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Kian Peng Koh
Kian Peng Koh
Verified email at kuleuven.be
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Year
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
M Tahiliani, KP Koh, Y Shen, WA Pastor, H Bandukwala, Y Brudno, ...
Science 324 (5929), 930-935, 2009
63692009
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
M Ko, Y Huang, AM Jankowska, UJ Pape, M Tahiliani, HS Bandukwala, ...
Nature 468 (7325), 839-843, 2010
14932010
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells
KP Koh, A Yabuuchi, S Rao, Y Huang, K Cunniff, J Nardone, A Laiho, ...
Cell stem cell 8 (2), 200-213, 2011
8592011
Tumour hypoxia causes DNA hypermethylation by reducing TET activity
B Thienpont, J Steinbacher, H Zhao, F D’Anna, A Kuchnio, A Ploumakis, ...
Nature 537 (7618), 63-68, 2016
5802016
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX
M Ko, J An, HS Bandukwala, L Chavez, T Äijö, WA Pastor, MF Segal, H Li, ...
Nature 497 (7447), 122-126, 2013
4372013
Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening
M Boretto, N Maenhoudt, X Luo, A Hennes, B Boeckx, B Bui, R Heremans, ...
Nature cell biology 21 (8), 1041-1051, 2019
3282019
Lineage-specific functions of TET1 in the postimplantation mouse embryo
R Khoueiry, A Sohni, B Thienpont, X Luo, JV Velde, M Bartoccetti, ...
Nature genetics 49 (7), 1061-1072, 2017
1132017
DNA methylation and methylcytosine oxidation in cell fate decisions
KP Koh, A Rao
Current opinion in cell biology 25 (2), 152-161, 2013
1042013
Selective oxidation of 5-methylcytosine by tet-family proteins
A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer
872010
Domain requirements and sequence specificity of DNA binding for the forkhead transcription factor FOXP3
KP Koh, MS Sundrud, A Rao
PloS one 4 (12), e8109, 2009
692009
Dynamic Switching of Active Promoter and Enhancer Domains Regulates Tet1 and Tet2 Expression during Cell State Transitions between Pluripotency and …
A Sohni, M Bartoccetti, R Khoueiry, L Spans, J Vande Velde, L De Troyer, ...
Molecular and cellular biology 35 (6), 1026-1042, 2015
532015
PDGFRα+ cells in embryonic stem cell cultures represent the in vitro equivalent of the pre-implantation primitive endoderm precursors
AL Nigro, A de Jaime-Soguero, R Khoueiry, DS Cho, GM Ferlazzo, ...
Stem Cell Reports 8 (2), 318-333, 2017
302017
Selective oxidation of 5-methylcytosine by TET-family proteins
A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer
US Patent 9,447,452, 2016
272016
Selective oxidation of 5-methylcytosine by TET-family proteins
A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer
US Patent 10,031,131, 2018
232018
Wnt/β-catenin inhibition disrupts carboplatin resistance in isogenic models of triple-negative breast cancer
WA Abreu de Oliveira, S Moens, Y El Laithy, BK van Der Veer, ...
Frontiers in Oncology 11, 705384, 2021
222021
Detection of 5-hydroxymethylcytosine by glycosylation
A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer
US Patent 9,816,986, 2017
222017
Selective oxidation of 5-methylcytosine by tet-family proteins
A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer
US Patent App. 15/440,319, 2017
222017
Selective oxidation of 5-methylcytosine by TET-family proteins
A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer
US Patent 10,533,213, 2020
212020
Selective oxidation of 5-methylcytosine by tet-family proteins
A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer
US Patent App. 15/483,297, 2017
212017
Measuring a level of a 5-hydroxymethylcytosine in a sample from a subject having a cancer or suspected of having cancer
A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer
US Patent 10,041,938, 2018
202018
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