Andrea D. Thompson
Andrea D. Thompson
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Pharmacological chaperone for α-crystallin partially restores transparency in cataract models
LN Makley, KA McMenimen, BT DeVree, JW Goldman, BN McGlasson, ...
Science 350 (6261), 674-677, 2015
Binding of a small molecule at a protein–protein interface regulates the chaperone activity of hsp70–hsp40
S Wisén, EB Bertelsen, AD Thompson, S Patury, P Ung, L Chang, ...
ACS chemical biology 5 (6), 611-622, 2010
Imbalance of Hsp70 family variants fosters tau accumulation
UK Jinwal, E Akoury, JF Abisambra, JC O'Leary III, AD Thompson, LJ Blair, ...
The FASEB Journal 27 (4), 1450-1459, 2013
Fine-tuning multiprotein complexes using small molecules
AD Thompson, A Dugan, JE Gestwicki, AK Mapp
ACS chemical biology 7 (8), 1311-1320, 2012
Cysteine reactivity distinguishes redox sensing by the heat-inducible and constitutive forms of heat shock protein 70
Y Miyata, JN Rauch, UK Jinwal, AD Thompson, S Srinivasan, CA Dickey, ...
Chemistry & biology 19 (11), 1391-1399, 2012
Mutagenesis reveals the complex relationships between ATPase rate and the chaperone activities of Escherichia coli heat shock protein 70 (Hsp70/DnaK)
L Chang, AD Thompson, P Ung, HA Carlson, JE Gestwicki
Journal of Biological Chemistry 285 (28), 21282-21291, 2010
Analysis of the tau-associated proteome reveals that exchange of Hsp70 for Hsp90 is involved in tau degradation
AD Thompson, KM Scaglione, J Prensner, AT Gillies, A Chinnaiyan, ...
ACS chemical biology 7 (10), 1677-1686, 2012
The E3 ubiquitin ligase CHIP and the molecular chaperone Hsc70 form a dynamic, tethered complex
MC Smith, KM Scaglione, VA Assimon, S Patury, AD Thompson, ...
Biochemistry 52 (32), 5354-5364, 2013
From genome to drug lead: identification of a small-molecule inhibitor of the SARS virus
AJ Dooley, N Shindo, B Taggart, JG Park, YP Pang
Bioorganic & medicinal chemistry letters 16 (4), 830-833, 2006
Visualization and functional analysis of the oligomeric states of Escherichia coli heat shock protein 70 (Hsp70/DnaK)
AD Thompson, SM Bernard, G Skiniotis, JE Gestwicki
Cell Stress and Chaperones 17 (3), 313-327, 2012
Pharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation
SM Chafekar, S Wisén, AD Thompson, AL Echeverria, GM Walter, ...
ACS chemical biology 7 (9), 1556-1564, 2012
Analysis of the interaction of BCL9 with β-catenin and development of fluorescence polarization and surface plasmon resonance binding assays for this interaction
SA Kawamoto, AD Thompson, A Coleska, Z Nikolovska-Coleska, H Yi, ...
Biochemistry 48 (40), 9534-9541, 2009
Critical role of the FERM domain in Pyk2 stimulated glioma cell migration
CA Lipinski, NL Tran, A Dooley, YP Pang, C Rohl, J Kloss, Z Yang, ...
Biochemical and biophysical research communications 349 (3), 939-947, 2006
Molecular chaperones DnaK and DnaJ share predicted binding sites on most proteins in the E. coli proteome
SR Srinivasan, AT Gillies, L Chang, AD Thompson, JE Gestwicki
Molecular BioSystems 8 (9), 2323-2333, 2012
Identification of key hinge residues important for nucleotide-dependent allostery in E. coli Hsp70/DnaK
PMU Ung, AD Thompson, L Chang, JE Gestwicki, HA Carlson
PLoS Comput Biol 9 (11), e1003279, 2013
Allelic imbalance and haploinsufficiency in MYBPC3-linked hypertrophic cardiomyopathy
AA Glazier, A Thompson, SM Day
Pflügers Archiv-European Journal of Physiology 471 (5), 781-793, 2019
Spatial and Functional Distribution of MYBPC3 Pathogenic Variants and Clinical Outcomes in Patients With Hypertrophic Cardiomyopathy
AS Helms, AD Thompson, AA Glazier, N Hafeez, S Kabani, J Rodriguez, ...
Circulation: Genomic and Precision Medicine 13 (5), 396-405, 2020
Rescued diagnostic quality by motion correction of dynamic cardiac positron emission tomography (PET) perfusion images
AD Thompson, EP Ficaro, VL Murthy, RL Weinberg
Journal of Nuclear Cardiology 26 (1), 330-332, 2019
The three cornerstones of chemical biology: innovative probes, new discoveries, and enabling tools
AD Thompson, LN Makley, K McMenimen, JE Gestwicki
ACS chemical biology 7 (5), 791-796, 2012
Utilization of Cardiac Rehabilitation Among Cardiac Intensive Care Unit Survivors
M Sola, AD Thompson, AB Coe, VD Marshall, MP Thomas, HC Prescott, ...
The American journal of cardiology 124 (9), 1478-1483, 2019
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