Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias K Blinova, J Stohlman, J Vicente, D Chan, L Johannesen, ... Toxicological Sciences 155 (1), 234-247, 2017 | 244 | 2017 |
The use of ratiometric fluorescence measurements of the voltage sensitive dye Di-4-ANEPPS to examine action potential characteristics and drug effects on human induced … MP Hortigon-Vinagre, V Zamora, FL Burton, J Green, GA Gintant, ... Toxicological Sciences 154 (2), 320-331, 2016 | 99 | 2016 |
Gene therapy with angiotensin-(1-9) preserves left ventricular systolic function after myocardial infarction C Fattah, K Nather, CS McCarroll, MP Hortigon-Vinagre, V Zamora, ... Journal of the American College of Cardiology 68 (24), 2652-2666, 2016 | 50 | 2016 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin induces apoptosis by disruption of intracellular calcium homeostasis in human neuronal cell line SHSY5Y A Morales-Hernández, FJ Sánchez-Martín, MP Hortigón-Vinagre, ... Apoptosis 17 (11), 1170-1181, 2012 | 47 | 2012 |
Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology CL Lei, K Wang, M Clerx, RH Johnstone, MP Hortigon-Vinagre, V Zamora, ... Frontiers in physiology 8, 986, 2017 | 46 | 2017 |
Deconvoluting kinase inhibitor induced cardiotoxicity SD Lamore, E Ahlberg, S Boyer, ML Lamb, MP Hortigon-Vinagre, ... Toxicological Sciences 158 (1), 213-226, 2017 | 38 | 2017 |
Targeted disruption of the heat shock protein 20–phosphodiesterase 4D (PDE4D) interaction protects against pathological cardiac remodelling in a mouse model of hypertrophy TP Martin, MP Hortigon-Vinagre, JE Findlay, C Elliott, S Currie, GS Baillie FEBS Open Bio 4, 923-927, 2014 | 35 | 2014 |
Application of optical action potentials in human induced pluripotent stem cells-derived cardiomyocytes to predict drug-induced cardiac arrhythmias HR Lu, MP Hortigon-Vinagre, V Zamora, I Kopljar, A De Bondt, ... Journal of pharmacological and toxicological methods 87, 53-67, 2017 | 33 | 2017 |
Electrophysiological characterization of drug response in hSC-derived cardiomyocytes using voltage-sensitive optical platforms ER Pfeiffer-Kaushik, GL Smith, B Cai, GT Dempsey, MP Hortigon-Vinagre, ... Journal of pharmacological and toxicological methods 99, 106612, 2019 | 31 | 2019 |
Bioactive Phytochemicals from Mercurialis spp. Used in Traditional Spanish Medicine J Blanco-Salas, FM Vazquez, MP Hortigón-Vinagre, T Ruiz-Tellez Plants 8 (7), 193, 2019 | 17 | 2019 |
Correlation between human ether‐a‐go‐go‐related gene channel inhibition and action potential prolongation P Saxena, MP Hortigon‐Vinagre, S Beyl, I Baburin, S Andranovits, ... British journal of pharmacology 174 (18), 3081-3093, 2017 | 14 | 2017 |
Inhibition by 4-hydroxynonenal (HNE) of Ca2+ transport by SERCA1a: Low concentrations of HNE open protein-mediated leaks in the membrane MP Hortigón-Vinagre, S Chardonnet, C Montigny, Y Gutiérrez-Martín, ... Free Radical Biology and Medicine 50 (11), 1700-1713, 2011 | 13 | 2011 |
Thymbra capitata essential oil prevents cell death induced by 4-hydroxy-2-nonenal in neonatal rat cardiac myocytes MP Hortigón-Vinagre, J Blanco, T Ruiz, F Henao Planta medica 80 (15), 1284-1290, 2014 | 12 | 2014 |
Exercise training reveals micro-RNAs associated with improved cardiac function and electrophysiology in rats with heart failure after myocardial infarction TO Stølen, MA Høydal, MS Ahmed, K Jørgensen, K Garten, ... Journal of Molecular and Cellular Cardiology 148, 106-119, 2020 | 11 | 2020 |
Apoptotic cell death in cultured cardiomyocytes following exposure to low concentrations of 4-hydroxy-2-nonenal MP Hortigón-Vinagre, F Henao Cardiovascular toxicology 14 (3), 275-287, 2014 | 10 | 2014 |
The use of voltage sensitive dye di-4-ANEPPS and video-based contractility measurements to assess drug effects on excitation-contraction coupling in human induced pluripotent … MP Hortigon-Vinagre, V Zamora, FL Burton, GL Smith Journal of Cardiovascular Pharmacology, 2020 | 9 | 2020 |
Measurements of voltage, intracellular Ca2+ and contraction from spontaneous iPSC-derived cardiomyocytes using CellOPTIQ® platform reveals complex effects from drugs that … MP Hortigon-Vinagre, V Zamora, FL Burton, P Butler, GL Smith J. Pharmacol. Toxicol. Methods 93, 119-20, 2018 | 4 | 2018 |
Optical measurements of electrical activity from hiPSC-derived cardiomyocytes is a robust and high-throughput method for measuring NCE-effects on the cardiac action potential G Smith, MA Craig, B Anson, M Hortigon-Vinagre, F Burton, R Wallis, ... SOT Annual Meeting, 2013 | 2 | 2013 |
The influence of fibroblast co-culture and 3D structures on cardiac action potentials of human stem cell derived cardiomyocytes. MP Hortigon-Vinagre, V Zamora, G Gintant, EK Gallen, J Green, FL Burton, ... Journal of Pharmacological and Toxicological Methods 93, 169-169, 2018 | 1 | 2018 |
Characterization of electrical and mechanical functions of Pluricyte® hiPSC-derived cardiomyocytes using the optical platform CellOPTIQ® MP Hortigon-Vinagre, V Zamora, T de Korte, M Vlaming, S Braam, ... Journal of Pharmacological and Toxicological Methods 88, 238-239, 2017 | 1 | 2017 |