Cardioprotection and lifespan extension by the natural polyamine spermidine T Eisenberg, M Abdellatif, S Schroeder, U Primessnig, S Stekovic, T Pendl, ... Nature medicine 22 (12), 1428-1438, 2016 | 945 | 2016 |
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells NR Mathew, F Baumgartner, L Braun, D O'Sullivan, S Thomas, ... Nature medicine 24 (3), 282-291, 2018 | 259 | 2018 |
HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα A Di Rita, A Peschiaroli, P D′ Acunzo, D Strobbe, Z Hu, J Gruber, ... Nature communications 9 (1), 3755, 2018 | 191 | 2018 |
Cargo-selective SNX-BAR proteins mediate retromer trimer independent retrograde transport A Kvainickas, A Jimenez-Orgaz, H Nägele, Z Hu, J Dengjel, F Steinberg Journal of Cell Biology 216 (11), 3677-3693, 2017 | 166 | 2017 |
The flavonoid 4, 4′-dimethoxychalcone promotes autophagy-dependent longevity across species D Carmona-Gutierrez, A Zimmermann, K Kainz, F Pietrocola, G Chen, ... Nature communications 10 (1), 651, 2019 | 120 | 2019 |
Spatially distinct pools of TORC1 balance protein homeostasis R Hatakeyama, MP Péli-Gulli, Z Hu, M Jaquenoud, GMG Osuna, A Sardu, ... Molecular Cell 73 (2), 325-338. e8, 2019 | 105 | 2019 |
Multilayered control of protein turnover by TORC1 and Atg1 Z Hu, S Raucci, M Jaquenoud, R Hatakeyama, M Stumpe, R Rohr, ... Cell reports 28 (13), 3486-3496. e6, 2019 | 75 | 2019 |
Role of influenza A virus NP acetylation on viral growth and replication S Giese, K Ciminski, H Bolte, ÉA Moreira, S Lakdawala, Z Hu, Q David, ... Nature communications 8 (1), 1259, 2017 | 53 | 2017 |
Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid–induced mTORC1 signaling A Kvainickas, H Nägele, W Qi, L Dokládal, A Jimenez-Orgaz, L Stehl, ... Journal of Cell Biology 218 (9), 3019-3038, 2019 | 49 | 2019 |
Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock A Brenna, I Olejniczak, R Chavan, JA Ripperger, S Langmesser, ... Elife 8, e50925, 2019 | 34 | 2019 |
TORC1 determines Fab1 lipid kinase function at signaling endosomes and vacuoles Z Chen, PC Malia, R Hatakeyama, R Nicastro, Z Hu, MP Péli-Gulli, J Gao, ... Current Biology 31 (2), 297-309. e8, 2021 | 32 | 2021 |
Phosphoproteomic responses of TORC1 target kinases reveal discrete and convergent mechanisms that orchestrate the quiescence program in yeast L Dokladal, M Stumpe, Z Hu, M Jaquenoud, J Dengjel, C De Virgilio Cell Reports 37 (13), 2021 | 27 | 2021 |
ULK1 phosphorylation of striatin activates protein phosphatase 2A and autophagy Z Hu, DS Sankar, B Vu, A Leytens, C Vionnet, W Wu, M Stumpe, ... Cell Reports 36 (13), 2021 | 23 | 2021 |
Influenza A virus induces autophagosomal targeting of ribosomal proteins AC Becker, M Gannage, S Giese, Z Hu, S Abou-Eid, C Roubaty, P Paul, ... Molecular & Cellular Proteomics 17 (10), 1909-1921, 2018 | 23 | 2018 |
Feedback inhibition of the Rag GTPase GAP complex Lst4-Lst7 safeguards TORC1 from hyperactivation by amino acid signals MP Péli-Gulli, S Raucci, Z Hu, J Dengjel, C De Virgilio Cell reports 20 (2), 281-288, 2017 | 22 | 2017 |
Snf1/AMPK fine-tunes TORC1 signaling in response to glucose starvation M Caligaris, R Nicastro, Z Hu, F Tripodi, JE Hummel, B Pillet, MA Deprez, ... Elife 12, e84319, 2023 | 20 | 2023 |
Axitinib and sorafenib are potent in tyrosine kinase inhibitor resistant chronic myeloid leukemia cells S Halbach, Z Hu, C Gretzmeier, J Ellermann, FU Wöhrle, J Dengjel, ... Cell Communication and Signaling 14, 1-7, 2016 | 20 | 2016 |
Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery C Walter, A Marada, T Suhm, R Ernsberger, V Muders, C Kücükköse, ... Nature communications 12 (1), 1-12, 2021 | 19 | 2021 |
Global phosphoproteomics pinpoints uncharted Gcn2-mediated mechanisms of translational control L Dokládal, M Stumpe, B Pillet, Z Hu, GMG Osuna, D Kressler, J Dengjel, ... Molecular cell 81 (9), 1879-1889. e6, 2021 | 19 | 2021 |
Downregulation of autophagy by Met30-mediated Atg9 ubiquitination Y Feng, AR Ariosa, Y Yang, Z Hu, J Dengjel, DJ Klionsky Proceedings of the National Academy of Sciences 118 (1), e2005539118, 2021 | 15 | 2021 |