Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework D Cook, D Brown, R Alexander, R March, P Morgan, G Satterthwaite, ... Nature reviews Drug discovery 13 (6), 419-431, 2014 | 1342 | 2014 |
Diagnostic utility of exome sequencing for kidney disease EE Groopman, M Marasa, S Cameron-Christie, S Petrovski, VS Aggarwal, ... New England Journal of Medicine 380 (2), 142-151, 2019 | 599 | 2019 |
Rosuvastatin pharmacokinetics and pharmacogenetics in white and Asian subjects residing in the same environment E Lee, S Ryan, B Birmingham, J Zalikowski, R March, H Ambrose, ... Clinical Pharmacology & Therapeutics 78 (4), 330-341, 2005 | 550 | 2005 |
Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis A Kindmark, A Jawaid, CG Harbron, BJ Barratt, OF Bengtsson, ... The pharmacogenomics journal 8 (3), 186-195, 2008 | 403 | 2008 |
Impact of a five-dimensional framework on R&D productivity at AstraZeneca P Morgan, DG Brown, S Lennard, MJ Anderton, JC Barrett, U Eriksson, ... Nature reviews Drug discovery 17 (3), 167-181, 2018 | 376 | 2018 |
A genome‐wide screen for susceptibility loci in ankylosing spondylitis MA Brown, KD Pile, LG Kennedy, D Campbell, L Andrew, R March, ... Arthritis & Rheumatism: Official Journal of the American College of …, 1998 | 258 | 1998 |
Rare variant contribution to human disease in 281,104 UK Biobank exomes Q Wang, RS Dhindsa, K Carss, AR Harper, A Nag, I Tachmazidou, ... Nature 597 (7877), 527-532, 2021 | 249 | 2021 |
Susceptibility locus for IgA deficiency and common variable immunodeficiency in the HLA-DR3,-B8,-A1 haplotypes HW Schroeder, ZB Zhu, RE March, RD Campbell, SM Berney, ... Molecular medicine 4, 72-86, 1998 | 155 | 1998 |
Evaluation of fine mapping strategies for a multifactorial disease locus: systematic linkage and association analysis of IDDM1 in the HLA region on chromosome 6p21 M Herr, F Dudbridge, P Zavattari, F Cucca, C Guja, R March, ... Human molecular genetics 9 (9), 1291-1301, 2000 | 115 | 2000 |
Pharmacogenomics: the genomics of drug response R March Yeast 1 (1), 16-21, 2000 | 84 | 2000 |
Serious carbamazepine-induced hypersensitivity reactions associated with the HSP70 gene cluster A Alfirevic, T Mills, P Harrington, T Pinel, J Sherwood, A Jawaid, JC Smith, ... Pharmacogenetics and genomics 16 (4), 287-296, 2006 | 71 | 2006 |
Pharmacogenetics–legal, ethical and regulatory considerations R March, K Cheeseman, M Doherty Pharmacogenomics 2 (4), 317-327, 2001 | 54 | 2001 |
Exome-based rare-variant analyses in CKD S Cameron-Christie, CJ Wolock, E Groopman, S Petrovski, ... Journal of the American Society of Nephrology 30 (6), 1109-1122, 2019 | 49 | 2019 |
Gene mapping by linkage and association analysis RE March Molecular biotechnology 13, 113-122, 1999 | 48 | 1999 |
Genetic analysis of multicase families of visceral leishmaniasis in northeastern Brazil: no major role for class II or class III regions of HLA CS Peacock, CB Sanjeevi, MA Shaw, A Collins, RD Campbell, R March, ... Genes & Immunity 3 (6), 350-358, 2002 | 40 | 2002 |
A novel variant of the MHC‐linked hsp70, hsp70‐hom, is associated with rheumatoid arthritis SC Jenkins, RE March, RD Campbell, CM Milner Tissue antigens 56 (1), 38-44, 2000 | 39 | 2000 |
Structural Variants at the BRCA1/2 Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma A Ewing, A Meynert, M Churchman, GR Grimes, RL Hollis, CS Herrington, ... Clinical Cancer Research 27 (11), 3201-3214, 2021 | 33 | 2021 |
The classical human phosphoglucomutase (PGM1) isozyme polymorphism is generated by intragenic recombination. RE March, W Putt, M Hollyoake, JH Ives, JU Lovegrove, DA Hopkinson, ... Proceedings of the National Academy of Sciences 90 (22), 10730-10733, 1993 | 32 | 1993 |
Conditional ETDT analysis of the human leukocyte antigen region in type 1 diabetes BPC Koeleman, MH Herr, P Zavattari, F Dudbridge, R March, D Campbell, ... Annals of human genetics 64 (3), 215-221, 2000 | 27 | 2000 |
Automation and validation of DNA-banking systems M Thornton, A Gladwin, R Payne, R Moore, C Cresswell, D McKechnie, ... Drug discovery today 10 (20), 1369-1375, 2005 | 21 | 2005 |