Jaclyn Quin
Jaclyn Quin
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Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth
D Drygin, A Lin, J Bliesath, CB Ho, SE O'Brien, C Proffitt, M Omori, ...
Cancer research 71 (4), 1418-1430, 2011
3902011
Targeting the nucleolus for cancer intervention
JE Quin, JR Devlin, D Cameron, KM Hannan, RB Pearson, RD Hannan
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (6), 802-816, 2014
1962014
UBF levels determine the number of active ribosomal RNA genes in mammals
E Sanij, G Poortinga, K Sharkey, S Hung, TP Holloway, J Quin, E Robb, ...
Journal of Cell Biology 183 (7), 1259-1274, 2008
1862008
Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling
J Quin, KT Chan, JR Devlin, DP Cameron, J Diesch, C Cullinane, J Ahern, ...
Oncotarget 7 (31), 49800, 2016
652016
Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population
N Hein, DP Cameron, KM Hannan, NYN Nguyen, CY Fong, J Sornkom, ...
Blood 129 (21), 2882-2895, 2017
422017
The nucleolus and ribosomal genes in aging and senescence
N Hein, E Sanij, J Quin, KM Hannan, A Ganley, RD Hannan
Senescence, 2012
272012
Major transcriptional changes observed in the Fulani, an ethnic group less susceptible to malaria
JE Quin, I Bujila, M Chérif, GS Sanou, Y Qu, MV Homann, A Rolicka, ...
Elife 6, e29156, 2017
202017
Epigenetics and malaria susceptibility/protection: a missing piece of the puzzle
C Arama, JE Quin, B Kouriba, AK Östlund Farrants, M Troye-Blomberg, ...
Frontiers in immunology 9, 1733, 2018
72018
ADAR RNA Modifications, the Epitranscriptome and Innate Immunity
J Quin, J Sedmík, D Vukić, A Khan, LP Keegan, MA O’Connell
Trends in Biochemical Sciences, 2021
12021
What will studies of Fulani individuals naturally exposed to malaria teach us about protective immunity to malaria?
M Troye‐Blomberg, C Arama, J Quin, I Bujila, AK Östlund Farrants
Scandinavian Journal of Immunology 92 (4), e12932, 2020
2020
The chromatin‐remodeling complexes B‐WICH and NuRD regulate ribosomal transcription in response to glucose
A Rolicka, Y Guo, A Gañez Zapater, K Tariq, J Quin, A Vintermist, ...
The FASEB Journal 34 (8), 10818-10834, 2020
2020
The chromatin remodelling complex B-WICH is required for transcriptional activation of the ribosomal transcription by glucose stimulation.
A Rolicka, Y Guo, A Gañez-Zapater, J Quin, A Vintermist, F Sadeghifar, ...
2018
A method of classification and treatment
R Pearson, RD HANNAN, E SANIJ, KE SHEPPARD, KM HANNAN, ...
2017
Investigating the p53-independent responses to inhibition of RNA Polymerase I transcription by CX-5461
J Quin
2017
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Artikelen 1–14