Structure− activity relationships of small phosphopeptides, inhibitors of Grb2 SH2 domain, and their prodrugs WQ Liu, M Vidal, C Olszowy, E Million, C Lenoir, H Dhôtel, C Garbay Journal of medicinal chemistry 47 (5), 1223-1233, 2004 | 49 | 2004 |
Structure-based design of new constrained cyclic agonists of the cholecystokinin CCK-B receptor AGS Blommaert, H Dhôtel, B Ducos, C Durieux, N Goudreau, A Bado, ... Journal of medicinal chemistry 40 (5), 647-658, 1997 | 37 | 1997 |
Cyanine derivative as a suitable marker for thermosensitive in situ gelling delivery systems: In vitro and in vivo validation of a sustained buccal drug delivery N Zeng, J Seguin, PL Destruel, G Dumortier, M Maury, H Dhotel, ... International Journal of Pharmaceutics 534 (1-2), 128-135, 2017 | 36 | 2017 |
Reduced in vitro and in vivo toxicity of siRNA-lipoplexes with addition of polyglutamate A Schlegel, P Bigey, H Dhotel, D Scherman, V Escriou Journal of controlled release 165 (1), 1-8, 2013 | 36 | 2013 |
Self-emulsifying drug delivery system developed by the HLB-RSM approach: characterization by transmission electron microscopy and pharmacokinetic study B Bahloul, MA Lassoued, J Seguin, R Lai-Kuen, H Dhotel, S Sfar, ... International journal of pharmaceutics 487 (1-2), 56-63, 2015 | 29 | 2015 |
Liposomes as gene delivery vectors for human placental cells L Valero, K Alhareth, J Espinoza Romero, W Viricel, J Leblond, A Chissey, ... Molecules 23 (5), 1085, 2018 | 26 | 2018 |
Synthesis and in vitro activities of new non‐peptidic APA Inhibitors N Inguimbert, P Coric, H Dhotel, E Bonnard, C Llorens‐Cortes, N De Mota, ... The Journal of peptide research 65 (2), 175-188, 2005 | 26 | 2005 |
Involvement of D2 dopamine receptors in the opposing effects of two CCK-B agonists in a spatial recognition memory task: role of the anterior nucleus accumbens I Léna, H Dhotel, C Garbay, V Daugé Psychopharmacology 153 (2), 170-179, 2001 | 20 | 2001 |
Development of theranostic cationic liposomes designed for image-guided delivery of nucleic acid HD Do, C Ménager, A Michel, J Seguin, T Korichi, H Dhotel, C Marie, ... Pharmaceutics 12 (9), 854, 2020 | 15 | 2020 |
Designing fisetin nanocrystals for enhanced in cellulo anti-angiogenic and anticancer efficacy P Ma, J Seguin, NK Ly, LC Henríquez, E Plansart, K Hammad, R Gahoual, ... International Journal of Pharmaceutics: X 4, 100138, 2022 | 12 | 2022 |
Fine tuning of mixed ionic and hydrogen bond interactions for plasmid delivery using lipoplexes J Seguin, H Dhotel, R Kai-Luen, M Bessodes, N Mignet European Journal of Pharmaceutics and Biopharmaceutics 90, 63-69, 2015 | 12 | 2015 |
Lipids for nucleic acid delivery: Cationic or neutral lipoplexes, synthesis, and particle formation M Bessodes, H Dhotel, N Mignet Nanotechnology for Nucleic Acid Delivery: Methods and Protocols, 123-139, 2019 | 11 | 2019 |
In vivo properties of thiol inhibitors of the three vasopeptidases NEP, ACE and ECE are improved by introduction of a 7‐azatryptophan in P2′ position N Inguimbert, H Poras, H Dhotel, F Beslot, E Scalbert, C Bennejean, ... The Journal of peptide research 63 (2), 99-107, 2004 | 10 | 2004 |
Synthesis and separation of tritiated inhibitors of aminopeptidase A and their prodrugs N Inguimbert, P Coric, H Dhotel, C Llorens‐Cortes, MC Fournié‐Zaluski, ... Journal of Labelled Compounds and Radiopharmaceuticals: The Official Journal …, 2004 | 9 | 2004 |
Novel perfluorinated triblock amphiphilic copolymers for lipid-shelled microbubble stabilization Y Corvis, S Manta, C Thébault, O Couture, H Dhotel, JP Michel, J Seguin, ... Langmuir 34 (33), 9744-9753, 2018 | 8 | 2018 |
Lipidic spherulites as magnetic resonance imaging contrast agents BT Doan, S Crauste-Manciet, C Bourgaux, H Dhotel, L Jugé, D Brossard, ... New Journal of Chemistry 38 (11), 5190-5197, 2014 | 8 | 2014 |
Unexpected formation of new chiral 3-amino-5-alkyl-2, 5-dihydro-1H-pyrrolin-2-ones from N-Boc-α-amino esters N Inguimbert, H Dhoˆtel, P Coric, BP Roques Tetrahedron letters 46 (20), 3517-3520, 2005 | 7 | 2005 |
Intramolecular Diels-Alder reaction of cyclenic trienes: stereoselectivity and NMR structure determination A Blond, N Platzer, A Guy, H Dhotel, L Serva Bulletin de la Société chimique de France 3 (133), 283-293, 1996 | 6 | 1996 |
Use of mouse model in pharmacokinetic studies of poorly water soluble drugs: Application to fenofibrate B Bahloul, F Safta, MA Lassoued, H Dhotel, J Seguin, N Mignet, S Sfar Journal of Drug Delivery Science and Technology 43, 149-153, 2018 | 5 | 2018 |
Combination of thermal ablation by focused ultrasound, pFAR4-IL-12 transfection and lipidic adjuvant provide a distal immune response HD Do, C Marie, S Bessoles, H Dhotel, J Seguin, B Larrat, BT Doan, ... Exploration of Targeted Anti-tumor Therapy 3 (6), 398, 2022 | 3 | 2022 |