (5), 697-705, 2018
802018
Comprehensive approach for identifying the T cell subset origin of CD3 and CD28 antibody–activated chimeric antigen receptor–modified T cells
M Schmueck-Henneresse, B Omer, T Shum, H Tashiro, M Mamonkin, ...
The Journal of Immunology 199 (1), 348-362, 2017
522017
A homing system targets therapeutic T cells to brain cancer
H Samaha, A Pignata, K Fousek, J Ren, FW Lam, F Stossi, J Dubrulle, ...
Nature 561 (7723), 331-337, 2018
442018
Strategies for enhancing adoptive T-cell immunotherapy against solid tumors using engineered cytokine signaling and other modalities
T Shum, RL Kruse, CM Rooney
Expert opinion on biological therapy 18 (6), 653-664, 2018
342018
Adult and cord blood-derived high-affinity gB-CAR-T cells effectively react against human cytomegalovirus infections
H Olbrich, SJ Theobald, C Slabik, L Gerasch, A Schneider, M Mach, ...
Human Gene Therapy 31 (7-8), 423-439, 2020
302020
In situ liver expression of HBsAg/CD3-bispecific antibodies for HBV immunotherapy
RL Kruse, T Shum, X Legras, M Barzi, FP Pankowicz, S Gottschalk, ...
Molecular therapy Methods & clinical development 7, 32-41, 2017
162017
Chimeric antigen receptor signaling domains differentially regulate proliferation and native T cell receptor function in virus-specific T cells
B Omer, PA Castillo, H Tashiro, T Shum, MTA Huynh, M Cardenas, ...
Frontiers in medicine 5, 343, 2018
152018
A costimulatory CAR improves TCR-based cancer immunotherapy
B Omer, MG Cardenas, T Pfeiffer, R Daum, M Huynh, S Sharma, ...
Cancer immunology research 10 (4), 512-524, 2022
142022
Endoscopic-mediated, biliary hydrodynamic injection mediating clinically relevant levels of gene delivery in pig liver
RL Kruse, Y Huang, T Shum, L Bai, H Ding, ZZ Wang, FM Selaru, ...
Gastrointestinal endoscopy 94 (6), 1119-1130. e4, 2021
52021
A backpack revs up T-cell activity
T Shum, HE Heslop
Nature Biotechnology 36 (8), 702-703, 2018
52018
CAR T cells targeted with a high affinity scFv against the HCMV glycoprotein Gb as adoptive T cell therapy after hematopoietic stem cell transplantation
R Stripecke, L Gerasch, S Theobald, BS Sundarasetty, M Mamonkin, ...
Blood 128 (22), 5721, 2016
42016
Determinants of chest X-Ray sensitivity for COVID-19
S Stephanie, T Shum, H Cleveland, SR Challa, A Herring, FL Jacobson
A multi-institutional study in the United States Radiol Cardiothorac Imaging …, 0
3
Chimeric antigen receptor therapy with reduced cytotoxicity for viral disease
RL Kruse, K Bissig, SMG Gottschalk, TCT Shum
US Patent 11,219,646, 2022
22022
ESGCT XXV anniversary congress in collaboration with the German Society for Gene Therapy, October 17–20, 2017 Berlin, Germany
S Maffioletti
Human Gene Therapy 28 (12), A1-A125, 2017
22017
Sa1504 SAFETY PROFILE OF LIVER-DIRECTED, NON-VIRAL GENE DELIVERY BY ENDOSCOPIC-MEDIATED HYDRODYNAMIC INJECTION OF THE BILIARY TRACT IN PIGS
Y Huang, R Kruse, T Shum, H Ding, C Simsek, J Izzi, Z Wang, ...
Gastroenterology 158 (6), S-1314, 2020
12020
Retraction note: a homing system targets therapeutic T cells to brain cancer
H Samaha, A Pignata, K Fousek, J Ren, FW Lam, F Stossi, J Dubrulle, ...
Nature 567 (7746), 132-132, 2019
12019
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