David DeNardo
David DeNardo
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Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy
DG DeNardo, DJ Brennan, E Rexhepaj, B Ruffell, SL Shiao, SF Madden, ...
Cancer discovery 1 (1), 54-67, 2011
13202011
CD4+ T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
DG DeNardo, JB Barreto, P Andreu, L Vasquez, D Tawfik, N Kolhatkar, ...
Cancer cell 16 (2), 91-102, 2009
11812009
CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models
Y Zhu, BL Knolhoff, MA Meyer, TM Nywening, BL West, J Luo, ...
Cancer research 74 (18), 5057-5069, 2014
6802014
Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression
DG DeNardo, LM Coussens
Breast Cancer Research 9 (4), 212, 2007
6512007
Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses
JB Mitchem, DJ Brennan, BL Knolhoff, BA Belt, Y Zhu, DE Sanford, ...
Cancer research 73 (3), 1128-1141, 2013
6192013
Interactions between lymphocytes and myeloid cells regulate pro-versus anti-tumor immunity
DG DeNardo, P Andreu, LM Coussens
Cancer and Metastasis Reviews 29 (2), 309-316, 2010
5262010
FcRγ activation regulates inflammation-associated squamous carcinogenesis
P Andreu, M Johansson, NI Affara, F Pucci, T Tan, S Junankar, L Korets, ...
Cancer cell 17 (2), 121-134, 2010
4672010
Macrophage expression of hypoxia-inducible factor-1α suppresses T-cell function and promotes tumor progression
AL Doedens, C Stockmann, MP Rubinstein, D Liao, N Zhang, ...
Cancer research 70 (19), 7465-7475, 2010
4502010
Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy
H Jiang, S Hegde, BL Knolhoff, Y Zhu, JM Herndon, MA Meyer, ...
Nature medicine 22 (8), 851-860, 2016
4152016
Immune cells as mediators of solid tumor metastasis
DG DeNardo, M Johansson, LM Coussens
Cancer and Metastasis Reviews 27 (1), 11-18, 2008
3742008
Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: a role for targeting the CCL2/CCR2 axis
DE Sanford, BA Belt, RZ Panni, A Mayer, AD Deshpande, D Carpenter, ...
Clinical cancer research 19 (13), 3404-3415, 2013
3002013
Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a …
TM Nywening, A Wang-Gillam, DE Sanford, BA Belt, RZ Panni, ...
The lancet oncology 17 (5), 651-662, 2016
2802016
MRI of tumor-associated macrophages with clinically applicable iron oxide nanoparticles
HE Daldrup-Link, D Golovko, B Ruffell, DG DeNardo, R Castaneda, ...
Clinical Cancer Research 17 (17), 5695-5704, 2011
2312011
Lymphocytes in cancer development: polarization towards pro-tumor immunity
B Ruffell, DG DeNardo, NI Affara, LM Coussens
Cytokine & growth factor reviews 21 (1), 3-10, 2010
2172010
Tissue-resident macrophages in pancreatic ductal adenocarcinoma originate from embryonic hematopoiesis and promote tumor progression
Y Zhu, JM Herndon, DK Sojka, KW Kim, BL Knolhoff, C Zuo, DR Cullinan, ...
Immunity 47 (2), 323-338. e6, 2017
2162017
Macrophages as regulators of tumour immunity and immunotherapy
DG DeNardo, B Ruffell
Nature Reviews Immunology 19 (6), 369-382, 2019
2132019
Polarized immune responses differentially regulate cancer development
M Johansson, DG DeNardo, LM Coussens
Immunological reviews 222 (1), 145-154, 2008
2092008
TH2-polarized CD4+ T cells and macrophages limit efficacy of radiotherapy
SL Shiao, B Ruffell, DG DeNardo, BA Faddegon, CC Park, LM Coussens
Cancer immunology research 3 (5), 518-525, 2015
183*2015
Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discov. 2011; 1: 54–67. doi: 10.1158/2159-8274
DG DeNardo, DJ Brennan, E Rexhepaj, B Ruffell, SL Shiao, SF Madden, ...
PubMed PubMedCentral, 54-67, 2001
1702001
A framework for advancing our understanding of cancer-associated fibroblasts
E Sahai, I Astsaturov, E Cukierman, DG DeNardo, M Egeblad, RM Evans, ...
Nature Reviews Cancer, 1-13, 2020
1472020
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Artikelen 1–20