Disulfiram modulated ROS–MAPK and NFκB pathways and targeted breast cancer cells with cancer stem cell-like properties NC Yip, IS Fombon, P Liu, S Brown, V Kannappan, AL Armesilla, B Xu, ... British journal of cancer 104 (10), 1564-1574, 2011 | 427 | 2011 |
Cytotoxic effect of disulfiram/copper on human glioblastoma cell lines and ALDH-positive cancer-stem-like cells P Liu, S Brown, T Goktug, P Channathodiyil, V Kannappan, JP Hugnot, ... British journal of cancer 107 (9), 1488-1497, 2012 | 327 | 2012 |
Synthesis of silver nanoparticles using curcumin-cyclodextrins loaded into bacterial cellulose-based hydrogels for wound dressing applications A Gupta, SM Briffa, S Swingler, H Gibson, V Kannappan, G Adamus, ... Biomacromolecules 21 (5), 1802-1811, 2020 | 277 | 2020 |
Disulfiram targets cancer stem-like cells and reverses resistance and cross-resistance in acquired paclitaxel-resistant triple-negative breast cancer cells P Liu, IS Kumar, S Brown, V Kannappan, PE Tawari, JZ Tang, W Jiang, ... British journal of cancer 109 (7), 1876-1885, 2013 | 193 | 2013 |
Liposome encapsulated Disulfiram inhibits NFκB pathway and targets breast cancer stem cells in vitro and in vivo P Liu, Z Wang, S Brown, V Kannappan, PE Tawari, W Jiang, JM Irache, ... Oncotarget 5 (17), 7471, 2014 | 130 | 2014 |
Disulfiram/copper selectively eradicates AML leukemia stem cells in vitro and in vivo by simultaneous induction of ROS-JNK and inhibition of NF-κB and Nrf2 B Xu, S Wang, R Li, K Chen, L He, M Deng, V Kannappan, J Zha, H Dong, ... Cell death & disease 8 (5), e2797-e2797, 2017 | 122 | 2017 |
A comparative study of three-dimensional printing directions: The degradation and toxicological profile of a PLA/PHA blend JG Ausejo, J Rydz, M Musioł, W Sikorska, M Sobota, J Włodarczyk, ... Polymer degradation and stability 152, 191-207, 2018 | 110 | 2018 |
Production and characterisation of bacterial cellulose hydrogels loaded with curcumin encapsulated in cyclodextrins as wound dressings A Gupta, DJ Keddie, V Kannappan, H Gibson, IR Khalil, M Kowalczuk, ... European Polymer Journal 118, 437-450, 2019 | 106 | 2019 |
Poly lactic-co-glycolic acid controlled delivery of disulfiram to target liver cancer stem-like cells Z Wang, J Tan, C McConville, V Kannappan, PE Tawari, J Brown, J Ding, ... Nanomedicine: Nanotechnology, Biology and Medicine 13 (2), 641-657, 2017 | 91 | 2017 |
The cytotoxic mechanisms of disulfiram and copper (ii) in cancer cells PE Tawari, Z Wang, M Najlah, CW Tsang, V Kannappan, P Liu, ... Toxicology research 4 (6), 1439-1442, 2015 | 91 | 2015 |
Recent advances in repurposing disulfiram and disulfiram derivatives as copper-dependent anticancer agents V Kannappan, M Ali, B Small, G Rajendran, S Elzhenni, H Taj, W Wang, ... Frontiers in Molecular Biosciences 8, 741316, 2021 | 72 | 2021 |
Development of injectable PEGylated liposome encapsulating disulfiram for colorectal cancer treatment M Najlah, A Said Suliman, I Tolaymat, S Kurusamy, V Kannappan, ... Pharmaceutics 11 (11), 610, 2019 | 68 | 2019 |
RBP2 induces stem-like cancer cells by promoting EMT and is a prognostic marker for renal cell carcinoma D Zhou, V Kannappan, X Chen, J Li, X Leng, J Zhang, S Xuan Experimental & molecular medicine 48 (6), e238-e238, 2016 | 58 | 2016 |
Investigation of the key chemical structures involved in the anticancer activity of disulfiram in A549 non-small cell lung cancer cell line K Butcher, V Kannappan, RS Kilari, MR Morris, C McConville, ... BMC cancer 18, 1-12, 2018 | 48 | 2018 |
Genetic analyses of undifferentiated small round cell sarcoma identifies a novel sarcoma subtype with a recurrent CRTC1‐SS18 gene fusion A Alholle, M Karanian, AT Brini, MR Morris, V Kannappan, S Niada, ... The Journal of pathology 245 (2), 186-196, 2018 | 28 | 2018 |
Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption H Zhao, P Shi, M Deng, Z Jiang, Y Li, V Kannappan, W Wang, P Li, B Xu Oncotarget 7 (51), 85515, 2016 | 23 | 2016 |
Interleukin 21 inhibits cancer-mediated FOXP3 induction in naïve human CD4 T cells V Kannappan, K Butcher, M Trela, I Nicholl, W Wang, K Attridge Cancer Immunology, Immunotherapy 66, 637-645, 2017 | 19 | 2017 |
Reply: Cytotoxic effect of disulfiram/copper on human glioblastoma cell lines and ALDH-positive cancer-stem-like cells P Liu, S Brown, P Channathodiyil, V Kannappan, AL Armesilla, JL Darling, ... British journal of cancer 108 (4), 994-994, 2013 | 16 | 2013 |
PLGA–Nano-Encapsulated Disulfiram Inhibits Hypoxia-Induced NF-κB, Cancer Stem Cells, and Targets Glioblastoma In Vitro and In Vivo V Kannappan, Y Liu, Z Wang, K Azar, S Kurusamy, RS Kilari, AL Armesilla, ... Molecular Cancer Therapeutics 21 (8), 1273-1284, 2022 | 9 | 2022 |
Aberrant expression of miR-133a in endothelial cells inhibits angiogenesis by reducing pro-angiogenic but increasing anti-angiogenic gene expression S Ahmed, S Kurusamy, ELS David, K Khan, K Kalyanakrishnan, ... Scientific Reports 12 (1), 14730, 2022 | 6 | 2022 |