| Autoantibodies against type I IFNs in patients with life-threatening COVID-19 P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ... Science 370 (6515), eabd4585, 2020 | 2460 | 2020 |
| Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ... Science 370 (6515), eabd4570, 2020 | 2120 | 2020 |
| Cytomegalovirus Infection Drives Adaptive Epigenetic Diversification of NK Cells with Altered Signaling and Effector Function H Schlums, F Cichocki, B Tesi, J Theorell, V Beziat, TD Holmes, H Han, ... Immunity 42 (3), 443-456, 2015 | 724 | 2015 |
| NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs V Béziat, LL Liu, JA Malmberg, MA Ivarsson, E Sohlberg, AT Björklund, ... Blood, The Journal of the American Society of Hematology 121 (14), 2678-2688, 2013 | 532 | 2013 |
| Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 429 | 2021 |
| Human NK cells display major phenotypic and functional changes over the life span M Le Garff‐Tavernier, V Béziat, J Decocq, V Siguret, F Gandjbakhch, ... Aging cell 9 (4), 527-535, 2010 | 340 | 2010 |
| X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science immunology 6 (62), eabl4348, 2021 | 325 | 2021 |
| CMV drives clonal expansion of NKG2C+ NK cells expressing self‐specific KIRs in chronic hepatitis patients V Béziat, O Dalgard, T Asselah, P Halfon, P Bedossa, A Boudifa, ... European journal of immunology 42 (2), 447-457, 2012 | 322 | 2012 |
| Unconventional repertoire profile is imprinted during acute chikungunya infection for natural killer cells polarization toward cytotoxicity C Petitdemange, P Becquart, N Wauquier, V Béziat, P Debré, EM Leroy, ... PLoS pathogens 7 (9), e1002268, 2011 | 307 | 2011 |
| Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells N Marquardt, V Béziat, S Nyström, J Hengst, MA Ivarsson, E Kekäläinen, ... The Journal of Immunology 194 (6), 2467-2471, 2015 | 264 | 2015 |
| NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs V Béziat, B Descours, C Parizot, P Debré, V Vieillard PloS one 5 (8), e11966, 2010 | 248 | 2010 |
| Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans LL Liu, J Landskron, EH Ask, M Enqvist, E Sohlberg, JA Traherne, ... Cell Reports 15 (5), 1088-1099, 2016 | 228 | 2016 |
| Role for early-differentiated natural killer cells in infectious mononucleosis T Azzi, A Lünemann, A Murer, S Ueda, V Béziat, KJ Malmberg, G Staubli, ... Blood, The Journal of the American Society of Hematology 124 (16), 2533-2543, 2014 | 220 | 2014 |
| Class I HLA haplotypes form two schools that educate NK cells in different ways A Horowitz, Z Djaoud, N Nemat-Gorgani, J Blokhuis, HG Hilton, V Béziat, ... Science immunology 1 (3), eaag1672-eaag1672, 2016 | 185 | 2016 |
| CD56brightCD16+ NK cells: a functional intermediate stage of NK cell differentiation V Béziat, D Duffy, SN Quoc, M Le Garff-Tavernier, J Decocq, ... The Journal of Immunology 186 (12), 6753-6761, 2011 | 180 | 2011 |
| A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity V Béziat, J Li, JX Lin, CS Ma, P Li, A Bousfiha, I Pellier, S Zoghi, S Baris, ... Science immunology 3 (24), eaat4956, 2018 | 168 | 2018 |
| Phenotype and function of natural killer cells in systemic lupus erythematosus: Excess interferon‐γ production in patients with active disease B Hervier, V Beziat, J Haroche, A Mathian, P Lebon, P Ghillani‐Dalbin, ... Arthritis & Rheumatism 63 (6), 1698-1706, 2011 | 162 | 2011 |
| Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency R Lévy, S Okada, V Béziat, K Moriya, C Liu, LYA Chai, M Migaud, F Hauck, ... Proceedings of the National Academy of Sciences 113 (51), E8277-E8285, 2016 | 158 | 2016 |
| Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine P Bastard, E Michailidis, HH Hoffmann, M Chbihi, T Le Voyer, J Rosain, ... Journal of Experimental Medicine 218 (4), e20202486, 2021 | 142 | 2021 |
| The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 127 | 2022 |
Jean-Laurent Casanova, MD, PhDProfessor, Rockefeller University; Investigator, Howard Hughes Medical Institute; Head, St. GilesVerified email at rockefeller.edu
