Regulatory roles of conserved intergenic domains in vertebrate Dlx bigene clusters N Ghanem, O Jarinova, A Amores, Q Long, G Hatch, BK Park, ... Genome research 13 (4), 533-543, 2003 | 227 | 2003 |
The proneural determinant MASH1 regulates forebrain Dlx1/2expression through the I12b intergenic enhancer L Poitras, N Ghanem, G Hatch, M Ekker Oxford University Press for The Company of Biologists Limited 134 (9), 1755-1765, 2007 | 130 | 2007 |
Distinct cis-regulatory elements from the Dlx1/Dlx2 locus mark different progenitor cell populations in the ganglionic eminences and different subtypes of adult cortical … N Ghanem, M Yu, J Long, G Hatch, JLR Rubenstein, M Ekker Journal of Neuroscience 27 (19), 5012-5022, 2007 | 119 | 2007 |
Analysis of four DLX homeobox genes in autistic probands SP Hamilton, JM Woo, EJ Carlson, N Ghanem, M Ekker, JLR Rubenstein BMC genetics 6, 1-11, 2005 | 90 | 2005 |
Intergenic enhancers with distinct activities regulate Dlx gene expression in the mesenchyme of the branchial arches BK Park, SM Sperber, A Choudhury, N Ghanem, GT Hatch, PT Sharpe, ... Developmental biology 268 (2), 532-545, 2004 | 65 | 2004 |
The Rb/E2F pathway modulates neurogenesis through direct regulation of the Dlx1/Dlx2 bigene cluster N Ghanem, MG Andrusiak, D Svoboda, SM Al Lafi, LM Julian, ... Journal of Neuroscience 32 (24), 8219-8230, 2012 | 63 | 2012 |
The Retinoblastoma family member p107 regulates the rate of progenitor commitment to a neuronal fate JL Vanderluit, CA Wylie, KA McClellan, N Ghanem, A Fortin, S Callaghan, ... The Journal of cell biology 178 (1), 129-139, 2007 | 63 | 2007 |
Combination of drug and stem cells neurotherapy: potential interventions in neurotrauma and traumatic brain injury K Zibara, N Ballout, S Mondello, N Karnib, N Ramadan, S Omais, ... Neuropharmacology 145, 177-198, 2019 | 46 | 2019 |
Characterization of a distinct subpopulation of striatal projection neurons expressing the Dlx genes in the basal ganglia through the activity of the I56ii enhancer N Ghanem, M Yu, L Poitras, JLR Rubenstein, M Ekker Developmental biology 322 (2), 415-424, 2008 | 46 | 2008 |
CDK2 transcriptional repression is an essential effector in p53-dependent cellular senescence—implications for therapeutic intervention H Zalzali, B Nasr, M Harajly, H Basma, F Ghamloush, S Ghayad, ... Molecular Cancer Research 13 (1), 29-40, 2015 | 32 | 2015 |
RB regulates the production and the survival of newborn neurons in the embryonic and adult dentate gyrus R Vandenbosch, A Clark, BC Fong, S Omais, C Jaafar, D Dugal‐Tessier, ... Hippocampus 26 (11), 1379-1392, 2016 | 24 | 2016 |
Role of the Retinoblastoma protein, Rb, during adult neurogenesis in the olfactory bulb R Naser, R Vandenbosch, S Omais, D Hayek, C Jaafar, S Al Lafi, A Saliba, ... Scientific reports 6 (1), 20230, 2016 | 23 | 2016 |
“Till Death Do Us Part”: a potential irreversible link between aberrant cell cycle control and neurodegeneration in the adult olfactory bulb S Omais, C Jaafar, N Ghanem Frontiers in neuroscience 12, 344142, 2018 | 18 | 2018 |
Role of Rb during neurogenesis and axonal guidance in the developing olfactory system C Jaafar, S Omais, S Al Lafi, N El Jamal, M Noubani, L Skaf, N Ghanem Frontiers in Molecular Neuroscience 9, 81, 2016 | 10 | 2016 |
The Rb/E2F axis is a key regulator of the molecular signatures instructing the quiescent and activated adult neural stem cell state BC Fong, I Chakroun, MA Iqbal, S Paul, J Bastasic, D O’Neil, ... Cell Reports 41 (5), 2022 | 7 | 2022 |
Postnatal neural stem cells in treating traumatic brain injury H Gazalah, S Mantash, N Ramadan, S Al Lafi, S El Sitt, H Darwish, ... Injury Models of the Central Nervous System: Methods and Protocols, 689-710, 2016 | 7 | 2016 |
Exogenous flupirtine as potential treatment for CLN3 disease K Maalouf, J Makoukji, S Saab, NJ Makhoul, AV Carmona, N Kinarivala, ... Cells 9 (8), 1872, 2020 | 5 | 2020 |
Histological Assessment of Cre-loxP Genetic Recombination in the Aging Subventricular Zone of Nestin-CreER T2/Rosa26YFP Mice S Omais, NN Halaby, KJ Habashy, C Jaafar, AT Bejjani, N Ghanem Stem Cells and Aging 2, 1-13, 2019 | 3 | 2019 |
Rb deficiency, neuronal survival and neurodegeneration: In search of the perfect mouse model S Omais, YE El Atie, N Ghanem Current Research in Neurobiology 4, 100074, 2023 | 1 | 2023 |
Aging entails distinct requirements for Rb at maintaining adult neurogenesis S Omais, RN Hilal, NN Halaby, C Jaafar, N Ghanem Aging Brain 2, 100041, 2022 | 1 | 2022 |