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Allison Najafi
Allison Najafi
Geverifieerd e-mailadres voor uci.edu
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Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain
MRP Elmore, AR Najafi, MA Koike, NN Dagher, EE Spangenberg, ...
Neuron 82 (2), 380-397, 2014
16302014
Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology
EE Spangenberg, RJ Lee, AR Najafi, RA Rice, MRP Elmore, ...
Brain 139 (4), 1265-1281, 2016
6212016
Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice
NN Dagher, AR Najafi, KMN Kayala, MRP Elmore, TE White, R Medeiros, ...
Journal of neuroinflammation 12, 1-14, 2015
4542015
Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice
MRP Elmore, LA Hohsfield, EA Kramár, L Soreq, RJ Lee, ST Pham, ...
Aging cell 17 (6), e12832, 2018
2832018
Elimination of microglia improves cognitive function following cranial irradiation
MM Acharya, KN Green, BD Allen, AR Najafi, A Syage, H Minasyan, ...
Scientific reports 6 (1), 31545, 2016
2472016
Microglial repopulation resolves inflammation and promotes brain recovery after injury
RA Rice, J Pham, RJ Lee, AR Najafi, BL West, KN Green
Glia 65 (6), 931-944, 2017
2062017
A limited capacity for microglial repopulation in the adult brain
AR Najafi, J Crapser, S Jiang, W Ng, A Mortazavi, BL West, KN Green
Glia 66 (11), 2385-2396, 2018
852018
CSF1 receptor signaling is necessary for microglia viability, which unmasks a cell that rapidly repopulates the microglia-depleted adult brain
MRP Elmore, AR Najafi, MA Koike, NN Dagher, EE Spangenberg, ...
Neuron 82 (2), 380, 2014
762014
'Roid rage in rats? Testosterone effects on aggressive motivation, impulsivity and tyrosine hydroxylase
RI Wood, A Armstrong, V Fridkin, V Shah, A Najafi, M Jakowec
Physiology & behavior 110, 6-12, 2013
632013
Effects of long-term and brain-wide colonization of peripheral bone marrow-derived myeloid cells in the CNS
LA Hohsfield, AR Najafi, Y Ghorbanian, N Soni, EE Hingco, SJ Kim, ...
Journal of neuroinflammation 17, 1-20, 2020
362020
Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave
LA Hohsfield, AR Najafi, Y Ghorbanian, N Soni, J Crapser, DXF Velez, ...
Elife 10, e66738, 2021
282021
Combined Anti-inflammatory and Neuroprotective Treatments Have the Potential to Impact Disease Phenotypes in Cln3−/− Mice
MA Tarczyluk-Wells, C Salzlechner, AR Najafi, MJ Lim, D Smith, FM Platt, ...
Frontiers in Neurology 10, 963, 2019
122019
Testing combinatorial therapies for juvenile Batten disease: Lysosome (2018)
J Cooper, M Tarczyluk, A Najafi, C Salzlechner, M Lim, D Pearce, D Smith, ...
Molecular Genetics and Metabolism 123 (2), S33, 2018
32018
A mouse mutant deficient in both neuronal ceroid lipofuscinosis‐associated proteins CLN3 and TPP1
DE Sleat, W Banach‐Petrosky, KE Larrimore, Y Nemtsova, JA Wiseman, ...
Journal of Inherited Metabolic Disease 46 (4), 720-734, 2023
2023
Exploring Microglial Homeostasis and Repopulation Dynamics Using Colony-Stimulating Factor 1 Receptor Inhibition
AR Najafi
University of California, Irvine, 2017
2017
Subventricular zone/white matter microglia reconstitute the empty adult microglial 2 niche in 3
LA Hohsfield, AR Najafi, Y Ghorbanian, N Soni, J Kim, AJ Anderson, ...
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Artikelen 1–16