| Mechanisms of copper ion mediated Huntington's disease progression JH Fox, JA Kama, G Lieberman, R Chopra, K Dorsey, V Chopra, ... PloS one 2 (3), e334, 2007 | 208 | 2007 |
| Iron accumulates in Huntington’s disease neurons: protection by deferoxamine J Chen, E Marks, B Lai, Z Zhang, JA Duce, LQ Lam, I Volitakis, AI Bush, ... PloS one 8 (10), e77023, 2013 | 162 | 2013 |
| Alterations in brain transition metals in Huntington disease: an evolving and intricate story HD Rosas, YI Chen, G Doros, DH Salat, N Chen, KK Kwong, A Bush, ... Archives of neurology 69 (7), 887-893, 2012 | 162 | 2012 |
| Cystamine increases l‐cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation JH Fox, DS Barber, B Singh, B Zucker, MK Swindell, F Norflus, R Buzescu, ... Journal of neurochemistry 91 (2), 413-422, 2004 | 138 | 2004 |
| Single-step detection of mutant huntingtin in animal and human tissues: a bioassay for Huntington’s disease A Weiss, D Abramowski, M Bibel, R Bodner, V Chopra, M DiFiglia, J Fox, ... Analytical biochemistry 395 (1), 8-15, 2009 | 136 | 2009 |
| A small-molecule therapeutic lead for Huntington's disease: preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse V Chopra, JH Fox, G Lieberman, K Dorsey, W Matson, P Waldmeier, ... Proceedings of the National Academy of Sciences 104 (42), 16685-16689, 2007 | 130 | 2007 |
| Transcriptional dysregulation in striatal projection-and interneurons in a mouse model of Huntington's disease: neuronal selectivity and potential neuroprotective role of HAP1 B Zucker, R Luthi-Carter, JA Kama, AW Dunah, EA Stern, JH Fox, ... Human molecular genetics 14 (2), 179-189, 2005 | 117 | 2005 |
| Brain mitochondrial iron accumulates in Huntington's disease, mediates mitochondrial dysfunction, and can be removed pharmacologically S Agrawal, J Fox, B Thyagarajan, JH Fox Free Radical Biology and Medicine 120, 317-329, 2018 | 114 | 2018 |
| GAMMA‐DIKETONE PERIPHERAL NEUROPATHY—I. QUANTITATIVE MORPHOMETRIC ANALYSES OF AXONAL ATROPHY AND SWELLING EJ Lehning, BS Jortner, JH Fox, JC Arezzo, T Kitano, RM LoPachin Journal of the Peripheral Nervous System 5 (4), 249-249, 2000 | 96 | 2000 |
| The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse … JH Fox, T Connor, V Chopra, K Dorsey, JA Kama, D Bleckmann, ... Molecular neurodegeneration 5, 1-12, 2010 | 95 | 2010 |
| Cysteine oxidation within N-terminal mutant huntingtin promotes oligomerization and delays clearance of soluble protein JH Fox, T Connor, M Stiles, J Kama, Z Lu, K Dorsey, G Liebermann, ... Journal of Biological Chemistry 286 (20), 18320-18330, 2011 | 63 | 2011 |
| Impact of high iron intake on cognition and neurodegeneration in humans and in animal models: a systematic review S Agrawal, KL Berggren, E Marks, JH Fox Nutrition reviews 75 (6), 456-470, 2017 | 61 | 2017 |
| Anti-inflammatory treatment with acetylsalicylate or rofecoxib is not neuroprotective in Huntington's disease transgenic mice F Norflus, A Nanje, CA Gutekunst, G Shi, J Cohen, M Bejarano, J Fox, ... Neurobiology of disease 17 (2), 319-325, 2004 | 50 | 2004 |
| Altered selenium status in Huntington's disease: neuroprotection by selenite in the N171-82Q mouse model Z Lu, E Marks, J Chen, J Moline, L Barrows, M Raisbeck, I Volitakis, ... Neurobiology of disease 71, 34-42, 2014 | 46 | 2014 |
| Neonatal iron supplementation potentiates oxidative stress, energetic dysfunction and neurodegeneration in the R6/2 mouse model of Huntington's disease KL Berggren, J Chen, J Fox, J Miller, L Dodds, B Dugas, L Vargas, ... Redox biology 4, 363-374, 2015 | 40 | 2015 |
| Huntingtons Disease Mice Infected with Toxoplasma gondii Demonstrate Early Kynurenine Pathway Activation, Altered CD8+ T-Cell Responses, and Premature … DW Donley, AR Olson, MF Raisbeck, JH Fox, JP Gigley PloS one 11 (9), e0162404, 2016 | 35 | 2016 |
| Neuronal ceroid-lipofuscinosis in a Labrador Retriever JH Rossmeisl Jr, R Duncan, J Fox, ES Herring, KD Inzana Journal of veterinary diagnostic investigation 15 (5), 457-460, 2003 | 34 | 2003 |
| Avian pox in eastern screech owls and barred owls from Florida SL Deem, DJ Heard, JH Fox Journal of Wildlife Diseases 33 (2), 323-327, 1997 | 32 | 1997 |
| Naturally occurring G M2 gangliosidosis in two Muntjak deer with pathological and biochemical features of human classical Tay-Sachs disease (type BG M2 gangliosidosis) J Fox, YT Li, G Dawson, A Alleman, J Johnsrude, J Schumacher, B Homer Acta neuropathologica 97, 57-62, 1999 | 31 | 1999 |
| Characterization of striatal neuronal loss and atrophy in the R6/2 mouse model of Huntington’s disease L Dodds, J Chen, K Berggren, J Fox PLoS currents 6, 2014 | 26 | 2014 |
