| Sensitive ELISA detection of amyloid‐β protofibrils in biological samples H Englund, D Sehlin, AS Johansson, LNG Nilsson, P Gellerfors, S Paulie, ... Journal of neurochemistry 103 (1), 334-345, 2007 | 264 | 2007 |
| Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons S Söllvander, E Nikitidou, R Brolin, L Söderberg, D Sehlin, L Lannfelt, ... Molecular Neurodegeneration 11, 1-19, 2016 | 209 | 2016 |
| Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer’s disease D Sehlin, XT Fang, L Cato, G Antoni, L Lannfelt, S Syvänen Nature communications 7 (1), 10759, 2016 | 194 | 2016 |
| Bivalent brain shuttle increases antibody uptake by monovalent binding to the transferrin receptor G Hultqvist, S Syvänen, XT Fang, L Lannfelt, D Sehlin Theranostics 7 (2), 308, 2017 | 165 | 2017 |
| Perspectives on future Alzheimer therapies: amyloid-β protofibrils-a new target for immunotherapy with BAN2401 in Alzheimer’s disease L Lannfelt, C Möller, H Basun, G Osswald, D Sehlin, A Satlin, ... Alzheimer's research & therapy 6, 1-8, 2014 | 152 | 2014 |
| An amyloid-β protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer's disease A Lord, A Gumucio, H Englund, D Sehlin, VS Sundquist, L Söderberg, ... Neurobiology of disease 36 (3), 425-434, 2009 | 127 | 2009 |
| Large aggregates are the major soluble Aβ species in AD brain fractionated with density gradient ultracentrifugation D Sehlin, H Englund, B Simu, M Karlsson, M Ingelsson, F Nikolajeff, ... PloS one 7 (2), e32014, 2012 | 111 | 2012 |
| Efficient and inexpensive transient expression of multispecific multivalent antibodies in Expi293 cells XT Fang, D Sehlin, L Lannfelt, S Syvänen, G Hultqvist Biological procedures online 19, 1-9, 2017 | 88 | 2017 |
| Secretion and uptake of α-synuclein via extracellular vesicles in cultured cells G Gustafsson, C Lööv, E Persson, DF Lázaro, S Takeda, J Bergström, ... Cellular and molecular neurobiology 38, 1539-1550, 2018 | 81 | 2018 |
| Specific uptake of an amyloid-β protofibril-binding antibody-tracer in AβPP transgenic mouse brain K Magnusson, D Sehlin, S Syvänen, MM Svedberg, O Philipson, ... Journal of Alzheimer's Disease 37 (1), 29-40, 2013 | 79 | 2013 |
| Delineating amyloid plaque associated neuronal sphingolipids in transgenic Alzheimer’s disease mice (tgArcSwe) using MALDI imaging mass spectrometry I Kaya, D Brinet, W Michno, S Syvänen, D Sehlin, H Zetterberg, ... ACS chemical neuroscience 8 (2), 347-355, 2017 | 77 | 2017 |
| Astroglial responses to amyloid-beta progression in a mouse model of Alzheimer’s disease M Olsen, X Aguilar, D Sehlin, XT Fang, G Antoni, A Erlandsson, ... Molecular Imaging and Biology 20, 605-614, 2018 | 72 | 2018 |
| Interference from heterophilic antibodies in amyloid-β oligomer ELISAs D Sehlin, S Söllvander, S Paulie, RM Brundin, M Ingelsson, L Lannfelt, ... Journal of Alzheimer's Disease 21 (4), 1295-1301, 2010 | 69 | 2010 |
| Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1–40 deposition underlies plaque polymorphism in progressing Alzheimer’s disease pathology W Michno, S Nyström, P Wehrli, T Lashley, G Brinkmalm, L Guerard, ... Journal of Biological Chemistry 294 (17), 6719-6732, 2019 | 65 | 2019 |
| Engineered antibodies: new possibilities for brain PET? D Sehlin, S Syvänen European journal of nuclear medicine and molecular imaging 46 (13), 2848-2858, 2019 | 63 | 2019 |
| High detection sensitivity with antibody-based PET radioligand for amyloid beta in brain XT Fang, G Hultqvist, SR Meier, G Antoni, D Sehlin, S Syvänen Neuroimage 184, 881-888, 2019 | 61 | 2019 |
| Efficient clearance of Aβ protofibrils in AβPP-transgenic mice treated with a brain-penetrating bifunctional antibody S Syvänen, G Hultqvist, T Gustavsson, A Gumucio, H Laudon, ... Alzheimer's Research & Therapy 10, 1-10, 2018 | 58 | 2018 |
| A bispecific Tribody PET radioligand for visualization of amyloid-beta protofibrils–a new concept for neuroimaging S Syvänen, XT Fang, G Hultqvist, SR Meier, L Lannfelt, D Sehlin Neuroimage 148, 55-63, 2017 | 58 | 2017 |
| Increased inflammatory response in cytomegalovirus seropositive patients with Alzheimer’s disease G Westman, D Berglund, J Widen, M Ingelsson, O Korsgren, L Lannfelt, ... PloS one 9 (5), e96779, 2014 | 53 | 2014 |
| Pharmacokinetics, biodistribution and brain retention of a bispecific antibody-based PET radioligand for imaging of amyloid-β D Sehlin, XT Fang, SR Meier, M Jansson, S Syvänen Scientific Reports 7 (1), 17254, 2017 | 50 | 2017 |
Stina SyvänenProfessor, Public Health and Caring SciencesVerified email at pubcare.uu.se
