Philip Beachy
Philip Beachy
Professor of Biochemistry, Stanford University
Verified email at stanford.edu
Title
Cited by
Cited by
Year
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
C Chiang, Y Litingtung, E Lee, KE Young, JL Corden, H Westphal, ...
Nature 383 (6599), 407, 1996
32241996
The Hedgehog and Wnt signalling pathways in cancer
J Taipale, PA Beachy
nature 411 (6835), 349, 2001
16982001
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
JK Chen, J Taipale, MK Cooper, PA Beachy
Genes & development 16 (21), 2743-2748, 2002
15382002
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
DM Berman, SS Karhadkar, A Maitra, RM De Oca, MR Gerstenblith, ...
Nature 425 (6960), 846-851, 2003
14942003
Tissue repair and stem cell renewal in carcinogenesis
PA Beachy, SS Karhadkar, DM Berman
Nature 432 (7015), 324-331, 2004
14292004
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
J Taipale, JK Chen, MK Cooper, B Wang, RK Mann, L Milenkovic, ...
Nature 406 (6799), 1005-1009, 2000
14042000
Cholesterol modification of hedgehog signaling proteins in animal development
JA Porter, KE Young, PA Beachy
Science 274 (5285), 255-259, 1996
14041996
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
DN Watkins, DM Berman, SG Burkholder, B Wang, PA Beachy, SB Baylin
Nature 422 (6929), 313-317, 2003
12552003
Hedgehog signalling in prostate regeneration, neoplasia and metastasis
SS Karhadkar, GS Bova, N Abdallah, S Dhara, D Gardner, A Maitra, ...
Nature 431 (7009), 707-712, 2004
12322004
Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
B Wang, JF Fallon, PA Beachy
Cell 100 (4), 423-434, 2000
10442000
Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis
H Roelink, JA Porter, C Chiang, Y Tanabe, DT Chang, PA Beachy, ...
Cell 81 (3), 445-455, 1995
10051995
Small molecule modulation of Smoothened activity
JK Chen, J Taipale, KE Young, T Maiti, PA Beachy
Proceedings of the National Academy of Sciences 99 (22), 14071-14076, 2002
9742002
Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
C Zhao, A Chen, CH Jamieson, M Fereshteh, A Abrahamsson, J Blum, ...
Nature 458 (7239), 776-779, 2009
9632009
Teratogen-mediated inhibition of target tissue response to Shh signaling
MK Cooper, JA Porter, KE Young, PA Beachy
Science 280 (5369), 1603-1607, 1998
9601998
Medulloblastoma growth inhibition by hedgehog pathway blockade
DM Berman, SS Karhadkar, AR Hallahan, JI Pritchard, CG Eberhart, ...
Science 297 (5586), 1559-1561, 2002
9522002
The Hedgehog response network: sensors, switches, and routers
L Lum, PA Beachy
Science 304 (5678), 1755-1759, 2004
9092004
Patched acts catalytically to suppress the activity of Smoothened
J Taipale, MK Cooper, T Maiti, PA Beachy
Nature 418 (6900), 892-896, 2002
8652002
Cancer genetics
BAJ Ponder
Nature 411 (6835), 336-341, 2001
7602001
Molecular genetics of the bithorax complex in Drosophila melanogaster
W Bender, M Akam, F Karch, PA Beachy, M Peifer, P Spierer, EB Lewis, ...
Science 221 (4605), 23-29, 1983
6651983
Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog
JJ Lee, DP von Kessler, S Parks, PA Beachy
Cell 71 (1), 33-50, 1992
6461992
The system can't perform the operation now. Try again later.
Articles 1–20