Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain MRP Elmore, AR Najafi, MA Koike, NN Dagher, EE Spangenberg, ... Neuron 82 (2), 380-397, 2014 | 1630 | 2014 |
Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology EE Spangenberg, RJ Lee, AR Najafi, RA Rice, MRP Elmore, ... Brain 139 (4), 1265-1281, 2016 | 621 | 2016 |
Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice NN Dagher, AR Najafi, KMN Kayala, MRP Elmore, TE White, R Medeiros, ... Journal of neuroinflammation 12, 1-14, 2015 | 454 | 2015 |
Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice MRP Elmore, LA Hohsfield, EA Kramár, L Soreq, RJ Lee, ST Pham, ... Aging cell 17 (6), e12832, 2018 | 283 | 2018 |
Elimination of microglia improves cognitive function following cranial irradiation MM Acharya, KN Green, BD Allen, AR Najafi, A Syage, H Minasyan, ... Scientific reports 6 (1), 31545, 2016 | 247 | 2016 |
Microglial repopulation resolves inflammation and promotes brain recovery after injury RA Rice, J Pham, RJ Lee, AR Najafi, BL West, KN Green Glia 65 (6), 931-944, 2017 | 206 | 2017 |
A limited capacity for microglial repopulation in the adult brain AR Najafi, J Crapser, S Jiang, W Ng, A Mortazavi, BL West, KN Green Glia 66 (11), 2385-2396, 2018 | 85 | 2018 |
CSF1 receptor signaling is necessary for microglia viability, which unmasks a cell that rapidly repopulates the microglia-depleted adult brain MRP Elmore, AR Najafi, MA Koike, NN Dagher, EE Spangenberg, ... Neuron 82 (2), 380, 2014 | 76 | 2014 |
'Roid rage in rats? Testosterone effects on aggressive motivation, impulsivity and tyrosine hydroxylase RI Wood, A Armstrong, V Fridkin, V Shah, A Najafi, M Jakowec Physiology & behavior 110, 6-12, 2013 | 63 | 2013 |
Effects of long-term and brain-wide colonization of peripheral bone marrow-derived myeloid cells in the CNS LA Hohsfield, AR Najafi, Y Ghorbanian, N Soni, EE Hingco, SJ Kim, ... Journal of neuroinflammation 17, 1-20, 2020 | 36 | 2020 |
Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave LA Hohsfield, AR Najafi, Y Ghorbanian, N Soni, J Crapser, DXF Velez, ... Elife 10, e66738, 2021 | 28 | 2021 |
Combined Anti-inflammatory and Neuroprotective Treatments Have the Potential to Impact Disease Phenotypes in Cln3−/− Mice MA Tarczyluk-Wells, C Salzlechner, AR Najafi, MJ Lim, D Smith, FM Platt, ... Frontiers in Neurology 10, 963, 2019 | 12 | 2019 |
Testing combinatorial therapies for juvenile Batten disease: Lysosome (2018) J Cooper, M Tarczyluk, A Najafi, C Salzlechner, M Lim, D Pearce, D Smith, ... Molecular Genetics and Metabolism 123 (2), S33, 2018 | 3 | 2018 |
A mouse mutant deficient in both neuronal ceroid lipofuscinosis‐associated proteins CLN3 and TPP1 DE Sleat, W Banach‐Petrosky, KE Larrimore, Y Nemtsova, JA Wiseman, ... Journal of Inherited Metabolic Disease 46 (4), 720-734, 2023 | | 2023 |
Exploring Microglial Homeostasis and Repopulation Dynamics Using Colony-Stimulating Factor 1 Receptor Inhibition AR Najafi University of California, Irvine, 2017 | | 2017 |
Subventricular zone/white matter microglia reconstitute the empty adult microglial 2 niche in 3 LA Hohsfield, AR Najafi, Y Ghorbanian, N Soni, J Kim, AJ Anderson, ... | | |