Stein Aerts
Stein Aerts
Professor @ University of Leuven; VIB Group Leader
Verified email at - Homepage
TitleCited byYear
Gene prioritization through genomic data fusion
S Aerts, D Lambrechts, S Maity, P Van Loo, B Coessens, F De Smet, ...
Nature biotechnology 24 (5), 537, 2006
Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures
A Stark, MF Lin, P Kheradpour, JS Pedersen, L Parts, JW Carlson, ...
Nature 450 (7167), 219, 2007
iRegulon: from a gene list to a gene regulatory network using large motif and track collections
A Verfaillie, H Imrichová, B Van de Sande, L Standaert, V Christiaens, ...
PLoS computational biology 10 (7), e1003731, 2014
Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia
K De Keersmaecker, ZK Atak, N Li, C Vicente, S Patchett, T Girardi, ...
Nature Genetics, 2012
Alteration of the microRNA network during the progression of Alzheimer's disease
P Lau, K Bossers, E Salta, CS Frigerio, S Barbash, R Rothman, ...
EMBO molecular medicine 5 (10), 1613-1634, 2013
E ndeavour update: a web resource for gene prioritization in multiple species
LC Tranchevent, R Barriot, S Yu, S Van Vooren, P Van Loo, B Coessens, ...
Nucleic acids research 36 (suppl_2), W377-W384, 2008
ORegAnno: an open-access community-driven resource for regulatory annotation
OL Griffith, SB Montgomery, B Bernier, B Chu, K Kasaian, S Aerts, ...
Nucleic acids research 36 (suppl_1), D107-D113, 2007
Toucan: deciphering the cis ‐regulatory logic of coregulated genes
S Aerts, G Thijs, B Coessens, M Staes, Y Moreau, BD Moor
Nucleic acids research 31 (6), 1753-1764, 2003
Comparison and meta-analysis of microarray data: from the bench to the computer desk
Y Moreau, S Aerts, B De Moor, B De Strooper, M Dabrowski
TRENDS in Genetics 19 (10), 570-577, 2003
Melanoma addiction to the long non-coding RNA SAMMSON
E Leucci, R Vendramin, M Spinazzi, P Laurette, M Fiers, J Wouters, ...
Nature 531 (7595), 518, 2016
SCENIC: single-cell regulatory network inference and clustering
S Aibar, CB González-Blas, T Moerman, H Imrichova, G Hulselmans, ...
Nature methods 14 (11), 1083, 2017
TOUCAN 2: the all-inclusive open source workbench for regulatory sequence analysis
S Aerts, P Van Loo, G Thijs, H Mayer, R De Martin, Y Moreau, B De Moor
Nucleic acids research 33 (suppl_2), W393-W396, 2005
Computational detection of cis -regulatory modules
S Aerts, P Van Loo, G Thijs, Y Moreau, B De Moor
Bioinformatics 19 (suppl_2), ii5-ii14, 2003
p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity
C Adriaens, L Standaert, J Barra, M Latil, A Verfaillie, P Kalev, B Boeckx, ...
Nature medicine 22 (8), 861, 2016
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state
A Verfaillie, H Imrichova, ZK Atak, M Dewaele, F Rambow, G Hulselmans, ...
Nature communications 6, 6683, 2015
Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia
ZK Atak, V Gianfelici, G Hulselmans, K De Keersmaecker, AG Devasia, ...
PLoS genetics 9 (12), e1003997, 2013
Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation
KK Youssef, G Lapouge, K Bouvrée, S Rorive, S Brohée, O Appelstein, ...
Nature cell biology 14 (12), 1282, 2012
Phenotype molding of stromal cells in the lung tumor microenvironment
D Lambrechts, E Wauters, B Boeckx, S Aibar, D Nittner, O Burton, ...
Nature medicine 24 (8), 1277, 2018
Discovery of transcription factors and regulatory regions driving in vivo tumor development by ATAC-seq and FAIRE-seq open chromatin profiling
K Davie, J Jacobs, M Atkins, D Potier, V Christiaens, G Halder, S Aerts
PLoS genetics 11 (2), e1004994, 2015
JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model
S Degryse, CE De Bock, L Cox, S Demeyer, O Gielen, N Mentens, ...
Blood 124 (20), 3092-3100, 2014
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