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Ken Chen
Ken Chen
Professor of Bioinformatics and Computational Biology, The University of Texas MD Anderson
Geverifieerd e-mailadres voor mdanderson.org - Homepage
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A map of human genome variation from population-scale sequencing
1000 Genomes Project Consortium
Nature 467 (7319), 1061-1073, 2010
87352010
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Cancer Genome Atlas Research Network Tissue source sites: Duke University ...
Nature 455 (7216), 1061-1068, 2008
73132008
The somatic genomic landscape of glioblastoma
CW Brennan, RGW Verhaak, A McKenna, B Campos, H Noushmehr, ...
cell 155 (2), 462-477, 2013
49062013
The immune landscape of cancer
V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ...
Immunity 48 (4), 812-830. e14, 2018
43402018
Somatic mutations affect key pathways in lung adenocarcinoma
L Ding, G Getz, DA Wheeler, ER Mardis, MD McLellan, K Cibulskis, ...
Nature 455 (7216), 1069-1075, 2008
30922008
Recurring mutations found by sequencing an acute myeloid leukemia genome
ER Mardis, L Ding, DJ Dooling, DE Larson, MD McLellan, K Chen, ...
New England Journal of Medicine 361 (11), 1058-1066, 2009
26642009
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
L Ding, TJ Ley, DE Larson, CA Miller, DC Koboldt, JS Welch, JK Ritchey, ...
Nature 481 (7382), 506-510, 2012
25102012
An integrated map of structural variation in 2,504 human genomes
PH Sudmant, T Rausch, EJ Gardner, RE Handsaker, A Abyzov, ...
Nature 526 (7571), 75-81, 2015
23412015
Comprehensive characterization of cancer driver genes and mutations
MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ...
Cell 173 (2), 371-385. e18, 2018
21322018
The origin and evolution of mutations in acute myeloid leukemia
JS Welch, TJ Ley, DC Link, CA Miller, DE Larson, DC Koboldt, ...
Cell 150 (2), 264-278, 2012
18172012
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1650*2020
BreakDancer: an algorithm for high-resolution mapping of genomic structural variation
K Chen, JW Wallis, MD McLellan, DE Larson, JM Kalicki, CS Pohl, ...
Nature methods 6 (9), 677-681, 2009
16252009
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
TJ Ley, ER Mardis, L Ding, B Fulton, MD McLellan, K Chen, D Dooling, ...
Nature 456 (7218), 66-72, 2008
15732008
VarScan: variant detection in massively parallel sequencing of individual and pooled samples
DC Koboldt, K Chen, T Wylie, DE Larson, MD McLellan, ER Mardis, ...
Bioinformatics 25 (17), 2283-2285, 2009
14632009
Genome remodelling in a basal-like breast cancer metastasis and xenograft
LI Ding, MJ Ellis, S Li, DE Larson, K Chen, JW Wallis, CC Harris, ...
Nature 464 (7291), 999-1005, 2010
13502010
Genomic landscape of non-small cell lung cancer in smokers and never-smokers
R Govindan, L Ding, M Griffith, J Subramanian, ND Dees, KL Kanchi, ...
Cell 150 (6), 1121-1134, 2012
13282012
Mapping copy number variation by population-scale genome sequencing
RE Mills, K Walter, C Stewart, RE Handsaker, K Chen, C Alkan, A Abyzov, ...
Nature 470 (7332), 59-65, 2011
12722011
Whole-genome analysis informs breast cancer response to aromatase inhibition
MJ Ellis, L Ding, D Shen, J Luo, VJ Suman, JW Wallis, BA Van Tine, ...
Nature 486 (7403), 353-360, 2012
11982012
Clonal evolution in breast cancer revealed by single nucleus genome sequencing
Y Wang, J Waters, ML Leung, A Unruh, W Roh, X Shi, K Chen, P Scheet, ...
Nature 512 (7513), 155-160, 2014
11392014
Clonal architecture of secondary acute myeloid leukemia
MJ Walter, D Shen, L Ding, J Shao, DC Koboldt, K Chen, DE Larson, ...
New England Journal of Medicine 366 (12), 1090-1098, 2012
9732012
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Artikelen 1–20