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Suresh Kumar Poovathingal
Suresh Kumar Poovathingal
Head of Single Cell & Microfluidics Expertise lab; VIB KU Leuven Center for Brain & Disease Research
Geverifieerd e-mailadres voor kuleuven.be
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A single-cell transcriptome atlas of the aging Drosophila brain
K Davie, J Janssens, D Koldere, M De Waegeneer, U Pech, Ł Kreft, ...
Cell 174 (4), 982-998. e20, 2018
6252018
Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment
A Dirkse, A Golebiewska, T Buder, PV Nazarov, A Muller, S Poovathingal, ...
Nature communications 10 (1), 1787, 2019
4582019
Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signatures
C Sousa, A Golebiewska, SK Poovathingal, T Kaoma, Y Pires‐Afonso, ...
EMBO reports 19 (11), e46171, 2018
2362018
Microglia require CD4 T cells to complete the fetal-to-adult transition
E Pasciuto, OT Burton, CP Roca, V Lagou, WD Rajan, T Theys, ...
Cell 182 (3), 625-640. e24, 2020
2262020
Single-nucleus RNA-Seq is not suitable for detection of microglial activation genes in humans
N Thrupp, CS Frigerio, L Wolfs, NG Skene, N Fattorelli, S Poovathingal, ...
Cell reports 32 (13), 2020
2162020
Stem-cell-derived human microglia transplanted in mouse brain to study human disease
R Mancuso, J Van Den Daele, N Fattorelli, L Wolfs, S Balusu, O Burton, ...
Nature neuroscience 22 (12), 2111-2116, 2019
1952019
Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma
J Wouters, Z Kalender-Atak, L Minnoye, KI Spanier, M De Waegeneer, ...
Nature Cell Biology 22 (8), 986-998, 2020
1652020
Xenotransplanted human cortical neurons reveal species-specific development and functional integration into mouse visual circuits
D Linaro, B Vermaercke, R Iwata, A Ramaswamy, B Libé-Philippot, ...
Neuron 104 (5), 972-986. e6, 2019
1332019
Deceptively simple but simply deceptive–Caenorhabditis elegans lifespan studies: considerations for aging and antioxidant effects
J Gruber, LF Ng, SK Poovathingal, B Halliwell
FEBS letters 583 (21), 3377-3387, 2009
1282009
Decoding gene regulation in the fly brain
J Janssens, S Aibar, II Taskiran, JN Ismail, AE Gomez, G Aughey, ...
Nature 601 (7894), 630-636, 2022
1092022
SCENIC+: single-cell multiomic inference of enhancers and gene regulatory networks
C Bravo González-Blas, S De Winter, G Hulselmans, N Hecker, ...
Nature methods 20 (9), 1355-1367, 2023
1072023
Mitochondria metabolism sets the species-specific tempo of neuronal development
R Iwata, P Casimir, E Erkol, L Boubakar, M Planque, IM Gallego López, ...
Science 379 (6632), eabn4705, 2023
882023
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology
A Golebiewska, AC Hau, A Oudin, D Stieber, YA Yabo, V Baus, ...
Acta Neuropathologica 140, 919-949, 2020
882020
Neural stem cells of Parkinson's disease patients exhibit aberrant mitochondrial morphology and functionality
J Walter, S Bolognin, PMA Antony, SL Nickels, SK Poovathingal, ...
Stem cell reports 12 (5), 878-889, 2019
862019
Global parameter estimation methods for stochastic biochemical systems
SK Poovathingal, R Gunawan
BMC bioinformatics 11, 1-12, 2010
762010
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation
L Yshii, E Pasciuto, P Bielefeld, L Mascali, P Lemaitre, M Marino, J Dooley, ...
Nature immunology 23 (6), 878-891, 2022
692022
Actuation enhances patterning in human neural tube organoids
AR Abdel Fattah, B Daza, G Rustandi, MÁ Berrocal-Rubio, B Gorissen, ...
Nature communications 12 (1), 3192, 2021
582021
Identification of genomic enhancers through spatial integration of single‐cell transcriptomics and epigenomics
C Bravo González‐Blas, XJ Quan, R Duran‐Romaña, II Taskiran, ...
Molecular systems biology 16 (5), e9438, 2020
582020
New insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome
E Tiraboschi, S Martina, W van der Ent, K Grzyb, K Gawel, ...
Epilepsia 61 (3), 549-560, 2020
582020
Stochastic Drift in Mitochondrial DNA Point Mutations: A Novel Perspective Ex Silico
SK Poovathingal, J Gruber, B Halliwell, R Gunawan
PLoS computational biology 5 (11), e1000572, 2009
422009
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