CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer E Sanij, KM Hannan, J Xuan, S Yan, JE Ahern, AS Trigos, N Brajanovski, ... Nature communications 11 (1), 2641, 2020 | 127 | 2020 |
Enhanced dependency of KRAS‐mutant colorectal cancer cells on RAD 51‐dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae M Kalimutho, AL Bain, B Mukherjee, P Nag, DM Nanayakkara, SK Harten, ... Molecular oncology 11 (5), 470-490, 2017 | 38 | 2017 |
Cep55 overexpression promotes genomic instability and tumorigenesis in mice D Sinha, P Nag, D Nanayakkara, PHG Duijf, A Burgess, P Raninga, ... Communications biology 3 (1), 593, 2020 | 30 | 2020 |
Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells KTK Giuliani, A Grivei, P Nag, X Wang, M Rist, K Kildey, B Law, MS Ng, ... Cell Death & Disease 13 (8), 739, 2022 | 26 | 2022 |
Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells MA Khan, P Nag, A Grivei, KTK Giuliani, X Wang, V Diwan, W Hoy, ... Cell Death & Disease 13 (2), 104, 2022 | 24 | 2022 |
Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress W Shi, T Vu, D Boucher, A Biernacka, J Nde, RK Pandita, J Straube, ... Blood, The Journal of the American Society of Hematology 129 (18), 2479-2492, 2017 | 23 | 2017 |
Blockade of PDGFRβ circumvents resistance to MEK-JAK inhibition via intratumoral CD8+ T-cells infiltration in triple-negative breast cancer M Kalimutho, D Sinha, D Mittal, S Srihari, D Nanayakkara, S Shafique, ... Journal of Experimental & Clinical Cancer Research 38, 1-18, 2019 | 19 | 2019 |
Underlying histopathology determines response to oxidative stress in cultured human primary proximal tubular epithelial cells MA Khan, X Wang, KTK Giuliani, P Nag, A Grivei, J Ungerer, W Hoy, ... International Journal of Molecular Sciences 21 (2), 560, 2020 | 17 | 2020 |
The 2-μm plasmid encoded protein Raf1 regulates both stability and copy number of the plasmid by blocking the formation of the Rep1–Rep2 repressor complex SM A. Rizvi, HK Prajapati, P Nag, SK Ghosh Nucleic acids research 45 (12), 7167-7179, 2017 | 12 | 2017 |
HYPOXIA AND INTERLEUKIN (IL)-1β SYNERGISTICALLY INDUCE CELLULAR SENESCENCE IN HUMAN PROXIMAL TUBULAR EPITHELIAL CELLS (PTEC) AJ Kassianos, K Giuliani, P Nag, S Hong, X Wang, RL Johnston, B Adams, ... Nephrology 28, 14-15, 2023 | | 2023 |
HYPOXIA AND INTERLEUKIN (IL)-1 beta SENSITIZE PROXIMAL TUBULE EPITHELIAL CELLS (PTEC) TO TRANSFORMING GROWTH FACTOR (TGF)-beta SIGNALLING KT Giuliani, RL Johnston, P Nag, A Grivei, MSY Ng, X Wang, J Ungerer, ... NEPHROLOGY 27, 27-28, 2022 | | 2022 |
BAICALEIN ATTENUATES ADENINE-INDUCED FERROPTOSIS IN HUMAN KIDNEY PRIMARY PROXIMAL TUBULAR EPITHELIAL CELLS (PTEC) VIA INDUCTION OF ANTIOXIDANT PATHWAYS MA Khan, P Nag, KTK Giuliani, X Wang, A Grivei, W Hoy, H Healy, ... NEPHROLOGY 26, 18-19, 2021 | | 2021 |
INFLAMMASOME SIGNALLING IN HUMAN HYPOXIC CHRONIC KIDNEY DISEASE (CKD) KTK Giuliani, A Grivei, P Nag, X Wang, J Ungerer, JM Forbes, H Healy, ... NEPHROLOGY 26, 18-18, 2021 | | 2021 |
POS-377 BAICALEIN ATTENUATES ADENINE-INDUCED FERROPTOSIS IN HUMAN KIDNEY PRIMARY PROXIMAL TUBULAR EPITHELIAL CELLS (PTEC) VIA MAINTENANCE OF HEME OXYGENASE-1 EXPRESSION MA KHAN, P Nag, K Giuliani, X Wang, A Grivei, W Hoy, HG Healy, ... Kidney International Reports 6 (4), S163, 2021 | | 2021 |
POS-438 KIDNEYS ON FIRE: DECIPHERING THE ROLE OF INFLAMMASOME ACTIVATION IN HUMAN CHRONIC KIDNEY DISEASE (CKD) K GIULIANI, A Grivei, P Nag, X Wang, AJ Kassianos, H Healy Kidney International Reports 6 (4), S190-S191, 2021 | | 2021 |
INDUCTION OF FERROPTOTIC DEATH IN HUMAN PRIMARY PROXIMAL TUBULAR EPITHELIAL CELLS (PTEC) DURING ADENINE-INDUCED CHRONIC KIDNEY DISEASE MA Khan, P Nag, K Giuliani, XA Wang, A Grivei, W Hoy, H Healy, V Diwan, ... NEPHROLOGY 25, 40-40, 2020 | | 2020 |