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Laksshman Sundaram
Laksshman Sundaram
Graduate Student in Computer Science, Stanford University
Geverifieerd e-mailadres voor stanford.edu
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Predicting the clinical impact of human mutation with deep neural networks
L Sundaram, H Gao, SR Padigepati, JF McRae, Y Li, JA Kosmicki, ...
Nature genetics 50 (8), 1161-1170, 2018
3552018
Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution
AE Trevino, F Müller, J Andersen, L Sundaram, A Kathiria, A Shcherbina, ...
Cell 184 (19), 5053-5069. e23, 2021
2222021
Deep Learning-Based Techniques for Training Deep Convolutional Neural Networks
H Gao, F Kai-How, L Sundaram, JF McRAE
US Patent App. 16/160,903, 2019
772019
Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges
R Daneshjou, Y Wang, Y Bromberg, S Bovo, PL Martelli, G Babbi, ...
Human mutation 38 (9), 1182-1192, 2017
472017
Semantic edge labeling over legal citation graphs
A Sadeghian, L Sundaram, D Wang, W Hamilton, K Branting, C Pfeifer
Proceedings of the workshop on legal text, document, and corpus analytics …, 2016
46*2016
DeepBipolar: Identifying genomic mutations for bipolar disorder via deep learning
S Laksshman, RR Bhat, V Viswanath, X Li
Human mutation 38 (9), 1217-1224, 2017
432017
The landscape of tolerated genetic variation in humans and primates
H Gao, T Hamp, J Ede, JG Schraiber, J McRae, M Singer-Berk, Y Yang, ...
Science 380 (6648), eabn8153, 2023
422023
Semi-supervised learning for training an ensemble of deep convolutional neural networks
L Sundaram, F Kai-How, H Gao, JF McRAE
US Patent 11,798,650, 2023
412023
Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease
M Ameen, L Sundaram, M Shen, A Banerjee, S Kundu, S Nair, ...
Cell 185 (26), 4937-4953. e23, 2022
192022
Deep convolutional neural networks for variant classification
L Sundaram, F Kai-How, H Gao, SR PADIGEPATI, JF McRAE
US Patent 11,315,016, 2022
182022
Stepwise Generation of Human Induced Pluripotent Stem Cell–Derived Cardiac Pericytes to Model Coronary Microvascular Dysfunction
M Shen, C Liu, SR Zhao, A Manhas, L Sundaram, M Ameen, JC Wu
Circulation 147 (6), 515-518, 2023
62023
Identification of constrained sequence elements across 239 primate genomes
LFK Kuderna, JC Ulirsch, S Rashid, M Ameen, L Sundaram, G Hickey, ...
Nature 625 (7996), 735-742, 2024
42024
Transcription factor stoichiometry, motif affinity and syntax regulate single-cell chromatin dynamics during fibroblast reprogramming to pluripotency
S Nair, M Ameen, L Sundaram, A Pampari, J Schreiber, A Balsubramani, ...
bioRxiv, 2023
42023
Deep Learning-Based Techniques for Training Deep Convolutional Neural Networks
H Gao, F Kai-How, L Sundaram, JF McRAE
US Patent App. 16/773,678, 2020
42020
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods
N Null, S Jain, C Bakolitsa, SE Brenner, P Radivojac, J Moult, S Repo, ...
Genome Biology 25 (1), 1-46, 2024
12024
Critical assessment of genome interpretation consortium. CAGI, the critical assessment of genome interpretation, establishes progress and pprospects for computational genetic …
S Jain, C Bakolitsa, EB Steven, P Radivojac, J Moult, S Repo, AH Roger, ...
Genome Biology 22 (22; 25 (1): 53.), 1-46, 2024
2024
Quality detection of variant calling using a machine learning classifier
H Gao, H Tobias, JGJ McMaster-Schraiber, L Sundaram, F Kai-How
US Patent App. 17/952,194, 2023
2023
Variant calling without a target reference genome
H Gao, H Tobias, JGJ McMaster-Schraiber, L Sundaram, F Kai-How
US Patent App. 17/952,192, 2023
2023
Unique mapper tool for excluding regions without one-to-one mapping between a set of two reference genomes
H Gao, H Tobias, JGJ McMaster-Schraiber, L Sundaram, F Kai-How
US Patent App. 17/952,198, 2023
2023
Deep learning-based use of protein contact maps for variant pathogenicity prediction
C Chen, H Gao, LS Sundaram, F Kai-How
US Patent App. 17/876,501, 2023
2023
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Artikelen 1–20