Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants DR Barnes, MA Rookus, L McGuffog, G Leslie, TM Mooij, J Dennis, ... Genetics in Medicine 22 (10), 1653-1666, 2020 | 101 | 2020 |
Characterization of the cancer spectrum in men with germline BRCA1 and BRCA2 pathogenic variants: results from the consortium of investigators of modifiers of BRCA1/2 (CIMBA) V Silvestri, G Leslie, DR Barnes, BA Agnarsson, K Aittomäki, E Alducci, ... JAMA oncology 6 (8), 1218-1230, 2020 | 55 | 2020 |
Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness VL Patel, EL Busch, TM Friebel, A Cronin, G Leslie, L McGuffog, J Adlard, ... Cancer research 80 (3), 624-638, 2020 | 54 | 2020 |
The zebrafish as an emerging model to study DNA damage in aging, cancer and other diseases ML Cayuela, KBM Claes, MG Ferreira, CM Henriques, F van Eeden, ... Frontiers in cell and developmental biology 6, 178, 2019 | 35 | 2019 |
Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers F Qian, MA Rookus, G Leslie, HA Risch, MH Greene, CM Aalfs, MA Adank, ... British journal of cancer 121 (2), 180-192, 2019 | 24 | 2019 |
Accurate quantification of homologous recombination in zebrafish: brca2 deficiency as a paradigm J Vierstraete, A Willaert, P Vermassen, PJ Coucke, A Vral, KBM Claes Scientific reports 7 (1), 16518, 2017 | 15 | 2017 |
Zebrafish as an in vivo screening tool to establish PARP inhibitor efficacy J Vierstraete, C Fieuws, A Willaert, A Vral, KBM Claes DNA repair 97, 103023, 2021 | 5 | 2021 |
Decreased DNA double‑strand break repair and enhanced chromosomal radiosensitivity in irradiated non‑tumorigenic human breast epithelial cells with a partial BRCA1 or BRCA2 … A Baert, MF Palermo, M Van Heetvelde, B Verstraete, J Depuydt, ... World Academy of Sciences Journal 2 (1), 19-27, 2020 | 3 | 2020 |
Atm deficient zebrafish model reveals conservation of the tumour suppressor function J Vierstraete, C Fieuws, D Creytens, J Van Dorpe, A Willaert, A Vral, ... 20th BeSHG meeting: Genome for all?, 2020 | 2 | 2020 |
In vivo PET/CT imaging in zebrafish using 18FF-FDG and 18FF-NaF L Nazario, J Vierstraete, J Bek 14th European Molecular Imaging Meeting (EMIM 2019), 2019 | 2 | 2019 |
Abstract B25: Isolation and engraftment of circulating tumor cells into zebrafish embryos to predict tumor response of ovarian cancer patients C Fieuws, J Vierstraete, K Van De Vijver, H Denys, KBM Claes Clinical Cancer Research 26 (11_Supplement), B25-B25, 2020 | 1 | 2020 |
Studying the functionality of the homologous repair pathway in zebrafish embryos: heading for an in vivo functional test to evaluate the pathogenicity of BRCA2 variants … J Vierstraete, A Willaert, P Vermassen, L Pieters, P Coucke, A Vral, ... 1st Joint meeting of the Belgian Society of Human Genetics (BeSHG) and the …, 2016 | 1 | 2016 |
Atm deficient zebrafish model reveals conservation of the tumour suppressor function and a role in fertility J Vierstraete, C Fieuws, D Creytens, J Van Dorpe, A Willaert, A Vral, ... Genes & Diseases 10 (2), 381, 2023 | | 2023 |
Re: Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness VL Patel, EL Busch, TM Friebel, A Cronin, G Leslie, L McGuffog, J Adlard, ... Journal of Urology 204 (3), 619-620, 2020 | | 2020 |
Zebrafish as a model to study DNA repair and developmental defects following loss of Brca2 or Atm J Vierstraete Ghent University, 2020 | | 2020 |
Faithfully recapitulating PARP inhibitor efficacy in zebrafish J Vierstraete, C Fieuws, A Willaert, A Vral, K Claes 12th Zebrafish Disease Models conference, 2019 | | 2019 |
Uncovering the role of atm in zebrafish J Vierstraete, A Vral, P Coucke, A Willaert, K Claes 11th Zebrafish Disease Models conference, 2018 | | 2018 |
Uncovering the role of zebrafish in atm J Vierstraete, A Willaert, P Coucke, A Vral, K Claes 6th OncoPoint research seminar, 2018 | | 2018 |
Accurate quantification of homologous recombination: a zebrafish brca2-/-model J Vierstraete, A Willaert, P Vermassen, L Pieters, P Coucke, A Vral, ... 5th OncoPoint research seminar, 2017 | | 2017 |
Study of homologous recombination repair in BRCA2 knockout zebrafish embryos J Vierstraete, A Willaert, P Coucke, A Vral, K Claes 17th Annual BeSHG meeting: Human genetics goes somatic, 2017 | | 2017 |