The non-muscle functions of actinins: an update KS Foley, PW Young Biochemical Journal 459 (1), 1-13, 2014 | 232* | 2014 |
Microdamage: a cell transducing mechanism based on ruptured osteocyte processes JG Hazenberg, M Freeley, E Foran, TC Lee, D Taylor Journal of biomechanics 39 (11), 2096-2103, 2006 | 159 | 2006 |
Regulation of protein kinase C function by phosphorylation on conserved and non-conserved sites M Freeley, D Kelleher, A Long Cellular signalling 23 (5), 753-762, 2011 | 148 | 2011 |
L-plastin regulates polarization and migration in chemokine-stimulated human T lymphocytes M Freeley, F O’Dowd, T Paul, D Kashanin, A Davies, D Kelleher, A Long The Journal of Immunology 188 (12), 6357-6370, 2012 | 81 | 2012 |
LFA-1/ICAM-1 ligation in human T cells promotes Th1 polarization through a GSK3β signaling–dependent notch pathway NK Verma, MHU Fazil, ST Ong, MLS Chalasani, JH Low, A Kottaiswamy, ... The Journal of Immunology 197 (1), 108-118, 2016 | 62 | 2016 |
CD44 cross-linking induces protein kinase C-regulated migration of human T lymphocytes A Fanning, Y Volkov, M Freeley, D Kelleher, A Long International immunology 17 (4), 449-458, 2005 | 52 | 2005 |
Phosphorylation of Rab5a protein by protein kinase Cϵ is crucial for T-cell migration ST Ong, M Freeley, J Skubis-Zegadło, MHUT Fazil, D Kelleher, F Fresser, ... Journal of Biological Chemistry 289 (28), 19420-19434, 2014 | 51 | 2014 |
Stimulus-induced phosphorylation of PKC θ at the C-terminal hydrophobic-motif in human T lymphocytes M Freeley, Y Volkov, D Kelleher, A Long Biochemical and biophysical research communications 334 (2), 619-630, 2005 | 36 | 2005 |
Differential modulation of Helicobacter pylori lipopolysaccharide‐mediated TLR2 signaling by individual Pellino proteins SM Smith, M Freeley, PN Moynagh, DP Kelleher Helicobacter 22 (1), e12325, 2017 | 24 | 2017 |
RAB40C regulates RACK1 stability via the ubiquitin–proteasome system JP Day, E Whiteley, M Freeley, A Long, B Malacrida, P Kiely, GS Baillie Future science OA 4 (7), FSO317, 2018 | 23 | 2018 |
A high-content analysis toolbox permits dissection of diverse signaling pathways for T lymphocyte polarization M Freeley, G Bakos, A Davies, D Kelleher, A Long, DJ Dunican Journal of biomolecular screening 15 (5), 541-555, 2010 | 23 | 2010 |
Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion D Petrovic, Z Stamataki, E Dempsey, L Golden‐Mason, M Freeley, ... Hepatology 53 (6), 1846-1853, 2011 | 22 | 2011 |
The hepatitis C envelope 2 protein inhibits LFA-1-transduced protein kinase C signaling for T-lymphocyte migration Y Volkov, A Long, M Freeley, L Golden–Mason, C O’Farrelly, A Murphy, ... Gastroenterology 130 (2), 482-492, 2006 | 21 | 2006 |
CD3ε expression defines functionally distinct subsets of Vδ1 T cells in patients with human immunodeficiency virus infection PJ Dunne, CO Maher, M Freeley, K Dunne, A Petrasca, J Orikiiriza, ... Frontiers in immunology 9, 940, 2018 | 20 | 2018 |
Analysis of dynamic tyrosine phosphoproteome in LFA‐1 triggered migrating t‐cells NK Verma, E Dempsey, M Freeley, CH Botting, A Long, D Kelleher, ... Journal of Cellular Physiology 226 (6), 1489-1498, 2011 | 16 | 2011 |
Loss of PTEN expression does not contribute to PDK-1 activity and PKC activation-loop phosphorylation in Jurkat leukaemic T cells M Freeley, J Park, KJ Yang, RL Wange, Y Volkov, D Kelleher, A Long Cellular signalling 19 (12), 2444-2457, 2007 | 16 | 2007 |
Identification and properties of a novel variant of NBC4 (Na+/HCO3− co-transporter 4) that is predominantly expressed in the choroid plexus H Fukuda, T Hirata, N Nakamura, A Kato, K Kawahara, S Wakabayashi, ... Biochemical Journal 450 (1), 179-187, 2013 | 15 | 2013 |
Altered expression of mir-222 and mir-25 influences diverse gene expression changes in transformed normal and anaplastic thyroid cells, and impacts on MEK and TRAIL protein … ST Aherne, P Smyth, M Freeley, L Smith, C Spillane, J O'leary, O Sheils International Journal of Molecular Medicine 38 (2), 433-445, 2016 | 13 | 2016 |
The two hit hypothesis: an improved method for siRNA-mediated gene silencing in stimulated primary human T cells M Freeley, A Long Journal of immunological methods 396 (1-2), 116-127, 2013 | 13 | 2013 |
Regulating the regulator: phosphorylation of PKC θ in T cells M Freeley, A Long Frontiers in Immunology 3, 32464, 2012 | 13 | 2012 |