| Allosteric coupling from G protein to the agonist-binding pocket in GPCRs BT DeVree, JP Mahoney, GA Vélez-Ruiz, SGF Rasmussen, AJ Kuszak, ... Nature 535 (7610), 182-186, 2016 | 258 | 2016 |
| Assembly of a GPCR-G protein complex Y Du, NM Duc, SGF Rasmussen, D Hilger, X Kubiak, L Wang, J Bohon, ... Cell 177 (5), 1232-1242. e11, 2019 | 184 | 2019 |
| Structural and functional analysis of a β2-adrenergic receptor complex with GRK5 KE Komolov, Y Du, NM Duc, RM Betz, JP Rodrigues, RD Leib, D Patra, ... Cell 169 (3), 407-421. e16, 2017 | 154 | 2017 |
| Structural insights into the process of GPCR-G protein complex formation X Liu, X Xu, D Hilger, P Aschauer, JKS Tiemann, Y Du, H Liu, K Hirata, ... Cell 177 (5), 1243-1251. e12, 2019 | 142 | 2019 |
| β-arrestin–biased signaling through the β2-adrenergic receptor promotes cardiomyocyte contraction R Carr III, J Schilling, J Song, RL Carter, Y Du, SM Yoo, CJ Traynham, ... Proceedings of the National Academy of Sciences 113 (28), E4107-E4116, 2016 | 117 | 2016 |
| Development and Characterization of Pepducins as Gs-biased Allosteric Agonists*♦ R Carr, Y Du, J Quoyer, RA Panettieri, JM Janz, M Bouvier, BK Kobilka, ... Journal of Biological Chemistry 289 (52), 35668-35684, 2014 | 96 | 2014 |
| Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes P Xiao, W Yan, L Gou, YN Zhong, L Kong, C Wu, X Wen, Y Yuan, S Cao, ... Cell 184 (4), 943-956. e18, 2021 | 92 | 2021 |
| Physics-informed machine learning and mechanistic modeling of additive manufacturing to reduce defects Y Du, T Mukherjee, T DebRoy Applied Materials Today 24, 101123, 2021 | 74 | 2021 |
| Local membrane charge regulates β2 adrenergic receptor coupling to Gi3 MJ Strohman, S Maeda, D Hilger, M Masureel, Y Du, BK Kobilka Nature Communications 10 (1), 2234, 2019 | 74 | 2019 |
| The α-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the β2-Adrenergic Receptor. BJL Tian X, Irannejad R, Bowman SL, Du Y, Puthenveedu MA, Zastrow M Journal of Biological Chemistry, 2016 | 67 | 2016 |
| Structure-based discovery of nonopioid analgesics acting through the α2A-adrenergic receptor EA Fink, J Xu, H Hübner, JM Braz, P Seemann, C Avet, V Craik, D Weikert, ... Science 377 (6614), eabn7065, 2022 | 64 | 2022 |
| Highly branched pentasaccharide-bearing amphiphiles for membrane protein studies M Ehsan, Y Du, NJ Scull, E Tikhonova, J Tarrasch, JS Mortensen, ... Journal of the American Chemical Society 138 (11), 3789-3796, 2016 | 59 | 2016 |
| Effective application of bicelles for conformational analysis of G protein-coupled receptors by hydrogen/deuterium exchange mass spectrometry NM Duc, Y Du, TS Thorsen, SY Lee, C Zhang, H Kato, BK Kobilka, ... Journal of the American Society for Mass Spectrometry 26 (5), 808-817, 2015 | 57 | 2015 |
| Structures of the substrate-binding protein provide insights into the multiple compatible solute binding specificities of the Bacillus subtilis ABC transporter OpuC Y Du, WW Shi, YX He, YH Yang, CZ Zhou, Y Chen Biochemical Journal 436 (2), 283-289, 2011 | 57 | 2011 |
| Conformationally preorganized diastereomeric norbornane-based maltosides for membrane protein study: Implications of detergent kink for micellar properties M Das, Y Du, O Ribeiro, P Hariharan, JS Mortensen, D Patra, G Skiniotis, ... Journal of the American Chemical Society 139 (8), 3072-3081, 2017 | 49 | 2017 |
| High capacity lossless data hiding in JPEG bitstream based on general VLC mapping Y Du, Z Yin, X Zhang IEEE Transactions on Dependable and Secure Computing 19 (2), 1420-1433, 2020 | 46 | 2020 |
| Accessible Mannitol‐Based Amphiphiles (MNAs) for Membrane Protein Solubilisation and Stabilisation H Hussain, Y Du, NJ Scull, JS Mortensen, J Tarrasch, HE Bae, CJ Loland, ... Chemistry–A European Journal 22 (21), 7068-7073, 2016 | 46 | 2016 |
| Predicting mutational effects on receptor binding of the spike protein of SARS-CoV-2 variants C Bai, J Wang, G Chen, H Zhang, K An, P Xu, Y Du, RD Ye, A Saha, ... Journal of the American Chemical Society 143 (42), 17646-17654, 2021 | 43 | 2021 |
| Structural mechanism underlying primary and secondary coupling between GPCRs and the Gi/o family HR Kim, J Xu, S Maeda, NM Duc, D Ahn, Y Du, KY Chung Nature Communications 11 (1), 3160, 2020 | 42 | 2020 |
| A gradient of sitewise diversity promotes evolutionary fitness for binder discovery in a three-helix bundle protein scaffold DR Woldring, PV Holec, LA Stern, Y Du, BJ Hackel Biochemistry 56 (11), 1656-1671, 2017 | 40 | 2017 |
