Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha BN Chorley, MR Campbell, X Wang, M Karaca, D Sambandan, F Bangura, ... Nucleic acids research 40 (15), 7416-7429, 2012 | 585 | 2012 |
Nrf2-regulated PPARγ expression is critical to protection against acute lung injury in mice HY Cho, W Gladwell, X Wang, B Chorley, D Bell, SP Reddy, ... American journal of respiratory and critical care medicine 182 (2), 170-182, 2010 | 244 | 2010 |
Discovery and verification of functional single nucleotide polymorphisms in regulatory genomic regions: current and developing technologies BN Chorley, X Wang, MR Campbell, GS Pittman, MA Noureddine, DA Bell Mutation Research/Reviews in Mutation Research 659 (1-2), 147-157, 2008 | 243 | 2008 |
Identification of polymorphic antioxidant response elements in the human genome X Wang, DJ Tomso, BN Chorley, HY Cho, VG Cheung, SR Kleeberger, ... Human molecular genetics 16 (10), 1188-1200, 2007 | 198 | 2007 |
Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase Cδ-mediated mechanism JA Park, F He, LD Martin, Y Li, BN Chorley, KB Adler The American journal of pathology 167 (3), 651-661, 2005 | 138 | 2005 |
Applying'omics technologies in chemicals risk assessment: Report of an ECETOC workshop R Buesen, BN Chorley, B da Silva Lima, G Daston, L Deferme, T Ebbels, ... Regulatory Toxicology and Pharmacology 91, S3-S13, 2017 | 120 | 2017 |
Novel hematopoietic target genes in the NRF2-mediated transcriptional pathway MR Campbell, M Karaca, KN Adamski, BN Chorley, X Wang, DA Bell Oxidative medicine and cellular longevity 2013, 2013 | 107 | 2013 |
Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer X Wang, BN Chorley, GS Pittman, SR Kleeberger, J Brothers, G Liu, ... PloS one 5 (8), e11934, 2010 | 70 | 2010 |
Tipping the balance: hepatotoxicity and the 4 apical key events of hepatic steatosis MM Angrish, JP Kaiser, CA McQueen, BN Chorley Toxicological Sciences 150 (2), 261-268, 2016 | 67 | 2016 |
MicroRNA biomarkers of toxicity in biological matrices AH Harrill, SD McCullough, CE Wood, JJ Kahle, BN Chorley Toxicological Sciences 152 (2), 264-272, 2016 | 60 | 2016 |
Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology JA Harrill, MR Viant, CL Yauk, M Sachana, TW Gant, SS Auerbach, ... Regulatory Toxicology and Pharmacology 125, 105020, 2021 | 56 | 2021 |
Probing the functional impact of sequence variation on p53-DNA interactions using a novel microsphere assay for protein-DNA binding with human cell extracts MA Noureddine, D Menendez, MR Campbell, OJ Bandele, MM Horvath, ... PLoS genetics 5 (5), e1000462, 2009 | 51 | 2009 |
A polymorphic antioxidant response element links NRF2/sMAF binding to enhanced MAPT expression and reduced risk of Parkinsonian disorders X Wang, MR Campbell, SE Lacher, HY Cho, M Wan, CL Crowl, ... Cell reports 15 (4), 830-842, 2016 | 48 | 2016 |
Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor J Rooney, K Oshida, N Vasani, B Vallanat, N Ryan, BN Chorley, X Wang, ... PloS one 13 (8), e0200004, 2018 | 47 | 2018 |
Epigenetic applications in adverse outcome pathways and environmental risk evaluation MM Angrish, P Allard, SD McCullough, IL Druwe, L Helbling Chadwick, ... Environmental Health Perspectives 126 (4), 045001, 2018 | 44 | 2018 |
Enhanced expression of mucin genes in a guinea pig model of allergic asthma Y Li, LD Martin, M Minnicozzi, S Greenfeder, J Fine, CA Pettersen, ... American journal of respiratory cell and molecular biology 25 (5), 644-651, 2001 | 44 | 2001 |
Moving toward integrating gene expression profiling into high-throughput testing: A gene expression biomarker accurately predicts estrogen receptor α modulation in a microarray … N Ryan, B Chorley, RR Tice, R Judson, JC Corton Toxicological Sciences 151 (1), 88-103, 2016 | 43 | 2016 |
Framework for the quality assurance of’omics technologies considering GLP requirements HM Kauffmann, H Kamp, R Fuchs, BN Chorley, L Deferme, T Ebbels, ... Regulatory Toxicology and Pharmacology 91, S27-S35, 2017 | 38 | 2017 |
Editor’s highlight: mechanistic toxicity tests based on an adverse outcome pathway network for hepatic steatosis MM Angrish, CA McQueen, E Cohen-Hubal, M Bruno, Y Ge, BN Chorley Toxicological Sciences 159 (1), 159-169, 2017 | 38 | 2017 |
A generic transcriptomics reporting framework (TRF) for ‘omics data processing and analysis TW Gant, UG Sauer, SD Zhang, BN Chorley, J Hackermüller, ... Regulatory Toxicology and Pharmacology 91, S36-S45, 2017 | 36 | 2017 |