Frederic Kaye
Frederic Kaye
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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
JG Paez, PA Jänne, JC Lee, S Tracy, H Greulich, S Gabriel, P Herman, ...
Science 304 (5676), 1497-1500, 2004
The landscape of somatic copy-number alteration across human cancers
R Beroukhim, CH Mermel, D Porter, G Wei, S Raychaudhuri, J Donovan, ...
Nature 463 (7283), 899-905, 2010
Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer
TS Mok, YL Wu, MJ Ahn, MC Garassino, HR Kim, SS Ramalingam, ...
New England Journal of Medicine 376 (7), 629-640, 2017
High-throughput oncogene mutation profiling in human cancer
RK Thomas, AC Baker, RM DeBiasi, W Winckler, T LaFramboise, WM Lin, ...
Nature genetics 39 (3), 347-351, 2007
Abnormalities in structure and expression of the human retinoblastoma gene in SCLC
JW Harbour, SL Lai, J Whang-Peng, AF Gazdar, JD Minna, FJ Kaye
Science 241 (4863), 353-357, 1988
Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells
JM Horowitz, SH Park, E Bogenmann, JC Cheng, DW Yandell, FJ Kaye, ...
Proceedings of the National Academy of Sciences 87 (7), 2775-2779, 1990
Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product
WG Kaelin Jr, DC Pallas, JA DeCaprio, FJ Kaye, DM Livingston
Cell 64 (3), 521-532, 1991
A randomized trial comparing combination electron-beam radiation and chemotherapy with topical therapy in the initial treatment of mycosis fungoides
FJ Kaye, PA Bunn Jr, SM Steinberg, JL Stocker, DC Ihde, AB Fischmann, ...
New England Journal of Medicine 321 (26), 1784-1790, 1989
t (11; 19)(q21; p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway
G Tonon, S Modi, L Wu, A Kubo, AB Coxon, T Komiya, K O'Neil, K Stover, ...
Nature genetics 33 (2), 208-213, 2003
Absence of p16INK4 protein is restricted to the subset of lung cancer lines that retains wildtype RB.
GA Otterson, RA Kratzke, A Coxon, YW Kim, FJ Kaye
Oncogene 9 (11), 3375-3378, 1994
Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity
SN Khleif, J DeGregori, CL Yee, GA Otterson, FJ Kaye, JR Nevins, ...
Proceedings of the National Academy of Sciences 93 (9), 4350-4354, 1996
Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth
WR Sellers, BG Novitch, S Miyake, A Heith, GA Otterson, FJ Kaye, ...
Genes & development 12 (1), 95-106, 1998
Histopathologic staging at initial diagnosis of mycosis fungoides and the Sézary syndrome: definition of three distinctive prognostic groups
EA Sausville, JL Eddy, RW Makuch, AB Fischmann, GP Schechter, ...
Annals of internal medicine 109 (5), 372-382, 1988
CDKN2 gene silencing in lung cancer by DNA hypermethylation and kinetics of p16INK4 protein induction by 5-aza 2'deoxycytidine.
GA Otterson, SN Khleif, W Chen, AB Coxon, FJ Kaye
Oncogene 11 (6), 1211-1216, 1995
A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding
FJ Kaye, RA Kratzke, JL Gerster, JM Horowitz
Proceedings of the National Academy of Sciences 87 (17), 6922-6926, 1990
Thymidylate synthase as an oncogene: a novel role for an essential DNA synthesis enzyme
L Rahman, D Voeller, M Rahman, S Lipkowitz, C Allegra, JC Barrett, ...
Cancer cell 5 (4), 341-351, 2004
CRTC1/MAML2 fusion transcript in high grade mucoepidermoid carcinomas of salivary and thyroid glands and Warthin's tumors: Implications for histogenesis and …
Y Tirado, MD Williams, EY Hanna, FJ Kaye, JG Batsakis, AK El‐Naggar
Genes, Chromosomes and Cancer 46 (7), 708-715, 2007
Immunohistochemical Analysis of the p16INK4 Cyclin-Dependent Kinase Inhibitor in Malignant Mesothelioma
RA Kratzke, GA Otterson, CE Lincoln, S Ewing, H Oie, J Geradts, FJ Kaye
JNCI: Journal of the National Cancer Institute 87 (24), 1870-1875, 1995
RB and cyclin dependent kinase pathways: defining a distinction between RB and p16 loss in lung cancer
FJ Kaye
Oncogene 21 (45), 6908-6914, 2002
RB protein status and clinical correlation from 171 cell lines representing lung cancer, extrapulmonary small cell carcinoma, and mesothelioma.
E Shimizu, A Coxon, GA Otterson, SM Steinberg, RA Kratzke, YW Kim, ...
Oncogene 9 (9), 2441-2448, 1994
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