| Pharmacological chaperone for α-crystallin partially restores transparency in cataract models LN Makley, KA McMenimen, BT DeVree, JW Goldman, BN McGlasson, ... Science 350 (6261), 674-677, 2015 | 244 | 2015 |
| Binding of a small molecule at a protein–protein interface regulates the chaperone activity of hsp70–hsp40 S Wisén, EB Bertelsen, AD Thompson, S Patury, P Ung, L Chang, ... ACS chemical biology 5 (6), 611-622, 2010 | 171 | 2010 |
| Imbalance of Hsp70 family variants fosters tau accumulation UK Jinwal, E Akoury, JF Abisambra, JC O'Leary III, AD Thompson, LJ Blair, ... The FASEB Journal 27 (4), 1450-1459, 2013 | 122 | 2013 |
| Fine-tuning multiprotein complexes using small molecules AD Thompson, A Dugan, JE Gestwicki, AK Mapp ACS chemical biology 7 (8), 1311-1320, 2012 | 112 | 2012 |
| Cysteine reactivity distinguishes redox sensing by the heat-inducible and constitutive forms of heat shock protein 70 Y Miyata, JN Rauch, UK Jinwal, AD Thompson, S Srinivasan, CA Dickey, ... Chemistry & biology 19 (11), 1391-1399, 2012 | 95 | 2012 |
| Analysis of the tau-associated proteome reveals that exchange of Hsp70 for Hsp90 is involved in tau degradation AD Thompson, KM Scaglione, J Prensner, AT Gillies, A Chinnaiyan, ... ACS chemical biology 7 (10), 1677-1686, 2012 | 82 | 2012 |
| Mutagenesis reveals the complex relationships between ATPase rate and the chaperone activities of Escherichia coli heat shock protein 70 (Hsp70/DnaK) L Chang, AD Thompson, P Ung, HA Carlson, JE Gestwicki Journal of Biological Chemistry 285 (28), 21282-21291, 2010 | 80 | 2010 |
| The E3 ubiquitin ligase CHIP and the molecular chaperone Hsc70 form a dynamic, tethered complex MC Smith, KM Scaglione, VA Assimon, S Patury, AD Thompson, ... Biochemistry 52 (32), 5354-5364, 2013 | 66 | 2013 |
| Visualization and functional analysis of the oligomeric states of Escherichia coli heat shock protein 70 (Hsp70/DnaK) AD Thompson, SM Bernard, G Skiniotis, JE Gestwicki Cell Stress and Chaperones 17 (3), 313-327, 2012 | 60 | 2012 |
| From genome to drug lead: identification of a small-molecule inhibitor of the SARS virus AJ Dooley, N Shindo, B Taggart, JG Park, YP Pang Bioorganic & medicinal chemistry letters 16 (4), 830-833, 2006 | 57 | 2006 |
| Spatial and Functional Distribution of MYBPC3 Pathogenic Variants and Clinical Outcomes in Patients With Hypertrophic Cardiomyopathy AS Helms, AD Thompson, AA Glazier, N Hafeez, S Kabani, J Rodriguez, ... Circulation: Genomic and Precision Medicine 13 (5), 396-405, 2020 | 51 | 2020 |
| Analysis of the interaction of BCL9 with β-catenin and development of fluorescence polarization and surface plasmon resonance binding assays for this interaction SA Kawamoto, AD Thompson, A Coleska, Z Nikolovska-Coleska, H Yi, ... Biochemistry 48 (40), 9534-9541, 2009 | 45 | 2009 |
| Allelic imbalance and haploinsufficiency in MYBPC3-linked hypertrophic cardiomyopathy AA Glazier, A Thompson, SM Day Pflügers Archiv-European Journal of Physiology 471, 781-793, 2019 | 44 | 2019 |
| Pharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation SM Chafekar, S Wisén, AD Thompson, AL Echeverria, GM Walter, ... ACS chemical biology 7 (9), 1556-1564, 2012 | 43 | 2012 |
| Critical role of the FERM domain in Pyk2 stimulated glioma cell migration CA Lipinski, NL Tran, A Dooley, YP Pang, C Rohl, J Kloss, Z Yang, ... Biochemical and biophysical research communications 349 (3), 939-947, 2006 | 36 | 2006 |
| Molecular chaperones DnaK and DnaJ share predicted binding sites on most proteins in the E. coli proteome SR Srinivasan, AT Gillies, L Chang, AD Thompson, JE Gestwicki Molecular BioSystems 8 (9), 2323-2333, 2012 | 35 | 2012 |
| Translation of New and Emerging Therapies for Genetic Cardiomyopathies AS Helms, AD Thompson, SM Day Basic to Translational Science 7 (1), 70-83, 2022 | 28 | 2022 |
| Identification of Key Hinge Residues Important for Nucleotide-Dependent Allostery in E. coli Hsp70/DnaK PMU Ung, AD Thompson, L Chang, JE Gestwicki, HA Carlson PLoS computational biology 9 (11), e1003279, 2013 | 28 | 2013 |
| Computational prediction of protein subdomain stability in MYBPC3 enables clinical risk stratification in hypertrophic cardiomyopathy and enhances variant interpretation AD Thompson, AS Helms, A Kannan, J Yob, NK Lakdawala, SG Wittekind, ... Genetics in Medicine 23 (7), 1281-1287, 2021 | 10 | 2021 |
| Utilization of Cardiac Rehabilitation Among Cardiac Intensive Care Unit Survivors M Sola, AD Thompson, AB Coe, VD Marshall, MP Thomas, HC Prescott, ... The American journal of cardiology 124 (9), 1478-1483, 2019 | 10 | 2019 |
Jason E. GestwickiUniversity of California San FranciscoVerified email at ucsf.edu
