| A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse PM Nolan, J Peters, M Strivens, D Rogers, J Hagan, N Spurr, IC Gray, ... Nature genetics 25 (4), 440-443, 2000 | 757 | 2000 |
| Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse JA Curtin, E Quint, V Tsipouri, RM Arkell, B Cattanach, AJ Copp, ... Current Biology 13 (13), 1129-1133, 2003 | 711 | 2003 |
| Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse JN Murdoch, DJ Henderson, K Doudney, C Gaston-Massuet, HM Phillips, ... Human molecular genetics 12 (2), 87-98, 2003 | 348 | 2003 |
| Stabilization of Xist RNA mediates initiation of X chromosome inactivation SA Sheardown, SM Duthie, CM Johnston, AET Newall, EJ Formstone, ... Cell 91 (1), 99-107, 1997 | 308 | 1997 |
| An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse ME Blewitt, NK Vickaryous, SJ Hemley, A Ashe, TJ Bruxner, JI Preis, ... Proceedings of the National Academy of Sciences 102 (21), 7629-7634, 2005 | 211 | 2005 |
| Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling P Ybot-Gonzalez, C Gaston-Massuet, G Girdler, J Klingensmith, R Arkell, ... Oxford University Press for The Company of Biologists Limited 134 (17), 3203 …, 2007 | 191 | 2007 |
| Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues D Garrick, JA Sharpe, R Arkell, L Dobbie, AJH Smith, WG Wood, ... PLoS genetics 2 (4), e58, 2006 | 178 | 2006 |
| Zic2 is required for neural crest formation and hindbrain patterning during mouse development P Elms, P Siggers, D Napper, A Greenfield, R Arkell Developmental biology 264 (2), 391-406, 2003 | 153 | 2003 |
| BMP-7 influences pattern and growth of the developing hindbrain of mouse embryos R Arkell, RSP Beddington Development 124 (1), 1-12, 1997 | 147 | 1997 |
| Expression of inhibin subunits and follistatin during postimplantation mouse development: decidual expression of activin and expression of follistatin in primitive streak … RM Albano, R Arkell, RSP Beddington, JC Smith Development 120 (4), 803-813, 1994 | 146 | 1994 |
| Induction of the mammalian node requires Arkadia function in the extraembryonic lineages V Episkopou, R Arkell, PM Timmons, JJ Walsh, RL Andrew, D Swan Nature 410 (6830), 825-830, 2001 | 126 | 2001 |
| Sexually dimorphic expression of protease nexin-1 and vanin-1 in the developing mouse gonad prior to overt differentiation suggests a role in mammalian sexual development S Grimmond, NV Hateren, P Siggers, R Arkell, R Larder, MB Soares, ... Human Molecular Genetics 9 (10), 1553-1560, 2000 | 122 | 2000 |
| APOE* E2 allele delays age of onset in PSEN1 E280A Alzheimer’s disease JI Vélez, F Lopera, D Sepulveda-Falla, HR Patel, AS Johar, A Chuah, ... Molecular psychiatry 21 (7), 916-924, 2016 | 121 | 2016 |
| Zic2 -associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation N Warr, N Powles-Glover, A Chappell, J Robson, D Norris, RM Arkell Human molecular genetics 17 (19), 2986-2996, 2008 | 113 | 2008 |
| The ZIC gene family encodes multi-functional proteins essential for patterning and morphogenesis R Houtmeyers, J Souopgui, S Tejpar, R Arkell Cellular and Molecular Life Sciences 70, 3791-3811, 2013 | 104 | 2013 |
| Cloning, Mapping, and Expression Analysis of a Gene Encoding a Novel Mammalian EGF-Related Protein (SCUBE1) S Grimmond, R Larder, N Van Hateren, P Siggers, TJM Hulsebos, ... Genomics 70 (1), 74-81, 2000 | 104 | 2000 |
| In vitro analysis of partial loss-of-function ZIC2 mutations in holoprosencephaly: alanine tract expansion modulates DNA binding and transactivation L Brown, M Paraso, R Arkell, S Brown Human molecular genetics 14 (3), 411-420, 2005 | 102 | 2005 |
| Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo SM Harrison, SL Dunwoodie, RM Arkell, H Lehrach, RSP Beddington Development 121 (8), 2479-2489, 1995 | 87 | 1995 |
| Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation P Elms, A Scurry, J Davies, C Willoughby, T Hacker, D Bogani, R Arkell Gene Expression Patterns 4 (5), 505-511, 2004 | 85 | 2004 |
| Flightless I regulates hemidesmosome formation and integrin-mediated cellular adhesion and migration during wound repair Z Kopecki, R Arkell, BC Powell, AJ Cowin Journal of investigative dermatology 129 (8), 2031-2045, 2009 | 84 | 2009 |
